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Identification of key variables such as medications, diseases, relations from health records and clinical notes has a wide range of applications in the clinical domain. n2c2 2022 provided shared tasks on challenges in natural language…

Computation and Language · Computer Science 2025-07-01 Shouvon Sarker , Xishuang Dong , Lijun Qian

OpenNotes enables patients to access EHR notes, but medical jargon can hinder comprehension. To improve understanding, we evaluated closed- and open-source LLMs for extracting and prioritizing key medical terms using prompting, fine-tuning,…

Computation and Language · Computer Science 2026-05-08 Won Seok Jang , Sharmin Sultana , Zonghai Yao , Hieu Tran , Zhichao Yang , Sunjae Kwon , Hong Yu

Attention-based models have become the leading approach in modeling medical language for Natural Language Processing (NLP) in clinical notes. These models outperform traditional techniques by effectively capturing contextual representations…

Computation and Language · Computer Science 2025-09-26 Tariq Abdul-Quddoos , Xishuang Dong , Lijun Qian

Clinical trials are a critical component of evaluating the effectiveness of new medical interventions and driving advancements in medical research. Therefore, timely enrollment of patients is crucial to prevent delays or premature…

Information Retrieval · Computer Science 2023-06-12 Georgios Peikos , Symeon Symeonidis , Pranav Kasela , Gabriella Pasi

With the advent of large language models (LLMs), there has been growing interest in exploring their potential for medical applications. This research aims to investigate the ability of LLMs, specifically ChatGPT, in the context of…

Computation and Language · Computer Science 2024-02-27 Zhaoyue Sun , Gabriele Pergola , Byron C. Wallace , Yulan He

Electronic Health Records are large repositories of valuable clinical data, with a significant portion stored in unstructured text format. This textual data includes clinical events (e.g., disorders, symptoms, findings, medications and…

Computation and Language · Computer Science 2024-09-02 Shubham Agarwal , Thomas Searle , Mart Ratas , Anthony Shek , James Teo , Richard Dobson

Participant recruitment based on unstructured medical texts such as clinical notes and radiology reports has been a challenging yet important task for the cohort establishment in clinical research. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2023-07-24 Zihan Guan , Zihao Wu , Zhengliang Liu , Dufan Wu , Hui Ren , Quanzheng Li , Xiang Li , Ninghao Liu

The mental disorder of online users is determined using social media posts. The major challenge in this domain is to avail the ethical clearance for using the user generated text on social media platforms. Academic re searchers identified…

Computation and Language · Computer Science 2022-11-09 Gunjan Ansari , Muskan Garg , Chandni Saxena

Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

Computation and Language · Computer Science 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

An important issue impacting healthcare is a lack of available experts. Machine learning (ML) models could resolve this by aiding in diagnosing patients. However, creating datasets large enough to train these models is expensive. We…

Computation and Language · Computer Science 2024-05-14 Chancellor R. Woolsey , Prakash Bisht , Joshua Rothman , Gondy Leroy

An accurate and detailed account of patient medications, including medication changes within the patient timeline, is essential for healthcare providers to provide appropriate patient care. Healthcare providers or the patients themselves…

Recent advancements in large language models (LLMs) have led to the development of highly potent models like OpenAI's ChatGPT. These models have exhibited exceptional performance in a variety of tasks, such as question answering, essay…

Computation and Language · Computer Science 2023-04-12 Ruixiang Tang , Xiaotian Han , Xiaoqian Jiang , Xia Hu

Previous studies reveal that Electronic Health Records (EHR), which have been widely adopted in the U.S. to allow patients to access their personal medical information, do not have high readability to patients due to the prevalence of…

Computation and Language · Computer Science 2024-08-13 Jung Hoon Lim , Sunjae Kwon , Zonghai Yao , John P. Lalor , Hong Yu

The extraction of critical patient information from Electronic Health Records (EHRs) poses significant challenges due to the complexity and unstructured nature of the data. Traditional machine learning approaches often fail to capture…

Computation and Language · Computer Science 2025-09-03 Zhimeng Luo , Abhibha Gupta , Adam Frisch , Daqing He

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR…

Machine Learning · Computer Science 2025-10-07 Sarah C. Lotspeich , Abbey Collins , Brian J. Wells , Ashish K. Khanna , Joseph Rigdon , Lucy D'Agostino McGowan

Large-scale language models (LLMs) like ChatGPT have demonstrated impressive abilities in generating responses based on human instructions. However, their use in the medical field can be challenging due to their lack of specific, in-depth…

Computation and Language · Computer Science 2025-02-25 Yubo Wang , Xueguang Ma , Wenhu Chen

Objective: Electronic health records (EHR) are widely available to complement administrative data-based disease surveillance and healthcare performance evaluation. Defining conditions from EHR is labour-intensive and requires extensive…

Computation and Language · Computer Science 2025-04-09 Jie Pan , Seungwon Lee , Cheligeer Cheligeer , Elliot A. Martin , Kiarash Riazi , Hude Quan , Na Li

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan
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