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Deep neural networks for medical image classification often fail to generalize consistently in clinical practice due to violations of the i.i.d. assumption and opaque decision-making. This paper examines interpretability in deep neural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Mohammad Hossein Najafi , Mohammad Morsali , Mohammadreza Pashanejad , Saman Soleimani Roudi , Mohammad Norouzi , Saeed Bagheri Shouraki

Recent developments in Artificial Intelligence (AI) and their applications in critical industries such as healthcare, fin-tech and cybersecurity have led to a surge in research in explainability in AI. Innovative research methods are being…

Artificial Intelligence · Computer Science 2025-08-26 Aoun E Muhammad , Kin-Choong Yow , Nebojsa Bacanin-Dzakula , Muhammad Attique Khan

Artificial Intelligence (AI), and in particular, the explainability thereof, has gained phenomenal attention over the last few years. Whilst we usually do not question the decision-making process of these systems in situations where only…

Artificial Intelligence · Computer Science 2021-01-29 Iena Petronella Derks , Alta de Waal

Background: Despite the current ubiquity of Large Language Models (LLMs) across the medical domain, there is a surprising lack of studies which address their reasoning behaviour. We emphasise the importance of understanding reasoning…

Computation and Language · Computer Science 2025-07-29 Shamus Sim , Tyrone Chen

As artificial intelligence (AI) systems become increasingly complex and ubiquitous, these systems will be responsible for making decisions that directly affect individuals and society as a whole. Such decisions will need to be justified due…

Artificial Intelligence · Computer Science 2018-12-21 Prashan Madumal , Ronal Singh , Joshua Newn , Frank Vetere

Artificial intelligence (AI) is being applied in almost every field. At the same time, the currently dominant deep learning methods are fundamentally black-box systems that lack explanations for their inferences, significantly limiting…

Artificial Intelligence · Computer Science 2025-10-06 Martina Mattioli , Eike Petersen , Aasa Feragen , Marcello Pelillo , Siavash A. Bigdeli

Artificial Intelligence (AI) has become an integral part of modern-day security solutions for its ability to learn very complex functions and handling "Big Data". However, the lack of explainability and interpretability of successful AI…

Artificial Intelligence · Computer Science 2020-02-25 Sheikh Rabiul Islam , William Eberle , Sheikh K. Ghafoor , Ambareen Siraj , Mike Rogers

The question addressed in this paper is: If we present to a user an AI system that explains how it works, how do we know whether the explanation works and the user has achieved a pragmatic understanding of the AI? In other words, how do we…

Artificial Intelligence · Computer Science 2019-02-04 Robert R. Hoffman , Shane T. Mueller , Gary Klein , Jordan Litman

This paper presents ExplainableFold, an explainable AI framework for protein structure prediction. Despite the success of AI-based methods such as AlphaFold in this field, the underlying reasons for their predictions remain unclear due to…

Artificial Intelligence · Computer Science 2023-06-12 Juntao Tan , Yongfeng Zhang

Explainability remains a critical challenge in artificial intelligence (AI) systems, particularly in high stakes domains such as healthcare, finance, and decision support, where users must understand and trust automated reasoning.…

Human-Computer Interaction · Computer Science 2025-08-05 Rukshani Somarathna , Madhawa Perera , Tom Gedeon , Matt Adcock

The field of "explainable artificial intelligence" (XAI) seemingly addresses the desire that decisions of machine learning systems should be human-understandable. However, in its current state, XAI itself needs scrutiny. Popular methods…

Machine Learning · Computer Science 2026-04-09 Stefan Haufe , Rick Wilming , Benedict Clark , Rustam Zhumagambetov , Ahcène Boubekki , Jörg Martin , Danny Panknin

The ability to explain decisions made by AI systems is highly sought after, especially in domains where human lives are at stake such as medicine or autonomous vehicles. While it is often possible to approximate the input-output relations…

Artificial Intelligence · Computer Science 2020-10-15 Daniel C. Elton

Robots assisting humans in complex domains have to represent knowledge and reason at both the sensorimotor level and the social level. The architecture described in this paper couples the non-monotonic logical reasoning capabilities of a…

Robotics · Computer Science 2015-08-04 Zenon Colaco , Mohan Sridharan

Explanations are hypothesized to improve human understanding of machine learning models and achieve a variety of desirable outcomes, ranging from model debugging to enhancing human decision making. However, empirical studies have found…

Artificial Intelligence · Computer Science 2023-05-02 Chacha Chen , Shi Feng , Amit Sharma , Chenhao Tan

The need for transparency of predictive systems based on Machine Learning algorithms arises as a consequence of their ever-increasing proliferation in the industry. Whenever black-box algorithmic predictions influence human affairs, the…

Machine Learning · Computer Science 2020-02-11 Kacper Sokol , Peter Flach

The rapid advancements in artificial intelligence (AI) have revolutionized smart healthcare, driving innovations in wearable technologies, continuous monitoring devices, and intelligent diagnostic systems. However, security, explainability,…

Machine Learning · Computer Science 2024-10-02 Prasenjit Maji , Amit Kumar Mondal , Hemanta Kumar Mondal , Saraju P. Mohanty

In artificial intelligence (AI), the complexity of many models and processes surpasses human understanding, making it challenging to determine why a specific prediction is made. This lack of transparency is particularly problematic in…

Machine Learning · Statistics 2025-06-30 Alexandra Stadler , Werner G. Müller , Radoslav Harman

Conventionally, AI models are thought to trade off explainability for lower accuracy. We develop a training strategy that not only leads to a more explainable AI system for object classification, but as a consequence, suffers no perceptible…

Computer Vision and Pattern Recognition · Computer Science 2020-03-17 Andrea Zunino , Sarah Adel Bargal , Riccardo Volpi , Mehrnoosh Sameki , Jianming Zhang , Stan Sclaroff , Vittorio Murino , Kate Saenko

Recent advancements in artificial intelligence (AI) have facilitated its widespread adoption in primary medical services, addressing the demand-supply imbalance in healthcare. Vision Transformers (ViT) have emerged as state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Tin Lai

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo
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