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We present a novel dual-head deep learning architecture for protein-protein interaction modeling that enables simultaneous prediction of binding affinity ($\Delta G$) and mutation-induced affinity changes ($\Delta\Delta G$) using only…

Quantitative Methods · Quantitative Biology 2025-09-30 Supantha Dey , Ratul Chowdhury

In this paper, we propose a binarized neural network learning method called BiDet for efficient object detection. Conventional network binarization methods directly quantize the weights and activations in one-stage or two-stage detectors…

Computer Vision and Pattern Recognition · Computer Science 2020-03-10 Ziwei Wang , Ziyi Wu , Jiwen Lu , Jie Zhou

Computational saliency models for still images have gained significant popularity in recent years. Saliency prediction from videos, on the other hand, has received relatively little interest from the community. Motivated by this, in this…

Computer Vision and Pattern Recognition · Computer Science 2017-11-16 Cagdas Bak , Aysun Kocak , Erkut Erdem , Aykut Erdem

Various networks such as cloud computing, water/gas/electricity networks, wireless sensor networks, transportation networks, and 4G/5G networks, have become an integral part of our daily lives. A binary-state network (BN) is often used to…

Discrete Mathematics · Computer Science 2021-08-03 Wei-Chang Yeh

Power flow analysis plays a critical role in the control and operation of power systems. The high computational burden of traditional solution methods led to a shift towards data-driven approaches, exploiting the availability of digital…

Systems and Control · Electrical Eng. & Systems 2024-09-17 Victor Eeckhout , Hossein Fani , Md Umar Hashmi , Geert Deconinck

Although physics-informed neural networks (PINNs) have shown great potential in dealing with nonlinear partial differential equations (PDEs), it is common that PINNs will suffer from the problem of insufficient precision or obtaining…

Machine Learning · Computer Science 2024-10-07 Feilong Jiang , Xiaonan Hou , Min Xia

Multi-behavior recommendation (MBR) aims to improve the performance w.r.t. the target behavior (i.e., purchase) by leveraging auxiliary behaviors (e.g., click, favourite). However, in real-world scenarios, a recommendation method often…

Information Retrieval · Computer Science 2026-01-13 Wenhao Lai , Weike Pan , Zhong Ming

Equilibrium Propagation (EP) is an algorithm intrinsically adapted to the training of physical networks, thanks to the local updates of weights given by the internal dynamics of the system. However, the construction of such a hardware…

Neural and Evolutionary Computing · Computer Science 2021-04-20 Jérémie Laydevant , Maxence Ernoult , Damien Querlioz , Julie Grollier

There is a perceived dichotomy between structure-based and descriptor-based molecular representations used for predictive chemistry tasks. Here, we study the performance, generalizability, and interpretability of the recently proposed…

Chemical Physics · Physics 2022-03-14 Thijs Stuyver , Connor W. Coley

We consider the estimation of treatment effects in settings when multiple treatments are assigned over time and treatments can have a causal effect on future outcomes or the state of the treated unit. We propose an extension of the…

Econometrics · Economics 2021-06-18 Greg Lewis , Vasilis Syrgkanis

Accurate understanding of muscle activation and muscle forces plays an essential role in neuro-rehabilitation and musculoskeletal disorder treatments. Computational musculoskeletal modeling has been widely used as a powerful non-invasive…

Signal Processing · Electrical Eng. & Systems 2024-12-10 Shuhao Ma , Yu Cao , Ian D. Robertson , Chaoyang Shi , Jindong Liu , Zhi-Qiang Zhang

We introduce a machine-learning approach to predict the complex non-Markovian dynamics of supercooled liquids from static averaged quantities. Compared to techniques based on particle propensity, our method is built upon a theoretical…

Disordered Systems and Neural Networks · Physics 2023-03-17 Simone Ciarella , Massimiliano Chiappini , Emanuele Boattini , Marjolein Dijkstra , Liesbeth M. C. Janssen

To investigate the structure of individual differences in performance on behavioral tasks, Haaf and Rouder (2017) developed a class of hierarchical Bayesian mixed models with varying levels of constraint on the individual effects. The…

Applications · Statistics 2022-10-24 Thomas J. Faulkenberry

We propose a novel regularization algorithm to train deep neural networks, in which data at training time is severely biased. Since a neural network efficiently learns data distribution, a network is likely to learn the bias information to…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Byungju Kim , Hyunwoo Kim , Kyungsu Kim , Sungjin Kim , Junmo Kim

Energy-based models (EBMs) have experienced a resurgence within machine learning in recent years, including as a promising alternative for probabilistic regression. However, energy-based regression requires a proposal distribution to be…

Machine Learning · Computer Science 2023-11-08 Fredrik K. Gustafsson , Martin Danelljan , Thomas B. Schön

Human activity recognition using deep learning techniques has become increasing popular because of its high effectivity with recognizing complex tasks, as well as being relatively low in costs compared to more traditional machine learning…

Computer Vision and Pattern Recognition · Computer Science 2022-04-29 Wei Zhong Tee , Rushit Dave , Naeem Seliya , Mounika Vanamala

Animals learn to predict external contingencies from experience through a process of conditioning. A natural mechanism for conditioning is stimulus substitution, whereby the neuronal response to a stimulus with no prior behavioral…

Neurons and Cognition · Quantitative Biology 2024-09-23 Pantelis Vafidis , Antonio Rangel

This paper introduces a physics-informed machine learning approach for pathloss prediction. This is achieved by including in the training phase simultaneously (i) physical dependencies between spatial loss field and (ii) measured pathloss…

Machine Learning · Statistics 2023-12-15 Steffen Limmer , Alberto Martinez Alba , Nicola Michailow

This paper addresses the challenge of jointly modeling user intent diversity and behavioral uncertainty in recommender systems. A unified representation learning framework is proposed. The framework builds a multi-intent representation…

Information Retrieval · Computer Science 2025-09-08 Wei Xu , Jiasen Zheng , Junjiang Lin , Mingxuan Han , Junliang Du

Motivated by the problem of predicting sleep states, we develop a mixed effects model for binary time series with a stochastic component represented by a Gaussian process. The fixed component captures the effects of covariates on the…

Methodology · Statistics 2018-10-23 Xu Gao , Babak Shahbaba , Hernando Ombao