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Temporal point processes (TPP) are probabilistic generative models for continuous-time event sequences. Neural TPPs combine the fundamental ideas from point process literature with deep learning approaches, thus enabling construction of…

Machine Learning · Computer Science 2021-08-26 Oleksandr Shchur , Ali Caner Türkmen , Tim Januschowski , Stephan Günnemann

Peptide Optimization is a highly complex problem and it takes very long time of computation. This optimization process uses many software applications in a cluster running GNU/Linux Operating System that perform special tasks. The…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-12-05 Andias Wira-Alam

Many physical and biological processes are stochastic in nature. Computational models and simulations of such processes are a mathematical and computational challenge. The basic stochastic simulation algorithm was published by D. Gillespie…

Quantitative Methods · Quantitative Biology 2009-11-13 Azi Lipshtat

The current landscape of scientific research is widely based on modeling and simulation, typically with complexity in the simulation's flow of execution and parameterization properties. Execution flows are not necessarily straightforward…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-26 Eduardo Ponce , Brittany Stephenson , Suzanne Lenhart , Judy Day , Gregory D. Peterson

Spatiotemporal dynamics models are fundamental for various domains, from heat propagation in materials to oceanic and atmospheric flows. However, currently available neural network-based spatiotemporal modeling approaches fall short when…

Machine Learning · Computer Science 2025-02-11 Valerii Iakovlev , Harri Lähdesmäki

The present paper deals with the problem of improving the efficiency of large scale turbulent flow simulations. The high-fidelity methods for modelling turbulent flows become available for a wider range of applications thanks to the…

Computational Physics · Physics 2018-04-10 Boris Krasnopolsky

We discuss computational superstructures that, using repeated, appropriately initialized short calls, enable temporal process simulators to perform alternative tasks such as fixed point computation, stability analysis and projective…

Optimization and Control · Mathematics 2025-10-20 C. I. Siettos , C. C. Pantelides , I. G. Kevrekidis

Classical Molecular Dynamics (MD) simulations provide insight on the properties of many soft-matter systems. In some situations it is interesting to model the creation of chemical bonds, a process that is not part of the MD framework. In…

Soft Condensed Matter · Physics 2015-04-02 Pierre de Buyl , Erik Nies

Classical methods to simulate quantum systems are not only a key element of the physicist's toolkit for studying many-body models but are also increasingly important for verifying and challenging upcoming quantum computers. Pauli…

Quantum Physics · Physics 2025-05-29 Manuel S. Rudolph , Tyson Jones , Yanting Teng , Armando Angrisani , Zoë Holmes

We investigate applications of deep neural networks to a point process having an intensity with mixing covariates processes as input. Our generic model includes Cox-type models and marked point processes as well as multivariate point…

Statistics Theory · Mathematics 2025-04-23 Yoshihiro Gyotoku , Ioane Muni Toke , Nakahiro Yoshida

We introduce Simulation Streams, a programming paradigm designed to efficiently control and leverage Large Language Models (LLMs) for complex, dynamic simulations and agentic workflows. Our primary goal is to create a minimally interfering…

Artificial Intelligence · Computer Science 2025-02-03 Peter Sunehag , Joel Z. Leibo

Model checkpoints are critical Deep Learning (DL) artifacts that enable fault tolerance for training and downstream applications, such as inference. However, writing checkpoints to persistent storage, and other I/O aspects of DL training,…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-21 Guanhua Wang , Olatunji Ruwase , Bing Xie , Yuxiong He

Self-exciting spatio-temporal point process models predict the rate of events as a function of space, time, and the previous history of events. These models naturally capture triggering and clustering behavior, and have been widely used in…

Methodology · Statistics 2018-08-14 Alex Reinhart

We consider the problem of locating a jump discontinuity (change-point) in a smooth parametric regression model with a bounded covariate. It is assumed that one can sample the covariate at different values and measure the corresponding…

Statistics Theory · Mathematics 2009-08-14 Yan Lan , Moulinath Banerjee , George Michailidis

Spatio-temporal Hawkes point processes are a particularly interesting class of stochastic point processes for modeling self-exciting behavior, in which the occurrence of one event increases the probability of other events occurring. These…

Computation · Statistics 2025-11-19 Alba Bernabeu , Jorge Mateu

Molecular dynamics simulations hold great promise for providing insight into the microscopic behavior of complex molecular systems. However, their effectiveness is often constrained by long timescales associated with rare events. Enhanced…

Computational Physics · Physics 2026-03-03 Kai Zhu , Enrico Trizio , Jintu Zhang , Renling Hu , Linlong Jiang , Tingjun Hou , Luigi Bonati

A number of different multiscale methods have been developed as a robust alternative to upscaling and as a means for accelerated reservoir simulation of high-resolution geomodels. In their basic setup, multiscale methods use a restriction…

Numerical Analysis · Mathematics 2020-01-07 Øystein Strengehagen Klemetsdal , Olav Møyner , Knut-Andreas Lie

In the setting of polynomial jump-diffusion dynamics, we provide an explicit formula for computing correlators, namely, cross-moments of the process at different time points along its path. The formula appears as a linear combination of…

Probability · Mathematics 2021-04-26 Fred Espen Benth , Silvia Lavagnini

Integrating computational fluid dynamics (CFD) software into optimization and machine-learning frameworks is hampered by the rigidity of classic computational languages and the slow performance of more flexible high-level languages.…

Fluid Dynamics · Physics 2023-04-18 Gabriel D. Weymouth , Bernat Font

We propose a new route to accelerate molecular dynamics through the use of velocity jump processes allowing for an adaptive time-step specific to each atom-atom pair (2-body) interactions. We start by introducing the formalism of the new…

Chemical Physics · Physics 2021-03-30 Pierre Monmarché , Jérémy Weisman , Louis Lagardère , Jean-Philip Piquemal