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Homophily is a graph property describing the tendency of edges to connect similar nodes; the opposite is called heterophily. It is often believed that heterophilous graphs are challenging for standard message-passing graph neural networks…

Social and Information Networks · Computer Science 2024-04-17 Oleg Platonov , Denis Kuznedelev , Artem Babenko , Liudmila Prokhorenkova

A CIS graph is a graph in which every maximal stable set and every maximal clique intersect. A graph is well-covered if all its maximal stable sets are of the same size, co-well-covered if its complement is well-covered, and…

Combinatorics · Mathematics 2016-08-08 Edward Dobson , Ademir Hujdurović , Martin Milanič , Gabriel Verret

Node classification is a classical graph machine learning task on which Graph Neural Networks (GNNs) have recently achieved strong results. However, it is often believed that standard GNNs only work well for homophilous graphs, i.e., graphs…

Machine Learning · Computer Science 2024-03-05 Oleg Platonov , Denis Kuznedelev , Michael Diskin , Artem Babenko , Liudmila Prokhorenkova

We investigate structural and algorithmic advantages of a directed version of the well-researched class of distance-hereditary graphs. Since the previously defined distance-hereditary digraphs do not permit a recursive structure, we define…

Discrete Mathematics · Computer Science 2021-12-09 Dominique Komander , Carolin Rehs

A split graph is a graph whose vertices can be partitioned into a clique and a stable set. We investigate the combinatorial species of split graphs, providing species-theoretic generalizations of enumerative results due to B\'ina and…

Combinatorics · Mathematics 2019-07-16 Justin M. Troyka

We study a class of growth algorithms for directed graphs that are candidate models for the evolution of genetic regulatory networks. The algorithms involve partial duplication of nodes and their links, together with innovation of new…

Molecular Networks · Quantitative Biology 2007-05-23 D. V. Foster , S. A. Kauffman , J. E. S. Socolar

In mathematical phylogenetics, evolutionary relationships are often represented by trees and networks. The latter are typically used whenever the relationships cannot be adequately described by a tree, which happens when so-called…

Populations and Evolution · Quantitative Biology 2025-12-05 Mirko Wilde , Mareike Fischer

Phylogenetic networks are a type of leaf-labelled, acyclic, directed graph used by biologists to represent the evolutionary history of species whose past includes reticulation events. A phylogenetic network is tree-child if each non-leaf…

Combinatorics · Mathematics 2017-11-27 Magnus Bordewich , Katharina T Huber , Vincent Moulton , Charles Semple

Unigraphs are graphs identifiable up to isomorphism from their degree sequences. Given a class $\mathcal{A}$ of graphs, we define the class of $\mathcal{A}$-unigraphs to be graphs identifiable from degree sequence and membership in…

Combinatorics · Mathematics 2024-06-07 R. Whitman

The inference of gene regulatory networks (GRNs) is a foundational stride towards deciphering the fundamentals of complex biological systems. Inferring a possible regulatory link between two genes can be formulated as a link prediction…

Machine Learning · Computer Science 2025-04-25 Binon Teji , Swarup Roy

Threshold graphs are recursive deterministic network models that have been proposed for describing certain economic and social interactions. One drawback of this graph family is that it has limited generative attachment rules. To mitigate…

Social and Information Networks · Computer Science 2018-05-24 Vida Ravanmehr , Gregory J. Puleo , Sadegh Bolouki , Olgica Milenkovic

Let $G$ be a graph and $A$ be its adjacency matrix. A graph $G$ is invertible if its adjacency matrix $A$ is invertible and the inverse of $G$ is a weighted graph with adjacency matrix $A^{-1}$. A signed graph $(G,\sigma)$ is a weighted…

Combinatorics · Mathematics 2023-03-23 Isaiah Osborne , Dong Ye

Gene innovation is a key mechanism on the evolution and phenotypic diversity of life forms. There is a need for tools able to study gene innovation across an increasingly large number of genomic sequences to maximally capitalise our…

Populations and Evolution · Quantitative Biology 2012-12-18 Inti Pedroso , Mark J. F. Brown , Seirian Sumner

Gene gains and losses have shaped the gene repertoire of species since the universal last common ancestor to species today. Genes in extant species were gained at different historical times via de novo creation of new genes, duplication of…

Populations and Evolution · Quantitative Biology 2018-02-19 Haiming Tang , Paul Thomas , Haoran Xia

Phylogenetic reconstruction aims at finding plausible hypotheses of the evolutionary history of genes or species based on genomic sequence information. The distinction of orthologous genes (genes that having a common ancestry and diverged…

Populations and Evolution · Quantitative Biology 2016-02-29 Marc Hellmuth , Nicolas Wieseke

A graph $G$ realizes the degree sequence $S$ if the degrees of its vertices is $S$. Hakimi gave a necessary and sufficient condition to guarantee that there exists a connected multigraph realizing $S$. Taylor later proved that any connected…

Discrete Mathematics · Computer Science 2018-09-17 Nicolas Bousquet , Arnaud Mary

The complex pattern of presence and absence of many genes across different species provides tantalising clues as to how genes evolved through the processes of gene genesis, gene loss and lateral gene transfer (LGT). The extent of LGT,…

Populations and Evolution · Quantitative Biology 2009-11-09 Leo van Iersel , Charles Semple , Mike Steel

A digraph is attached to any evolution algebra. This graph leads to some new purely algebraic results on this class of algebras and allows for some new natural proofs of known results. Nilpotency of an evolution algebra will be proved to be…

Rings and Algebras · Mathematics 2013-12-18 Alberto Elduque , Alicia Labra

A directed graph $D$ is singly connected if for every ordered pair of vertices $(s,t)$, there is at most one path from $s$ to $t$ in $D$. Graph orientation problems ask, given an undirected graph $G$, to find an orientation of the edges…

Combinatorics · Mathematics 2023-06-06 Tim A. Hartmann , Komal Muluk

Graph Neural Networks (GNNs) have become the de-facto standard tool for modeling relational data. However, while many real-world graphs are directed, the majority of today's GNN models discard this information altogether by simply making…

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