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Medical data poses a daunting challenge for AI algorithms: it exists in many different modalities, experiences frequent distribution shifts, and suffers from a scarcity of examples and labels. Recent advances, including transformers and…

Foundation models have emerged as a powerful approach for processing electronic health records (EHRs), offering flexibility to handle diverse medical data modalities. In this study, we present a comprehensive benchmark that evaluates the…

Machine Learning · Computer Science 2025-07-22 Kunyu Yu , Rui Yang , Jingchi Liao , Siqi Li , Huitao Li , Irene Li , Yifan Peng , Rishikesan Kamaleswaran , Nan Liu

Recent deep learning research based on Transformer model architectures has demonstrated state-of-the-art performance across a variety of domains and tasks, mostly within the computer vision and natural language processing domains. While…

Machine Learning · Computer Science 2021-11-11 Benjamin Shickel , Patrick J. Tighe , Azra Bihorac , Parisa Rashidi

We introduce PathBench-MIL, an open-source AutoML and benchmarking framework for multiple instance learning (MIL) in histopathology. The system automates end-to-end MIL pipeline construction, including preprocessing, feature extraction, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Siemen Brussee , Pieter A. Valkema , Jurre A. J. Weijer , Thom Doeleman , Anne M. R. Schrader , Jesper Kers

Commonly, AI or machine learning (ML) models are evaluated on benchmark datasets. This practice supports innovative methodological research, but benchmark performance can be poorly correlated with performance in real-world applications -- a…

Machine Learning · Computer Science 2024-06-18 Olivier Binette , Jerome P. Reiter

In critical decision support systems based on medical imaging, the reliability of AI-assisted decision-making is as relevant as predictive accuracy. Although deep learning models have demonstrated significant accuracy, they frequently…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Hua Xu , Julián D. Arias-Londoño , Juan I. Godino-Llorente

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

Methodology · Statistics 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky

In recent times, machine learning (ML) and artificial intelligence (AI) based systems have evolved and scaled across different industries such as finance, retail, insurance, energy utilities, etc. Among other things, they have been used to…

Machine Learning · Computer Science 2019-10-02 Akshay Arora , Arun Nethi , Priyanka Kharat , Vency Verghese , Grant Jenkins , Steve Miff , Vikas Chowdhry , Xiao Wang

Machine-learning (ML) models in flow cytometry have the potential to reduce error rates, increase reproducibility, and boost the efficiency of clinical labs. While numerous ML models for flow cytometry data have been proposed, few studies…

Clinical trials are conducted to test the effectiveness and safety of potential drugs in humans for regulatory approval. Machine learning (ML) has recently emerged as a new tool to assist in clinical trials. Despite this progress, there…

Artificial Intelligence · Computer Science 2023-10-06 Zifeng Wang , Brandon Theodorou , Tianfan Fu , Cao Xiao , Jimeng Sun

Machine learning (ML) holds great promise in transforming healthcare. While published studies have shown the utility of ML models in interpreting medical imaging examinations, these are often evaluated under laboratory settings. The…

Medical image analysis using deep learning frameworks has advanced healthcare by automating complex tasks, but many existing frameworks lack flexibility, modularity, and user-friendliness. To address these challenges, we introduce Yucca, an…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Sebastian Nørgaard Llambias , Julia Machnio , Asbjørn Munk , Jakob Ambsdorf , Mads Nielsen , Mostafa Mehdipour Ghazi

While existing critical care EHR datasets such as MIMIC and eICU have enabled significant advances in clinical AI research, the CRITICAL dataset opens new frontiers by providing extensive scale and diversity -- containing 1.95 billion…

Machine Learning · Computer Science 2025-09-24 Xiaolong Luo , Michael Lingzhi Li

Despite the critical importance of the medical domain in Deep Learning, most of the research in this area solely focuses on training models in static environments. It is only in recent years that research has begun to address dynamic…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Marina Ceccon , Davide Dalle Pezze , Alessandro Fabris , Gian Antonio Susto

This research addresses the challenges of handling unbalanced datasets for binary classification tasks. In such scenarios, standard evaluation metrics are often biased by the disproportionate representation of the minority class. Conducting…

Background: Hypertensive kidney disease (HKD) patients in intensive care units (ICUs) face high short-term mortality, but tailored risk prediction tools are lacking. Early identification of high-risk individuals is crucial for clinical…

Machine Learning · Computer Science 2025-07-28 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Minoo Ahmadi , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Notorious for its 70-80% recurrence rate, Non-muscle-invasive Bladder Cancer (NMIBC) imposes a significant human burden and is one of the costliest cancers to manage. Current tools for predicting NMIBC recurrence rely on scoring systems…

Machine Learning · Computer Science 2024-12-23 Saram Abbas , Rishad Shafik , Naeem Soomro , Rakesh Heer , Kabita Adhikari

Patient monitoring is vital in all stages of care. We here report the development and validation of ICU length of stay and mortality prediction models. The models will be used in an intelligent ICU patient monitoring module of an…

Machine Learning · Computer Science 2021-05-11 Khalid Alghatani , Nariman Ammar , Abdelmounaam Rezgui , Arash Shaban-Nejad
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