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The problem of multiple hypothesis testing arises when there are more than one hypothesis to be tested simultaneously for statistical significance. This is a very common situation in many data mining applications. For instance, assessing…

Machine Learning · Statistics 2009-06-30 Sami Hanhijärvi , Kai Puolamäki , Gemma C. Garriga

In the context of multiple hypotheses testing, the proportion $\pi_0$ of true null hypotheses in the pool of hypotheses to test often plays a crucial role, although it is generally unknown a priori. A testing procedure using an implicit or…

Statistics Theory · Mathematics 2009-02-17 Gilles Blanchard , Etienne Roquain

As big data continues to grow, statistical inference for multivariate functional data (MFD) has become crucial. Although recent advancements have been made in testing the equality of mean functions, research on testing linear hypotheses for…

Methodology · Statistics 2025-04-07 Tianming Zhu

Standard multiple testing procedures are designed to report a list of discoveries, or suspected false null hypotheses, given the hypotheses' p-values or test scores. Recently there has been a growing interest in enhancing such procedures by…

Methodology · Statistics 2025-10-29 Jack Freestone , William Stafford Noble , Uri Keich

Empirical research in the social and medical sciences frequently involves testing multiple hypotheses simultaneously, increasing the risk of false positives due to chance. Classical multiple testing procedures, such as the Bonferroni…

Econometrics · Economics 2025-07-29 Sebastian Calonico , Sebastian Galiani

In this paper, we address the normal mean inference problem, which involves testing multiple means of normal random variables with heteroscedastic variances. Most existing empirical Bayes methods for this setting are developed under…

Methodology · Statistics 2026-01-01 Kwangok Seo , Johan Lim , Kaiwen Wang , Dohwan Park , Shota Katayama , Xinlei Wang

We study asymptotic properties of Bayesian multiple testing procedures and provide sufficient conditions for strong consistency under general dependence structure. We also consider a novel Bayesian multiple testing procedure and associated…

Statistics Theory · Mathematics 2020-05-15 Noirrit K. Chandra , Sourabh Bhattacharya

In this paper, our interest is in the problem of simultaneous hypothesis testing when the test statistics corresponding to the individual hypotheses are possibly correlated. Specifically, we consider the case when the test statistics…

Statistics Theory · Mathematics 2019-01-14 Anupam Kundu , Subir Kumar Bhandari

Identifying informative predictors in a high dimensional regression model is a critical step for association analysis and predictive modeling. Signal detection in the high dimensional setting often fails due to the limited sample size. One…

Methodology · Statistics 2020-04-08 Molei Liu , Yin Xia , Kelly Cho , Tianxi Cai

This paper proposes self-normalized tests for multistep conditional predictive ability in forecast comparison. By normalizing the sample mean of the transformed loss differential using functionals of its cumulative sum (CUSUM) process,…

Statistics Theory · Mathematics 2026-05-11 Qitong Chen , Shuwen Lai

While there exists several inferential methods for analyzing functional data in factorial designs, there is a lack of statistical tests that are valid (i) in general designs, (ii) under non-restrictive assumptions on the data generating…

Methodology · Statistics 2023-06-28 Merle Munko , Marc Ditzhaus , Markus Pauly , Łukasz Smaga , Jin-Ting Zhang

We consider large-scale studies in which thousands of significance tests are performed simultaneously. In some of these studies, the multiple testing procedure can be severely biased by latent confounding factors such as batch effects and…

Methodology · Statistics 2016-06-21 Jingshu Wang , Qingyuan Zhao , Trevor Hastie , Art B. Owen

In applied research, it is often sensible to account for one or several covariates when testing for differences between multivariate means of several groups. However, the "classical" parametric multivariate analysis of covariance (MANCOVA)…

Methodology · Statistics 2020-04-28 Georg Zimmermann , Markus Pauly , Arne C. Bathke

When testing many hypotheses, often we do not have strong expectations about the directions of the effects. In some situations however, the alternative hypotheses are that the parameters lie in a certain direction or interval, and it is in…

Methodology · Statistics 2026-03-02 Jesse Hemerik

Randomization testing is a fundamental method in statistics, enabling inferential tasks such as testing for (conditional) independence of random variables, constructing confidence intervals in semiparametric location models, and…

Methodology · Statistics 2023-03-21 Yash Nair , Lucas Janson

Recently, a growing body of research has focused on either optimizing CTR model architectures to better model feature interactions or refining training objectives to aid parameter learning, thereby achieving better predictive performance.…

Machine Learning · Computer Science 2026-05-27 Moyu Zhang , Yun Chen , Yujun Jin , Jinxin Hu , Yu Zhang , Xiaoyi Zeng

Controlling False Discovery Rate (FDR) while leveraging the side information of multiple hypothesis testing is an emerging research topic in modern data science. Existing methods rely on the test-level covariates while ignoring metrics…

Machine Learning · Statistics 2022-10-10 Lin Qiu , Nils Murrugarra-Llerena , Vítor Silva , Lin Lin , Vernon M. Chinchilli

In many large scale multiple testing applications, the hypotheses often have a known graphical structure, such as gene ontology in gene expression data. Exploiting this graphical structure in multiple testing procedures can improve power as…

Methodology · Statistics 2018-12-04 Wenge Guo , Gavin Lynch , Joseph P. Romano

The past decade has witnessed a surge of endeavors in statistical inference for high-dimensional sparse regression, particularly via de-biasing or relaxed orthogonalization. Nevertheless, these techniques typically require a more stringent…

Statistics Theory · Mathematics 2021-11-29 Yang Li , Zemin Zheng , Jia Zhou , Ziwei Zhu

This paper tackles the problem of detecting abrupt changes in the mean of a heteroscedastic signal by model selection, without knowledge on the variations of the noise. A new family of change-point detection procedures is proposed, showing…

Methodology · Statistics 2011-02-01 Sylvain Arlot , Alain Celisse