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We report that a cell-sized water droplet (CWD) with a diameter of several tens of microns can serve as a micro-biochemical reactor. Since the droplet inner surface is covered by a phospholipid layer, it provides an environment similar to…

Biological Physics · Physics 2007-05-23 Masahiko Hase , Ayako Yamada , Tsutomu Hamada , Kenichi Yoshikawa

Programmable materials are desirable for a variety of functional applications that range from biomedical devices, actuators and soft robots to adaptive surfaces and deployable structures. However, current smart materials are often designed…

Inputs to signaling pathways can have complex statistics that depend on the environment and on the behavioral response to previous stimuli. Such behavioral feedback is particularly important in navigation. Successful navigation relies on…

Molecular Networks · Quantitative Biology 2014-12-02 Yann S. Dufour , Xiongfei Fu , Luis Hernandez-Nunez , Thierry Emonet

We describe a general theory for surface-catalyzed bimolecular reactions in responsive nanoreactors, catalytically active nanoparticles coated by a stimuli-responsive 'gating' shell, whose permeability controls the activity of the process.…

Chemical Physics · Physics 2018-01-29 Rafael Roa , Won Kyu Kim , Matej Kanduc , Joachim Dzubiella , Stefano Angioletti-Uberti

Superresolution microscopy has become a powerful tool to investigate the internal structure of complex colloidal and polymeric systems, such as microgels, at the nanometer scale. The ability to monitor microgels response to temperature…

Biological systems use neural circuits to integrate input information and produce outputs. Synaptic convergence, where multiple neurons converge their inputs onto a single downstream neuron, is common in natural neural circuits. However,…

Mesoscale and Nanoscale Physics · Physics 2026-02-04 Wendy Otieno , Alex Gabbitas , Debi Pattnaik , Pavel Borisov , Sergey Savel'ev , Alexander G. Balanov

Chemical communication, response, and feedback are key requirements for the function of adaptive materials with life-like properties. However, how communication on the single cell-level impacts the collective structural, dynamical and…

Soft Condensed Matter · Physics 2025-09-22 Nils Göth , Joachim Dzubiella

The stochastic FitzHugh-Nagumo model with time delayed-feedback is often studied in excitable regime to demonstrate the time-delayed control of coherence resonance. Here, we show that the impact of time-delayed feedback in the…

Adaptation and Self-Organizing Systems · Physics 2023-05-24 Vladimir V. Semenov , Andrei V. Bukh , Nadezhda Semenova

Chalcogenide phase change materials (PCMs) have been extensively applied in data storage, and they are now being proposed for high resolution displays, holographic displays, reprogrammable photonics, and all-optical neural networks. These…

Optics · Physics 2023-08-09 Yunzheng Wang , Jing Ning , Li Lu , Michel Bosman , Robert E. Simpson

The influence of time delay in systems of two coupled excitable neurons is studied in the framework of the FitzHugh-Nagumo model. Time-delay can occur in the coupling between neurons or in a self-feedback loop. The stochastic…

Pattern Formation and Solitons · Physics 2009-11-13 E. Schoell , G. Hiller , P. Hoevel , M. A. Dahlem

We investigate the creation and control of emergent collective behavior and quantum correlations using feedback in an emitter-waveguide system using a minimal model. Employing homodyne detection of photons emitted from a laser-driven…

Quantum Physics · Physics 2021-09-29 Giuseppe Buonaiuto , Federico Carollo , Beatriz Olmos , Igor Lesanovsky

Adaptation of the chemotaxis sensory pathway of the bacterium Escherichia coli is integral for detecting chemicals over a wide range of background concentrations, ultimately allowing cells to swim towards sources of attractant and away from…

Cell Behavior · Quantitative Biology 2015-05-18 Diana Clausznitzer , Olga Oleksiuk , Linda Lovdok , Victor Sourjik , Robert G. Endres

Porous media, while ubiquitous across many engineering disciplines, is inherently difficult to characterize due to their innate stochasticity and heterogeneity. The key for predicting porous material behavior comes down to the structuring…

Soft Condensed Matter · Physics 2024-03-26 Winston Lindqwister , Manolis Veveakis , Martin Lesueur

Thermo-responsive hydrogels are smart materials that rapidly switch between hydrophilic (swollen) and hydrophobic (shrunken) states when heated past a threshold temperature, resulting in order-of-magnitude changes in gel volume. Modelling…

Fluid Dynamics · Physics 2025-05-14 Joseph J. Webber , Thomas D. Montenegro-Johnson

We present a new simulation technique to study systems of polymers functionalized by reactive sites that bind/unbind forming reversible linkages. Functionalized polymers feature self-assembly and responsive properties that are unmatched by…

Soft Condensed Matter · Physics 2018-04-18 Bernardo Oyarzún , Bortolo Matteo Mognetti

How pattern and form are generated in a reproducible manner during embryogenesis remains poorly understood. Intestinal organoid morphogenesis involves a number of mechanochemical regulators, including cell-type specific cytoskeletal forces…

Tissues and Organs · Quantitative Biology 2024-04-01 Shi-Lei Xue , Qiutan Yang , Prisca Liberali , Edouard Hannezo

The mechanical and electrical response of acoustophoretic microfluidic devices attached to an ac-voltage-driven piezoelectric transducer is studied by means of numerical simulations. The governing equations are formulated in a variational…

Fluid Dynamics · Physics 2017-06-07 Fabio Garofalo , Thomas Laurell , Henrik Bruus

In various neurological disorders spatio-temporal excitation patterns constitute examples of excitable behavior emerging from pathological pathways. During migraine, seizure, and stroke an initially localized pathological state can…

Pattern Formation and Solitons · Physics 2007-09-27 Markus A. Dahlem , Felix M. Schneider , Eckehard Schoell

A key problem toward the use of microorganisms as bio-factories is reaching and maintaining cellular communities at a desired density and composition so that they can efficiently convert their biomass into useful compounds. Promising…

Systems and Control · Electrical Eng. & Systems 2023-12-18 Sara Maria Brancato , Davide Salzano , Francesco De Lellis , Davide Fiore , Giovanni Russo , Mario di Bernardo

Hydrogels are soft materials engineered to suit a multitude of applications that exploit their tunable mechanochemical properties. Dynamic hydrogels employing noncovalent, physically crosslinked networks dominated by either enthalpic or…

Soft Condensed Matter · Physics 2023-11-28 Samya Sen , Anthony C. Yu , Changxin Dong , Andrea I. D'Aquino , Eric A. Appel
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