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Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

We introduce LLMD, a large language model designed to analyze a patient's medical history based on their medical records. Along with domain knowledge, LLMD is trained on a large corpus of records collected over time and across facilities,…

The extraction of critical patient information from Electronic Health Records (EHRs) poses significant challenges due to the complexity and unstructured nature of the data. Traditional machine learning approaches often fail to capture…

Computation and Language · Computer Science 2025-09-03 Zhimeng Luo , Abhibha Gupta , Adam Frisch , Daqing He

Drug discovery is a critical task in biomedical natural language processing (NLP), yet explainable drug discovery remains underexplored. Meanwhile, large language models (LLMs) have shown remarkable abilities in natural language…

Computation and Language · Computer Science 2025-02-28 Kai Zhang , Rui Zhu , Shutian Ma , Jingwei Xiong , Yejin Kim , Fabricio Murai , Xiaozhong Liu

Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

We present a systematic study of medical-domain interpretability in Large Language Models (LLMs). We study how the LLMs both represent and process medical knowledge through four different interpretability techniques: (1) UMAP projections of…

Machine Learning · Computer Science 2026-02-24 Razvan Marinescu , Victoria-Elisabeth Gruber , Diego Fajardo

Recent breakthroughs in large language modeling have facilitated rigorous exploration of their application in diverse tasks related to tabular data modeling, such as prediction, tabular data synthesis, question answering, and table…

Due to an exponential increase in published research articles, it is impossible for individual scientists to read all publications, even within their own research field. In this work, we investigate the use of large language models (LLMs)…

Large Language Models (LLMs) have shown to be capable of various tasks, yet their capability in interpreting and reasoning over tabular data remains an underexplored area. In this context, this study investigates from three core…

Computation and Language · Computer Science 2023-12-29 Tianyang Liu , Fei Wang , Muhao Chen

Recent large language models (LLMs) have demonstrated remarkable prediction performance for a growing array of tasks. However, their proliferation into high-stakes domains (e.g. medicine) and compute-limited settings has created a…

Artificial Intelligence · Computer Science 2023-12-05 Chandan Singh , Armin Askari , Rich Caruana , Jianfeng Gao

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

Information Retrieval · Computer Science 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

We propose a novel framework that leverages large language models (LLMs) to guide the rank selection in tensor network models for higher-order data analysis. By utilising the intrinsic reasoning capabilities and domain knowledge of LLMs,…

Machine Learning · Computer Science 2024-10-15 Giorgos Iacovides , Wuyang Zhou , Danilo Mandic

The introduction of Large Language Models (LLMs) has advanced data representation and analysis, bringing significant progress in their use for medical questions and answering. Despite these advancements, integrating tabular data, especially…

Computation and Language · Computer Science 2024-09-23 Yanjun Gao , Skatje Myers , Shan Chen , Dmitriy Dligach , Timothy A Miller , Danielle Bitterman , Matthew Churpek , Majid Afshar

Motivation: Patient-generated text contains critical information about patients' lived experiences, social circumstances, and engagement in care, including factors that strongly influence adherence, care coordination, and health equity.…

Computation and Language · Computer Science 2026-03-09 Samah Fodeh , Linhai Ma , Ganesh Puthiaraju , Srivani Talakokkul , Afshan Khan , Ashley Hagaman , Sarah Lowe , Aimee Roundtree

Recent development in large language models (LLMs) has demonstrated impressive domain proficiency on unstructured textual or multi-modal tasks. However, despite with intrinsic world knowledge, their application on structured tabular data…

Computation and Language · Computer Science 2025-03-03 Jiahuan Yan , Jintai Chen , Chaowen Hu , Bo Zheng , Yaojun Hu , Jimeng Sun , Jian Wu

Recovering the structure of causal graphical models from observational data is an essential yet challenging task for causal discovery in scientific scenarios. Domain-specific causal discovery usually relies on expert validation or prior…

Artificial Intelligence · Computer Science 2025-08-27 Taiyu Ban , Lyuzhou Chen , Derui Lyu , Xiangyu Wang , Qinrui Zhu , Qiang Tu , Huanhuan Chen

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

We introduce TableLLM, a robust large language model (LLM) with 8 billion parameters, purpose-built for proficiently handling tabular data manipulation tasks, whether they are embedded within documents or spreadsheets, catering to…

Computation and Language · Computer Science 2025-02-18 Xiaokang Zhang , Sijia Luo , Bohan Zhang , Zeyao Ma , Jing Zhang , Yang Li , Guanlin Li , Zijun Yao , Kangli Xu , Jinchang Zhou , Daniel Zhang-Li , Jifan Yu , Shu Zhao , Juanzi Li , Jie Tang

The advent of Large Language Models (LLMs) is promising and LLMs have been applied to numerous fields. However, it is not trivial to implement LLMs in the medical field, due to the high standards for precision and accuracy. Currently, the…

Information Retrieval · Computer Science 2024-12-04 Rishabh Goel