English
Related papers

Related papers: Large-Scale Cell Representation Learning via Divid…

200 papers

Large language models (LLMs) are trained on huge amounts of textual data, and concerns have been raised that the limits of such data may soon be reached. A potential solution is to train on synthetic data sampled from LLMs. In this work, we…

Computation and Language · Computer Science 2025-10-10 Jannek Ulm , Kevin Du , Vésteinn Snæbjarnarson

Learning good representations involves capturing the diverse ways in which data samples relate. Contrastive loss - an objective matching related samples - underlies methods from self-supervised to multimodal learning. Contrastive losses,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Vlad Sobal , Mark Ibrahim , Randall Balestriero , Vivien Cabannes , Diane Bouchacourt , Pietro Astolfi , Kyunghyun Cho , Yann LeCun

Currently, learning better unsupervised sentence representations is the pursuit of many natural language processing communities. Lots of approaches based on pre-trained language models (PLMs) and contrastive learning have achieved promising…

Computation and Language · Computer Science 2023-05-11 Nuo Chen , Linjun Shou , Ming Gong , Jian Pei , Bowen Cao , Jianhui Chang , Daxin Jiang , Jia Li

Recent multimodal models such as Contrastive Language-Image Pre-training (CLIP) have shown remarkable ability to align visual and linguistic representations. However, domains where small visual differences carry large semantic significance,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hiroshi Sasaki

A new trend uses LLMs as dense text encoders via contrastive learning. However, since LLM embeddings predict the probability distribution of the next token, they are inherently generative and distributive, conflicting with contrastive…

Computation and Language · Computer Science 2025-10-17 Jingcheng Deng , Zhongtao Jiang , Liang Pang , Liwei Chen , Kun Xu , Zihao Wei , Huawei Shen , Xueqi Cheng

Disease diagnosis from medical images via supervised learning is usually dependent on tedious, error-prone, and costly image labeling by medical experts. Alternatively, semi-supervised learning and self-supervised learning offer…

Computer Vision and Pattern Recognition · Computer Science 2023-06-14 Attiano Purpura-Pontoniere , Demetri Terzopoulos , Adam Wang , Abdullah-Al-Zubaer Imran

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

Deep learning has demonstrated expert-level performance in melanoma classification, positioning it as a powerful tool in clinical dermatology. However, model opacity and the lack of interpretability remain critical barriers to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Junwen Zheng , Xinran Xu , Li Rong Wang , Chang Cai , Lucinda Siyun Tan , Dingyuan Wang , Hong Liang Tey , Xiuyi Fan

Objective: Biomedical Knowledge Graphs play a pivotal role in various biomedical research domains. Concurrently, term clustering emerges as a crucial step in constructing these knowledge graphs, aiming to identify synonymous terms. Due to a…

Computation and Language · Computer Science 2023-12-14 Huaiyuan Ying , Zhengyun Zhao , Yang Zhao , Sihang Zeng , Sheng Yu

The use of episodic memory in continual learning has demonstrated effectiveness for alleviating catastrophic forgetting. In recent studies, gradient-based approaches have been developed to make more efficient use of compact episodic memory.…

Machine Learning · Statistics 2022-04-15 Yu Chen , Tom Diethe , Peter Flach

This paper presents a novel training method, Conditional Masked Language Modeling (CMLM), to effectively learn sentence representations on large scale unlabeled corpora. CMLM integrates sentence representation learning into MLM training by…

Computation and Language · Computer Science 2021-09-13 Ziyi Yang , Yinfei Yang , Daniel Cer , Jax Law , Eric Darve

The rise of single-cell sequencing technologies has revolutionized the exploration of drug resistance, revealing the crucial role of cellular heterogeneity in advancing precision medicine. By building computational models from existing…

Genomics · Quantitative Biology 2025-02-05 Yu-An Huang , Xiyue Cao , Zhu-Hong You , Yue-Chao Li , Xuequn Shang , Zhi-An Huang

We present a unified vision-language framework tailored for ENT endoscopy image analysis that simultaneously tackles three clinically-relevant tasks: image classification, image-to-image retrieval, and text-to-image retrieval. Unlike…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Y Hop Nguyen , Doan Anh Phan Huu , Trung Thai Tran , Nhat Nam Mai , Van Toi Giap , Thao Thi Phuong Dao , Trung-Nghia Le

Large language models (LLMs) have demonstrated their remarkable performance across various language understanding tasks. While emerging benchmarks have been proposed to evaluate LLMs in various domains such as mathematics and computer…

Artificial Intelligence · Computer Science 2024-10-28 Junnan Dong , Zijin Hong , Yuanchen Bei , Feiran Huang , Xinrun Wang , Xiao Huang

Sign Language Translation (SLT) is a promising technology to bridge the communication gap between the deaf and the hearing people. Recently, researchers have adopted Neural Machine Translation (NMT) methods, which usually require…

Computation and Language · Computer Science 2023-03-22 Biao Fu , Peigen Ye , Liang Zhang , Pei Yu , Cong Hu , Yidong Chen , Xiaodong Shi

Multimodal large language models (MLLMs) have experienced significant advancements recently, but still struggle to recognize and interpret intricate details in high-resolution (HR) images effectively. While state-of-the-art (SOTA) MLLMs…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Wenbin Wang , Liang Ding , Minyan Zeng , Xiabin Zhou , Li Shen , Yong Luo , Dacheng Tao

High-throughput RNA-sequencing (RNA-seq) technologies are powerful tools for understanding cellular state. Often it is of interest to quantify and summarize changes in cell state that occur between experimental or biological conditions.…

Methodology · Statistics 2021-02-16 Andrew Jones , F. William Townes , Didong Li , Barbara E. Engelhardt

Single-cell RNA-sequencing (scRNA-seq) has become a routinely used technique to quantify the gene expression profile of thousands of single cells simultaneously. Analysis of scRNA-seq data plays an important role in the study of cell states…

Genomics · Quantitative Biology 2022-10-13 Matthew Brendel , Chang Su , Zilong Bai , Hao Zhang , Olivier Elemento , Fei Wang

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

Computation and Language · Computer Science 2025-03-07 Jiyue Jiang , Zikang Wang , Yuheng Shan , Heyan Chai , Jiayi Li , Zixian Ma , Xinrui Zhang , Yu Li

Large-scale cross-lingual pre-trained language models (xPLMs) have shown effectiveness in cross-lingual sequence labeling tasks (xSL), such as cross-lingual machine reading comprehension (xMRC) by transferring knowledge from a high-resource…

Computation and Language · Computer Science 2022-04-12 Nuo Chen , Linjun Shou , Ming Gong , Jian Pei , Daxin Jiang