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Accurate segmentation of brain tissue in magnetic resonance images (MRI) is a diffcult task due to different types of brain abnormalities. Using information and features from multimodal MRI including T1, T1-weighted inversion recovery…

Computer Vision and Pattern Recognition · Computer Science 2019-03-07 Yongpei Zhu , Zicong Zhou , Guojun Liao , Qianxi Yang , Kehong Yuan

Enlarged perivascular spaces (PVS) are increasingly recognized as biomarkers of cerebral small vessel disease, Alzheimer's disease, stroke, and aging-related neurodegeneration. However, manual segmentation of PVS is time-consuming and…

Skull stripping magnetic resonance images (MRI) of the human brain is an important process in many image processing techniques, such as automatic segmentation of brain structures. Numerous methods have been developed to perform this task,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-16 Hjalti Thrastarson , Lotta M. Ellingsen

The incomplete hippocampal inversion (IHI) is an atypical anatomical pattern of the hippocampus. However, the hippocampus is not a homogeneous structure, as it consists of segregated subfields with specific characteristics. While IHI is not…

Neurons and Cognition · Quantitative Biology 2023-05-01 Agustina Fragueiro , Giorgia Committeri , Claire Cury

Medical image segmentation, which aims to automatically extract anatomical or pathological structures, plays a key role in computer-aided diagnosis and disease analysis. Despite the problem has been widely studied, existing methods are…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Han Zhang , Lok Ming Lui

Automated volumetric segmentation of the pancreas on cross-sectional imaging is needed for diagnosis and follow-up of pancreatic diseases. While CT-based pancreatic segmentation is more established, MRI-based segmentation methods are…

Subcortical segmentation remains challenging despite its important applications in quantitative structural analysis of brain MRI scans. The most accurate method, manual segmentation, is highly labor intensive, so automated tools like…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Aaron Cao , Vishwanatha M. Rao , Kejia Liu , Xinrui Liu , Andrew F. Laine , Jia Guo

Our understanding of organs at risk is progressing to include physical small tissues such as coronary arteries and the radiosensitivities of many small organs and tissues are high. Therefore, the accurate segmentation of small volumes in…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Jianxin Zhou , Kadishe Fejza , Massimiliano Salvatori , Daniele Della Latta , Gregory M. Hermann , Angela Di Fulvio

Objective: Hydrocephalus is a medical condition in which there is an abnormal accumulation of cerebrospinal fluid (CSF) in the brain. Segmentation of brain imagery into brain tissue and CSF (before and after surgery, i.e. pre-op vs. postop)…

Image and Video Processing · Electrical Eng. & Systems 2018-09-11 Venkateswararao Cherukuri , Peter Ssenyonga , Benjamin C. Warf , Abhaya V. Kulkarni , Vishal Monga , Steven J. Schiff

Segmentation is one of the most important tasks in MRI medical image analysis and is often the first and the most critical step in many clinical applications. In brain MRI analysis, head segmentation is commonly used for measuring and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Haleh Akrami , Wenhui Cui , Anand A Joshi , Richard M. Leahy

Planning of radiotherapy involves accurate segmentation of a large number of organs at risk, i.e. organs for which irradiation doses should be minimized to avoid important side effects of the therapy. We propose a deep learning method for…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Pawel Mlynarski , Hervé Delingette , Hamza Alghamdi , Pierre-Yves Bondiau , Nicholas Ayache

Automated segmentation of anatomical sub-regions with high precision has become a necessity to enable the quantification and characterization of cells/ tissues in histology images. Currently, a machine learning model to analyze…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Hosein Barzekar , Hai Ngu , Han Hui Lin , Mohsen Hejrati , Steven Ray Valdespino , Sarah Chu , Baris Bingol , Somaye Hashemifar , Soumitra Ghosh

Deep learning models for medical image segmentation often struggle when deployed across different datasets due to domain shifts - variations in both image appearance, known as style, and population-dependent anatomical characteristics,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Hoda Kalabizadeh , Ludovica Griffanti , Pak-Hei Yeung , Ana I. L. Namburete , Nicola K. Dinsdale , Konstantinos Kamnitsas

The hippocampus is a seminal structure in the most common surgically-treated form of epilepsy. Accurate segmentation of the hippocampus aids in establishing asymmetry regarding size and signal characteristics in order to disclose the likely…

Computer Vision and Pattern Recognition · Computer Science 2016-10-27 Mohammad-Parsa Hosseini , Mohammad-Reza Nazem-Zadeh , Dario Pompili , Kourosh Jafari-Khouzani , Kost Elisevich , Hamid Soltanian-Zadeh

Deep learning has shown great potential for automated medical image segmentation to improve the precision and speed of disease diagnostics. However, the task presents significant difficulties due to variations in the scale, shape, texture,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-06 Shahzaib Iqbal , Tariq M. Khan , Syed S. Naqvi , Asim Naveed , Erik Meijering

This report provides an overview of the current state of the art deep learning architectures and optimisation techniques, and uses the ADNI hippocampus MRI dataset as an example to compare the effectiveness and efficiency of different…

Machine Learning · Computer Science 2015-05-11 Matthew Lai

Precise 3D segmentation of cerebral vasculature from T1-weighted contrast-enhanced (T1CE) MRI is crucial for safe neurosurgical planning. Manual delineation is time-consuming and prone to inter-observer variability, while current automated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Mohammad Jafari Vayeghan , Niloufar Delfan , Mehdi Tale Masouleh , Mansour Parvaresh Rizi , Behzad Moshiri

Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…

Computer Vision and Pattern Recognition · Computer Science 2018-11-15 Kaisar Kushibar , Sergi Valverde , Sandra Gonzalez-Villa , Jose Bernal , Mariano Cabezas , Arnau Oliver , Xavier Llado

Medical image segmentation is a cornerstone of modern clinical diagnostics. While Vision Transformers that leverage shifted window-based self-attention have established new benchmarks in this field, they are often hampered by a critical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Fuchen Zheng , Xinyi Chen , Weixuan Li , Quanjun Li , Junhua Zhou , Xiaojiao Guo , Xuhang Chen , Chi-Man Pun , Shoujun Zhou