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We demonstrate instrumentation and methods to enable fluorescence-detected photothermal infrared (F-PTIR) microscopy, then demonstrate the utility of F-PTIR to characterize the composition within phase-separated domains of model amorphous…

Temporal ghost imaging (TGI) enables ultrafast temporal signal recovery using slow detectors, offering a promising route for high-speed mid-infrared (MIR) detection. However, conventional schemes remain limited in temporal resolution by the…

Optics · Physics 2026-05-22 Wen Zhang , Kun Huang , Zhibin Zhao , Huijie Ma , Ziyu He , Jianan Fang , Heping Zeng

Fourier ptychography (FP) is a promising computational imaging technique that overcomes the physical space-bandwidth product (SBP) limit of a conventional microscope by applying angular diversity illuminations. However, to date, the…

Optics · Physics 2018-10-17 An Pan , Yan Zhang , Kai Wen , Maosen Li , Meiling Zhou , Junwei Min , Ming Lei , Baoli Yao

Nonlinear interferometry has widespread applications in sensing, spectroscopy, and imaging. However, most implementations require highly reflective mirrors and precise optical alignment, drastically reducing their versatility and usability…

Understanding the biophysical and biochemical properties of molecular nanocarriers under physiological conditions and with minimal interference is crucial for advancing nanomedicine, photopharmacology, drug delivery, nanotheranostics and…

Digital holographic microscopy (DHM) applied to quantitative phase imaging (QPI) has been successfully demonstrated as a powerful label-free method to analyse the optical properties of cells. Spatially multiplexed interferometric microscopy…

Spectral imaging is a fundamental diagnostic technique with widespread application. Conventional spectral imaging approaches have intrinsic limitations on spatial and spectral resolutions due to the physical components they rely on. To…

Image and Video Processing · Electrical Eng. & Systems 2021-06-07 Figen S. Oktem , Oğuzhan Fatih Kar , Can Deniz Bezek , Farzad Kamalabadi

Photothermal-Induced Resonance (PTIR) is increasingly used in the measurement of infrared absorption spectra of sub-micrometer objects. The technique measures IR absorption spectra by relying on the photothermal effect induced by a rapid…

Chemical Physics · Physics 2019-11-28 Luca Quaroni

Detecting mid-infrared (MIR) radiation has significant astronomical applications, although limited by unsatisfactory MIR detectors. Here we reported on the realization of a MIR up-conversion interferometer based on synthetic long base-line…

Instrumentation and Methods for Astrophysics · Physics 2024-09-16 Zhao-Qi-Zhi Han , Zheng Ge , Wen-Tao Luo , Yi-Fu Cai , Xiao-Hua Wang , Li Chen , Wu-Zhen Li , Zhi-Yuan Zhou , Bao-Sen Shi

Artificial nanostructures with ultrafine and deep-subwavelength feature sizes have emerged as a paradigm-shifting platform to advanced light field management, becoming a key building block for high-performance integrated optoelectronics and…

We report on the design of an all-mirror wavefront-division interferometer capable of spectroscopic studies across multiple spectral ranges$\unicode{x2013}$from the plasma frequencies of metals to terahertz wavelengths and beyond. The…

Recently, it was discovered that microsphere can generate super-resolution focusing beyond diffraction limit. This has led to the development of an exciting super-resolution imaging technique -microsphere nanoscopy- that features a record…

Optics · Physics 2021-08-26 Zengbo Wang

Molecular and atomic imaging required the development of electron and scanning probe microscopies to surpass the physical limits dictated by diffraction. Nano-infrared experiments and pico-cavity tip-enhanced Raman spectroscopy imaging…

Non-destructive testing (NDT) is crucial for ensuring product quality and safety across various industries. Conventional methods such as ultrasonic, terahertz, and X-ray imaging have limitations in terms of probe-contact requirement, depth…

Imaging below the diffraction limit is always a public interest because of the restricted resolution of conventional imaging systems. To beat the limit, evanescent harmonics decaying in space must participate in the imaging process. Here,…

Optics · Physics 2019-10-02 Tie-Jun Huang , Li-Zheng Yin , Ya Shuang , Jiang-Yu Liu , Yunhua Tan , Pu-Kun Liu

Diffraction limit is manifested in the loss of high spatial frequency information that results from decay of evanescent waves. As a result, conventional far-field optics yields no information about an object's subwavelength features. Here…

Optics · Physics 2012-01-24 Leonid Alekseyev , Evgenii Narimanov , Jacob Khurgin

In recent years several methods to overcome diffraction limit in the far field microscopy have been demonstrated. Still the problem of superresolution is reliably solved only for fluorescent microscopy, giving a resolution of up to 20-30nm.…

Optics · Physics 2013-09-03 Yu. V. Miklyaev , S. A. Asselborn , K. A. Zaytsev , M. Ya. Darscht

Photothermal-Induced Resonance (PTIR) spectroscopy and imaging with infrared light has seen increasing application in molecular spectroscopy of biological samples. The appeal of the technique lies in its capability to provide information…

Quantitative Methods · Quantitative Biology 2019-11-19 Luca Quaroni

Coherent diffractive imaging is unique as the only route for achieving diffraction-limited spatial resolution in the extreme ultraviolet and X-ray regions, limited only by the wavelength of the light. Recently, advances in coherent short…

Near-infrared (NIR) hyperspectral imaging has become a critical tool in modern analytical science. However, conventional NIR hyperspectral imaging systems face challenges including high cost, bulky instrumentation, and inefficient data…

Image and Video Processing · Electrical Eng. & Systems 2025-08-21 Yutong Li , Zhenming Yu , Liming Cheng , Jiayu Di , Liang Lin , Jingyue Ma , Tongshuo Zhang , Yue Zhou , Haiying Zhao , Kun Xu
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