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The knockoff filter is a recent false discovery rate (FDR) control method for high-dimensional linear models. We point out that knockoff has three key components: ranking algorithm, augmented design, and symmetric statistic, and each…

Statistics Theory · Mathematics 2024-02-14 Zheng Tracy Ke , Jun S. Liu , Yucong Ma

In this work we study an adaptive step-down procedure for testing $m$ hypotheses. It stems from the repeated use of the false discovery rate controlling the linear step-up procedure (sometimes called BH), and makes use of the critical…

Statistics Theory · Mathematics 2009-04-01 Yulia Gavrilov , Yoav Benjamini , Sanat K. Sarkar

Identifying signals that replicate across multiple studies is essential for establishing robust scientific evidence, yet existing methods for high-dimensional replicability analysis either rely on restrictive modeling assumptions, are…

Methodology · Statistics 2026-03-05 Haochen Lei , Yan Li , Hongyuan Cao

A new online multiple testing procedure is described in the context of anomaly detection, which controls the False Discovery Rate (FDR). An accurate anomaly detector must control the false positive rate at a prescribed level while keeping…

Methodology · Statistics 2024-12-17 Etienne Krönert , Alain Célisse , Dalila Hattab

We address challenges in variable selection with highly correlated data that are frequently present in finance, economics, but also in complex natural systems as e.g. weather. We develop a robustified version of the knockoff framework,…

Econometrics · Economics 2022-06-14 Konstantin Görgen , Abdolreza Nazemi , Melanie Schienle

Consider the problem of simultaneously testing null hypotheses H_1,...,H_s. The usual approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate (FWER), the probability of…

Statistics Theory · Mathematics 2007-06-13 E. L. Lehmann , Joseph P. Romano

We propose the group knockoff filter, a method for false discovery rate control in a linear regression setting where the features are grouped, and we would like to select a set of relevant groups which have a nonzero effect on the response.…

Methodology · Statistics 2016-02-12 Ran Dai , Rina Foygel Barber

Sum-based global tests are highly popular in multiple hypothesis testing. In this paper we propose a general closed testing procedure for sum tests, which provides lower confidence bounds for the proportion of true discoveries (TDP),…

Methodology · Statistics 2023-04-21 Anna Vesely , Livio Finos , Jelle J. Goeman

We consider the problem of variable selection in high-dimensional statistical models where the goal is to report a set of variables, out of many predictors $X_1, \dotsc, X_p$, that are relevant to a response of interest. For linear…

Methodology · Statistics 2019-03-20 Adel Javanmard , Hamid Javadi

The local false discovery rate (lfdr) of Efron et al. (2001) enjoys major conceptual and decision-theoretic advantages over the false discovery rate (FDR) as an error criterion in multiple testing, but is only well-defined in Bayesian…

Statistics Theory · Mathematics 2025-02-25 Daniel Xiang , Jake A. Soloff , William Fithian

The positive false discovery rate (pFDR) is a useful overall measure of errors for multiple hypothesis testing, especially when the underlying goal is to attain one or more discoveries. Control of pFDR critically depends on how much…

Statistics Theory · Mathematics 2011-11-09 Zhiyi Chi

To find interesting items in genome-wide association studies or next generation sequencing data, a crucial point is to design powerful false discovery rate (FDR) controlling procedures that suitably combine discrete tests (typically…

Statistics Theory · Mathematics 2017-09-18 Sebastian Döhler , Guillermo Durand , Etienne Roquain

When hypotheses are tested in a stream and real-time decision-making is needed, online sequential hypothesis testing procedures are needed. Furthermore, these hypotheses are commonly partitioned into groups by their nature. For example, the…

Methodology · Statistics 2025-06-05 Runqiu Wang , Ran Dai

With the rapid growth of crowdsourcing platforms it has become easy and relatively inexpensive to collect a dataset labeled by multiple annotators in a short time. However due to the lack of control over the quality of the annotators, some…

Machine Learning · Statistics 2016-06-17 Qianqian Xu , Jiechao Xiong , Xiaochun Cao , Yuan Yao

Identifying areas where the signal is prominent is an important task in image analysis, with particular applications in brain mapping. In this work, we develop confidence regions for spatial excursion sets above and below a given level. We…

Methodology · Statistics 2025-04-18 Howon Ryu , Thomas Maullin-Sapey , Armin Schwartzman , Samuel Davenport

Testing composite null hypotheses arises in various applications, such as mediation and replicability analyses. The problem becomes more challenging in high-throughput experiments where tens of thousands of features are examined…

Methodology · Statistics 2025-04-29 Pengfei Lyu , Xianyang Zhang , Hongyuan Cao

In many applications, the process of identifying a specific feature of interest often involves testing multiple hypotheses for their joint statistical significance. Examples include mediation analysis which simultaneously examines the…

Methodology · Statistics 2023-05-30 Linsui Deng , Kejun He , Xianyang Zhang

The topological gap protocol (TGP) is a statistical test designed to identify a topological phase with high confidence and without human bias. It is used to determine a promising parameter regime for operating topological qubits. The…

Mesoscale and Nanoscale Physics · Physics 2025-04-21 Morteza Aghaee , Zulfi Alam , Mariusz Andrzejczuk , Andrey E. Antipov , Mikhail Astafev , Amin Barzegar , Bela Bauer , Jonathan Becker , Umesh Kumar Bhaskar , Alex Bocharov , Srini Boddapati , David Bohn , Jouri Bommer , Leo Bourdet , Samuel Boutin , Benjamin J. Chapman , Sohail Chatoor , Anna Wulff Christensen , Patrick Codd , William S. Cole , Paul Cooper , Fabiano Corsetti , Ajuan Cui , Andreas Ekefjärd , Saeed Fallahi , Luca Galletti , Geoff Gardner , Deshan Govender , Flavio Griggio , Ruben Grigoryan , Sebastian Grijalva , Sergei Gronin , Jan Gukelberger , Marzie Hamdast , Esben Bork Hansen , Sebastian Heedt , Samantha Ho , Laurens Holgaard , Kevin Van Hoogdalem , Jinnapat Indrapiromkul , Henrik Ingerslev , Lovro Ivancevic , Thomas Jensen , Jaspreet Jhoja , Jeffrey Jones , Konstantin V. Kalashnikov , Ray Kallaher , Rachpon Kalra , Farhad Karimi , Torsten Karzig , Maren Elisabeth Kloster , Christina Knapp , Jonne Koski , Pasi Kostamo , Tom Laeven , Gijs de Lange , Thorvald Larsen , Jason Lee , Kyunghoon Lee , Grant Leum , Kongyi Li , Tyler Lindemann , Matthew Looij , Marijn Lucas , Roman Lutchyn , Morten Hannibal Madsen , Nash Madulid , Michael Manfra , Signe Brynold Markussen , Esteban Martinez , Marco Mattila , Robert McNeil , Ryan V. Mishmash , Gopakumar Mohandas , Christian Mollgaard , Michiel de Moor , Trevor Morgan , George Moussa , Chetan Nayak , William Hvidtfelt Padkær Nielsen , Jens Hedegaard Nielsen , Mike Nystrom , Eoin O'Farrell , Keita Otani , Karl Petersson , Luca Petit , Dima Pikulin , Mohana Rajpalke , Alejandro Alcaraz Ramirez , Katrine Rasmussen , David Razmadze , Yuan Ren , Ken Reneris , Ivan A. Sadovskyy , Lauri Sainiemi , Juan Carlos Estrada Saldaña , Irene Sanlorenzo , Emma Schmidgall , Cristina Sfiligoj , Sarat Sinha , Thomas Soerensen , Patrick Sohr , Tomaš Stankevič , Lieuwe Stek , Eric Stuppard , Henri Suominen , Judith Suter , Sam Teicher , Nivetha Thiyagarajah , Raj Tholapi , Mason Thomas , Emily Toomey , Josh Tracy , Michelle Turley , Shivendra Upadhyay , Ivan Urban , Dmitrii V. Viazmitinov , Dominik Vogel , John Watson , Alex Webster , Joseph Weston , Georg W. Winkler , David J. Van Woerkom , Brian Paquelet Wütz , Chung Kai Yang , Emrah Yucelen , Jesús Herranz Zamorano , Roland Zeisel , Guoji Zheng , Justin Zilke

How to weigh the Benjamini-Hochberg procedure? In the context of multiple hypothesis testing, we propose a new step-wise procedure that controls the false discovery rate (FDR) and we prove it to be more powerful than any weighted…

Statistics Theory · Mathematics 2009-07-13 Etienne Roquain , Mark Van De Wiel

Integrating data from multiple sources expands research opportunities at low cost. However, due to different data collection processes and privacy constraints, unique identifiers are unavailable. Record Linkage (RL) algorithms address this…

Methodology · Statistics 2025-10-07 Kayané Robach , Michel H. Hof , Mark A. van de Wiel