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Score-based generative models (SGMs) have recently shown promising results for image reconstruction on simulated positron emission tomography (PET) datasets. In this work we have developed and implemented practical methodology for 3D image…

Positron emission tomography (PET) is a widely used, highly sensitive molecular imaging in clinical diagnosis. There is interest in reducing the radiation exposure from PET but also maintaining adequate image quality. Recent methods using…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Yuxin Xue , Lei Bi , Yige Peng , Michael Fulham , David Dagan Feng , Jinman Kim

Ptychography is a scanning coherent diffractive imaging technique that enables imaging nanometer-scale features in extended samples. One main challenge is that widely used iterative image reconstruction methods often require significant…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Canberk Ekmekci , Tekin Bicer , Zichao Wendy Di , Junjing Deng , Mujdat Cetin

Positron Emission Particle Tracking (PEPT) is an imaging method for the visualization of fluid motion, capable of reconstructing three-dimensional trajectories of small tracer particles suspended in nearly any medium, including fluids that…

Instrumentation and Detectors · Physics 2023-03-20 Avshalom Offner , Sam Manger , Jacques Vanneste

Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…

Images from positron emission tomography (PET) provide metabolic information about the human body. They present, however, a spatial resolution that is limited by physical and instrumental factors often modeled by a blurring function. Since…

Computer Vision and Pattern Recognition · Computer Science 2016-08-08 Stéphanie Guérit , Adriana González , Anne Bol , John A. Lee , Laurent Jacques

We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

This article presents a physics-informed deep learning method for the quantitative estimation of the spatial coordinates of gamma interactions within a monolithic scintillator, with a focus on Positron Emission Tomography (PET) imaging. A…

Convolutional neural network (CNN) has achieved unprecedented success in image super-resolution tasks in recent years. However, the network's performance depends on the distribution of the training sets and degrades on out-of-distribution…

Computer Vision and Pattern Recognition · Computer Science 2021-05-20 Aupendu Kar , Prabir Kumar Biswas

Uncertainty quantification is essential when dealing with ill-conditioned inverse problems due to the inherent nonuniqueness of the solution. Bayesian approaches allow us to determine how likely an estimation of the unknown parameters is…

Machine Learning · Statistics 2020-01-16 Ali Siahkoohi , Gabrio Rizzuti , Felix J. Herrmann

Positron Emission Tomography (PET) is an imaging technique which can be used to investigate chemical changes in human biological processes such as cancer development or neurochemical reactions. Most dynamic PET scans are currently analyzed…

Applications · Statistics 2014-11-11 Ci-Ren Jiang , John A D Aston , Jane-Ling Wang

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

Medical Physics · Physics 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang

Deep unrolling is an emerging deep learning-based image reconstruction methodology that bridges the gap between model-based and purely deep learning-based image reconstruction methods. Although deep unrolling methods achieve…

Image and Video Processing · Electrical Eng. & Systems 2022-12-21 Canberk Ekmekci , Mujdat Cetin

To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yuchen Fei , Yanmei Luo , Yan Wang , Jiaqi Cui , Yuanyuan Xu , Jiliu Zhou , Dinggang Shen

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

Positron Emission Tomography (PET) is a functional imaging modality widely used in neuroscience studies. To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. For PET/MR…

Medical Physics · Physics 2018-08-01 Kuang Gong , Jaewon Yang , Kyungsang Kim , Georges El Fakhri , Youngho Seo , Quanzheng Li

Low-count positron emission tomography (PET) reconstruction is a challenging inverse problem due to severe degradations arising from Poisson noise, photon scarcity, and attenuation correction errors. Existing deep learning methods typically…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Zheng Zhang , Hao Tang , Yingying Hu , Zhanli Hu , Jing Qin

Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Yucun Hou , Fenglin Zhan , Xin Cheng , Chenxi Li , Ziquan Yuan , Runze Liao , Haihao Wang , Jianlang Hua , Jing Wu , Jianyong Jiang

Aleatoric uncertainty is an intrinsic property of ill-posed inverse and imaging problems. Its quantification is vital for assessing the reliability of relevant point estimates. In this paper, we propose an efficient framework for…

Image and Video Processing · Electrical Eng. & Systems 2020-01-16 Chen Zhang , Bangti Jin

In this paper, we review physics- and data-driven reconstruction techniques for simultaneous positron emission tomography (PET) / magnetic resonance imaging (MRI) systems, which have significant advantages for clinical imaging of cancer,…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Abhejit Rajagopal , Andrew P. Leynes , Nicholas Dwork , Jessica E. Scholey , Thomas A. Hope , Peder E. Z. Larson