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Existing biomedical benchmarks do not provide end-to-end infrastructure for training, evaluation, and inference of models that integrate multimodal biological data and a broad range of machine learning tasks in therapeutics. We present…

Machine Learning · Computer Science 2026-01-23 Alejandro Velez-Arce , Jesus Caraballo , Marinka Zitnik

Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

Computation and Language · Computer Science 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

While interest in the application of machine learning to improve healthcare has grown tremendously in recent years, a number of barriers prevent deployment in medical practice. A notable concern is the potential to exacerbate entrenched…

Machine Learning · Computer Science 2022-05-19 Isabel Chien , Nina Deliu , Richard E. Turner , Adrian Weller , Sofia S. Villar , Niki Kilbertus

Nowadays, intelligent systems and services are getting increasingly popular as they provide data-driven solutions to diverse real-world problems, thanks to recent breakthroughs in Artificial Intelligence (AI) and Machine Learning (ML).…

Software Engineering · Computer Science 2022-01-03 Md Saidur Rahman , Foutse Khomh , Alaleh Hamidi , Jinghui Cheng , Giuliano Antoniol , Hironori Washizaki

Reproducibility is a crucial requirement in scientific research. When results of research studies and scientific papers have been found difficult or impossible to reproduce, we face a challenge which is called reproducibility crisis.…

Software Engineering · Computer Science 2021-09-10 Emilio Rivera-Landos , Foutse Khomh , Amin Nikanjam

The integration of artificial intelligence [AI] into clinical trials has revolutionized the process of drug development and personalized medicine. Among these advancements, deep learning and predictive modelling have emerged as…

Machine Learning · Computer Science 2024-12-11 Sydney Anuyah , Mallika K Singh , Hope Nyavor

Clinical trials need to recruit a sufficient number of volunteer patients to demonstrate the statistical power of the treatment (e.g., a new drug) in curing a certain disease. Clinical trial recruitment has a significant impact on trial…

Machine Learning · Computer Science 2024-07-19 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

This report embarks on a mission to revolutionize clinical trial protocol development through the integration of advanced AI technologies. With a focus on leveraging the capabilities of generative AI, specifically GPT-4, this initiative…

Computational Engineering, Finance, and Science · Computer Science 2024-08-06 Morteza Maleki , SeyedAli Ghahari

Causal machine learning (ML) offers flexible, data-driven methods for predicting treatment outcomes including efficacy and toxicity, thereby supporting the assessment and safety of drugs. A key benefit of causal ML is that it allows for…

Nowadays, we are witnessing a wide adoption of Machine learning (ML) models in many safety-critical systems, thanks to recent breakthroughs in deep learning and reinforcement learning. Many people are now interacting with systems based on…

Software Engineering · Computer Science 2018-12-07 Houssem Ben Braiek , Foutse Khomh

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

We aim to conduct a systematic mapping in the area of testing ML programs. We identify, analyze and classify the existing literature to provide an overview of the area. We followed well-established guidelines of systematic mapping to…

Machine Learning · Computer Science 2019-07-23 Salman Sherin , Muhammad Uzair khan , Muhammad Zohaib Iqbal

The use of machine learning in Healthcare has the potential to improve patient outcomes as well as broaden the reach and affordability of Healthcare. The history of other application areas indicates that strong benchmarks are essential for…

Scientific publications about machine learning in healthcare are often about implementing novel methods and boosting the performance - at least from a computer science perspective. However, beyond such often short-lived improvements, much…

With the advent of sophisticated machine learning (ML) techniques and the promising results they yield, especially in medical applications, where they have been investigated for different tasks to enhance the decision-making process. Since…

The sheer number of research outputs published every year makes systematic reviewing increasingly time- and resource-intensive. This paper explores the use of machine learning techniques to help navigate the systematic review process. ML…

Machine Learning (ML) has recently shown tremendous success in modeling various healthcare prediction tasks, ranging from disease diagnosis and prognosis to patient treatment. Due to the sensitive nature of medical data, privacy must be…

Machine Learning · Computer Science 2024-10-01 Alejandro Guerra-Manzanares , L. Julian Lechuga Lopez , Michail Maniatakos , Farah E. Shamout

Research on decision support applications in healthcare, such as those related to diagnosis, prediction, treatment planning, etc., have seen enormously increased interest recently. This development is thanks to the increase in data…

Machine Learning · Computer Science 2021-03-25 Jussi Tohka , Mark van Gils

Recent advances in Artificial Intelligence (AI), especially in Machine Learning (ML), have introduced various practical applications (e.g., virtual personal assistants and autonomous cars) that enhance the experience of everyday users.…

Software Engineering · Computer Science 2020-12-09 Minke Xiu , Ellis E. Eghan , Zhen Ming , Jiang , Bram Adams

Clinical trials are pivotal in the drug discovery process to determine the safety and efficacy of a drug candidate. The high failure rates of these trials are attributed to deficiencies in clinical model development and protocol design.…