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We present a deep learning framework for volumetric speckle reduction in optical coherence tomography (OCT) based on a conditional generative adversarial network (cGAN) that leverages the volumetric nature of OCT data. In order to utilize…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Bhaskara Rao Chintada , Sebastián Ruiz-Lopera , René Restrepo , Brett E. Bouma , Martin Villiger , Néstor Uribe-Patarroyo

We cast the problem of image denoising as a domain translation problem between high and low noise domains. By modifying the cycleGAN model, we are able to learn a mapping between these domains on unpaired retinal optical coherence…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Ilja Manakov , Markus Rohm , Christoph Kern , Benedikt Schworm , Karsten Kortuem , Volker Tresp

Retinal optical coherence tomography (OCT) images provide crucial insights into the health of the posterior ocular segment. Therefore, the advancement of automated image analysis methods is imperative to equip clinicians and researchers…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Jiahao Wang , Hong Peng , Shengchao Chen , Sufen Ren

Purpose: To develop a deep learning approach to de-noise optical coherence tomography (OCT) B-scans of the optic nerve head (ONH). Methods: Volume scans consisting of 97 horizontal B-scans were acquired through the center of the ONH using a…

Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…

Optical coherence tomography (OCT) is a prevalent, interferometric, high-resolution imaging method with broad biomedical applications. Nonetheless, OCT images suffer from an artifact, called speckle which degrades the image quality. Digital…

Few-shot learning aims to generalize to novel classes with only a few samples with class labels. Research in few-shot learning has borrowed techniques from transfer learning, metric learning, meta-learning, and Bayesian methods. These…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Jaya Krishna Mandivarapu , Eric bunch , Glenn fung

Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-30 Yijie Zhang , Tairan Liu , Manmohan Singh , Yilin Luo , Yair Rivenson , Kirill V. Larin , Aydogan Ozcan

Accurate segmentation of retinal fluids in 3D Optical Coherence Tomography images is key for diagnosis and personalized treatment of eye diseases. While deep learning has been successful at this task, trained supervised models often fail…

Computer Vision and Pattern Recognition · Computer Science 2022-08-05 Alvaro Gomariz , Huanxiang Lu , Yun Yvonna Li , Thomas Albrecht , Andreas Maunz , Fethallah Benmansour , Alessandra M. Valcarcel , Jennifer Luu , Daniela Ferrara , Orcun Goksel

Deep neural networks (DNNs) have been widely used for medical image analysis. However, the lack of access a to large-scale annotated dataset poses a great challenge, especially in the case of rare diseases, or new domains for the research…

Image and Video Processing · Electrical Eng. & Systems 2021-07-02 Sungho Suh , Sojeong Cheon , Wonseo Choi , Yeon Woong Chung , Won-Kyung Cho , Ji-Sun Paik , Sung Eun Kim , Dong-Jin Chang , Yong Oh Lee

Medical imaging systems are commonly assessed by use of objective image quality measures. Supervised deep learning methods have been investigated to implement numerical observers for task-based image quality assessment. However, labeling…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Shenghua He , Weimin Zhou , Hua Li , Mark A. Anastasio

Reducing the bit-depth is an effective approach to lower the cost of optical coherence tomography (OCT) systems and increase the transmission efficiency in data acquisition and telemedicine. However, a low bit-depth will lead to the…

Image and Video Processing · Electrical Eng. & Systems 2021-02-03 Qiangjiang Hao , Kang Zhou , Jianlong Yang , Liyang Fang , Zhengjie Chai , Yuhui Ma , Yan Hu , Shenghua Gao , Jiang Liu

Single-shot imaging with femtosecond X-ray lasers is a powerful measurement technique that can achieve both high spatial and temporal resolution. However, its accuracy has been severely limited by the difficulty of applying conventional…

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Optical coherence tomography (OCT) is an important interferometric diagnostic technique which provides cross-sectional views of the subsurface microstructure of biological tissues. However, the imaging quality of high-speed OCT is limited…

Computer Vision and Pattern Recognition · Computer Science 2015-03-13 Liheng Bian , Jinli Suo , Feng Chen , Qionghai Dai

Convolutional neural networks (CNNs) have achieved exciting performance in joint segmentation of optic disc and optic cup on single-institution datasets. However, their clinical translation is hindered by two major challenges: limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yusong Xiao , Yuxuan Wu , Li Xiao , Gang Qu , Haiye Huo , Yu-Ping Wang

Speckle is an intrinsic pattern in optical coherence tomography (OCT) that obscures fine image features and degrades effective resolution. In this study, we propose a numerical speckle reduction method based on the dispersed scatterer model…

Both few-shot learning and domain adaptation sub-fields in Computer Vision have seen significant recent progress in terms of the availability of state-of-the-art algorithms and datasets. Frameworks have been developed for each sub-field;…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Bharadwaj Ravichandran , Alexander Lynch , Sarah Brockman , Brandon RichardWebster , Dawei Du , Anthony Hoogs , Christopher Funk

Optical Coherence Tomography (OCT) is one of the most emerging imaging modalities that has been used widely in the field of biomedical imaging. From its emergence in 1990's, plenty of hardware and software improvements have been made. Its…

Computer Vision and Pattern Recognition · Computer Science 2014-11-18 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Despite the indispensable role of X-ray computed tomography (CT) in diagnostic medicine field, the associated ionizing radiation is still a major concern considering that it may cause genetic and cancerous diseases. Decreasing the exposure…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang