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Deep neural networks are increasingly being used for the analysis of medical images. However, most works neglect the uncertainty in the model's prediction. We propose an uncertainty-aware deep kernel learning model which permits the…

Machine Learning · Computer Science 2021-06-11 Zhiliang Wu , Yinchong Yang , Jindong Gu , Volker Tresp

Tomographic imaging is in general an ill-posed inverse problem. Typically, a single regularized image estimate of the sought-after object is obtained from tomographic measurements. However, there may be multiple objects that are all…

Image and Video Processing · Electrical Eng. & Systems 2022-07-28 Sayantan Bhadra , Umberto Villa , Mark A. Anastasio

One of the most challenges in medical imaging is the lack of data and annotated data. It is proven that classical segmentation methods such as U-NET are useful but still limited due to the lack of annotated data. Using a weakly supervised…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Amine Amyar , Romain Modzelewski , Pierre Vera , Vincent Morard , Su Ruan

Imaging problems such as the one in nanoCT require the solution of an inverse problem, where it is often taken for granted that the forward operator, i.e., the underlying physical model, is properly known. In the present work we address the…

Recent deep learning approaches focus on improving quantitative scores of dedicated benchmarks, and therefore only reduce the observation-related (aleatoric) uncertainty. However, the model-immanent (epistemic) uncertainty is less…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Dominik Narnhofer , Alexander Effland , Erich Kobler , Kerstin Hammernik , Florian Knoll , Thomas Pock

A unified self-supervised and supervised deep learning framework for PET image reconstruction is presented, including deep-learned filtered backprojection (DL-FBP) for sinograms, deep-learned backproject then filter (DL-BPF) for…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Andrew J. Reader

We propose in this work a framework for synergistic positron emission tomography (PET)/computed tomography (CT) reconstruction using a joint generative model as a penalty. We use a synergistic penalty function that promotes PET/CT pairs…

Differentiable rendering has been widely adopted in computer graphics as a powerful approach to inverse problems, enabling efficient gradient-based optimization by differentiating the image formation process with respect to millions of…

Positron emission tomography (PET) is a widely recognized technique for diagnosing neurodegenerative diseases, offering critical functional insights. However, its high costs and radiation exposure hinder its widespread use. In contrast,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yitong Li , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

Positron emission tomography (PET) is widely used for clinical diagnosis. As PET suffers from low resolution and high noise, numerous efforts try to incorporate anatomical priors into PET image reconstruction, especially with the…

Medical Physics · Physics 2019-12-17 Nuobei Xie , Kuang Gong , Ning Guo , Zhixin Qin , Zhifang Wu , Huafeng Liu , Quanzheng Li

Parameter estimation and inference from complex survey samples typically focuses on global model parameters whose estimators have asymptotic properties, such as from fixed effects regression models. The central challenge is to both mitigate…

Methodology · Statistics 2026-05-13 Matthew R. Williams , F. Hunter McGuire , Terrance D. Savitsky

The data consistency for the physical forward model is crucial in inverse problems, especially in MR imaging reconstruction. The standard way is to unroll an iterative algorithm into a neural network with a forward model embedded. The…

Image and Video Processing · Electrical Eng. & Systems 2023-06-28 Guanxiong Luo , Mengmeng Kuang , Peng Cao

As a powerful technique in medical imaging, image synthesis is widely used in applications such as denoising, super resolution and modality transformation etc. Recently, the revival of deep neural networks made immense progress in the field…

Image and Video Processing · Electrical Eng. & Systems 2021-04-23 Gengyan Zhao , Mary E. Meyerand , Rasmus M. Birn

Ultrasound reflection tomography is widely used to image large complex specimens that are only accessible from a single side, such as well systems and nuclear power plant containment walls. Typical methods for inverting the measurement rely…

Image and Video Processing · Electrical Eng. & Systems 2018-10-01 Hani Almansouri , S. V. Venkatakrishnan , Gregery T. Buzzard , Charles A. Bouman , Hector Santos-Villalobos

Recent advances in deep pose estimation models have proven to be effective in a wide range of applications such as health monitoring, sports, animations, and robotics. However, pose estimation models fail to generalize when facing images…

Computer Vision and Pattern Recognition · Computer Science 2021-05-20 Vandad Davoodnia , Saeed Ghorbani , Ali Etemad

Existing deep-learning based tomographic image reconstruction methods do not provide accurate estimates of reconstruction uncertainty, hindering their real-world deployment. This paper develops a method, termed as the linearised deep image…

Image and Video Processing · Electrical Eng. & Systems 2022-11-07 Javier Antorán , Riccardo Barbano , Johannes Leuschner , José Miguel Hernández-Lobato , Bangti Jin

Effective quantification of uncertainty is an essential and still missing step towards a greater adoption of deep-learning approaches in different applications, including mission-critical ones. In particular, investigations on the…

Machine Learning · Computer Science 2023-04-14 Marco Forgione , Dario Piga

Low-resolution and signal-dependent noise distribution in positron emission tomography (PET) images makes denoising process an inevitable step prior to qualitative and quantitative image analysis tasks. Conventional PET denoising methods…

Computer Vision and Pattern Recognition · Computer Science 2014-07-14 Awais Mansoor , Ulas Bagci , Daniel J. Mollura

Positron emission tomography (PET) is a well-established functional imaging technique for diagnosing brain disorders. However, PET's high costs and radiation exposure limit its widespread use. In contrast, magnetic resonance imaging (MRI)…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Yitong Li , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

We present a new Bayesian methodology to learn the unknown material density of a given sample by inverting its two-dimensional images that are taken with a Scanning Electron Microscope. An image results from a sequence of projections of the…

Applications · Statistics 2014-03-06 Dalia Chakrabarty , Fabio Rigat , Nare Gabrielyan , Richard Beanland , Shashi Paul