Related papers: Neural Mixed Effects for Nonlinear Personalized Pr…
Large language model (LLM)-powered assistants have recently integrated memory mechanisms that record user preferences, leading to more personalized and user-aligned responses. However, irrelevant personalized memories are often introduced…
Understanding interaction effects among variables is important for regression modeling in various applications. The conventional approach of quantifying interactions as the product of variables often lacks clear interpretability, especially…
Simulations of complex physical systems are typically realized by discretizing partial differential equations (PDEs) on unstructured meshes. While neural networks have recently been explored for surrogate and reduced order modeling of PDE…
Nonlinear Mixed effects models are hidden variables models that are widely used in many fields such as pharmacometrics. In such models, the distribution characteristics of hidden variables can be specified by including several parameters…
Mood disorders are common and associated with significant morbidity and mortality. Early diagnosis has the potential to greatly alleviate the burden of mental illness and the ever increasing costs to families and society. Mobile devices…
The field of neuroimaging has truly become data rich, and novel analytical methods capable of gleaning meaningful information from large stores of imaging data are in high demand. Those methods that might also be applicable on the level of…
Nonlinear mixed effects models represent a powerful tool to simultaneously analyze data from several individuals. In this study a compartmental model of leucine kinetics is examined and extended with a stochastic differential equation to…
Modern neural networks (NNs) often achieve high predictive accuracy but are poorly calibrated, producing overconfident predictions even when wrong. This miscalibration poses serious challenges in applications where reliable uncertainty…
We propose the Intuitive Reasoning Network (IRENE) - a novel neural model for intuitive psychological reasoning about agents' goals, preferences, and actions that can generalise previous experiences to new situations. IRENE combines a graph…
The predictive advantage of combining several different predictive models is widely accepted. Particularly in time series forecasting problems, this combination is often dynamic to cope with potential non-stationary sources of variation…
Network meta-analysis (NMA) allows the combination of direct and indirect evidence from a set of randomized clinical trials. Performing NMA using individual patient data (IPD) is considered as a "gold standard" approach as it provides…
Objective: In randomized clinical trials, prediction models can be used to explore the relationships between patients' variables (e.g., clinical, pathological, or lifestyle variables, and also biomarker or genomic data) and treatment effect…
This paper considers nonparametric regression from strongly mixing observations. The proposed approach is based on deep neural networks with minimum error entropy (MEE) principle. We study two estimators: the non-penalized deep neural…
We present a computational motivation for restricted maximum likelihood (REML) estimation in linear mixed models using an expectation--maximization (EM) algorithm. At each iteration, maximum likelihood (ML) and REML solve the same…
Depression is ranked as the largest contributor to global disability and is also a major reason for suicide. Still, many individuals suffering from forms of depression are not treated for various reasons. Previous studies have shown that…
Maximum likelihood or restricted maximum likelihood (REML) estimates of the parameters in linear mixed-effects models can be determined using the lmer function in the lme4 package for R. As for most model-fitting functions in R, the model…
With the widespread adoption of large language models (LLMs), understanding their personality representation mechanisms has become critical. As a novel paradigm in Personality Editing, most existing methods employ neuron-editing to locate…
Conventional federated learning (FL) frameworks often suffer from training degradation due to data uncertainty and heterogeneity across local clients. Probabilistic approaches such as Bayesian neural networks (BNNs) can mitigate this issue…
Understanding and interpreting how machine learning (ML) models make decisions have been a big challenge. While recent research has proposed various technical approaches to provide some clues as to how an ML model makes individual…
In this paper the application of uncertainty modeling to convolutional neural networks is evaluated. A novel method for adjusting the network's predictions based on uncertainty information is introduced. This allows the network to be either…