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In this paper, we combined linguistic complexity and (dis)fluency features with pretrained language models for the task of Alzheimer's disease detection of the 2021 ADReSSo (Alzheimer's Dementia Recognition through Spontaneous Speech)…

Computation and Language · Computer Science 2021-06-17 Yu Qiao , Xuefeng Yin , Daniel Wiechmann , Elma Kerz

Visualizing and interpreting convolutional neural networks (CNNs) is an important task to increase trust in automatic medical decision making systems. In this study, we train a 3D CNN to detect Alzheimer's disease based on structural MRI…

Computer Vision and Pattern Recognition · Computer Science 2018-12-07 Johannes Rieke , Fabian Eitel , Martin Weygandt , John-Dylan Haynes , Kerstin Ritter

Deep learning is attracting significant interest in the neuroimaging community as a means to diagnose psychiatric and neurological disorders from structural magnetic resonance images. However, there is a tendency amongst researchers to…

Machine Learning · Computer Science 2019-10-22 David Wood , James Cole , Thomas Booth

Alzheimer's disease is the most common cause of dementia, yet difficult to accurately diagnose without the use of invasive techniques, particularly at the beginning of the disease. This work addresses the classification and analysis of…

Computer Vision and Pattern Recognition · Computer Science 2017-12-06 Wellington Pinheiro dos Santos , Ricardo Emmanuel de Souza , Ascendino Flávio Dias e Silva , Plínio Batista dos Santos Filho

Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression…

Machine Learning · Computer Science 2018-12-07 Vipul Satone , Rachneet Kaur , Faraz Faghri , Mike A Nalls , Andrew B Singleton , Roy H Campbell

Alzheimers Disease AD is an acute neuro disease that degenerates the brain cells and thus leads to memory loss progressively. It is a fatal brain disease that mostly affects the elderly. It steers the decline of cognitive and biological…

Machine Learning · Computer Science 2023-04-20 Nair Bini Balakrishnan , P. S. Sreeja , Jisha Jose Panackal

Although Alzheimer's disease detection via MRIs has advanced significantly thanks to contemporary deep learning models, challenges such as class imbalance, protocol variations, and limited dataset diversity often hinder their generalization…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Zobia Batool , Huseyin Ozkan , Erchan Aptoula

Alzheimers disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimers disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8 to 4.4 years after…

Alzheimer's is a brain disease that gets worse over time and affects memory, thinking, and behavior. Alzheimer's disease (AD) can be treated and managed if it is diagnosed early, which can slow the progression of symptoms and improve…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Taymaz Akan , Sait Alp , Mohammad A. N Bhuiyanb

With the ongoing development of deep learning, an increasing number of AI models have surpassed the performance levels of human clinical practitioners. However, the prevalence of AI diagnostic products in actual clinical practice remains…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Chenglong Wang , Yinqiao Yi , Yida Wang , Chengxiu Zhang , Yun Liu , Kensaku Mori , Mei Yuan , Guang Yang

This paper explores interpretability techniques for two of the most successful learning algorithms in medical decision-making literature: deep neural networks and random forests. We applied these algorithms in a real-world medical dataset…

Machine Learning · Computer Science 2020-02-24 Catarina Moreira , Renuka Sindhgatta , Chun Ouyang , Peter Bruza , Andreas Wichert

Deep Neural Networks (DNNs) have an enormous potential to learn from complex biomedical data. In particular, DNNs have been used to seamlessly fuse heterogeneous information from neuroanatomy, genetics, biomarkers, and neuropsychological…

Machine Learning · Computer Science 2021-10-04 Sebastian Pölsterl , Christina Aigner , Christian Wachinger

Accurately discriminating progressive stages of Alzheimer's Disease (AD) is crucial for early diagnosis and prevention. It often involves multiple imaging modalities to understand the complex pathology of AD, however, acquiring a complete…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Seunghun Baek , Jaeyoon Sim , Guorong Wu , Won Hwa Kim

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

In the last decade, computer-aided early diagnostics of Alzheimer's Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research. Some recent studies have shown promising results in the AD…

Computer Vision and Pattern Recognition · Computer Science 2018-09-12 Alexander Khvostikov , Karim Aderghal , Andrey Krylov , Gwenaelle Catheline , Jenny Benois-Pineau

The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…

Alzheimer's Disease is the most common cause of dementia. Accurate diagnosis and prognosis of this disease are essential to design an appropriate treatment plan, increasing the life expectancy of the patient. Intense research has been…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Developing successful artificial intelligence systems in practice depends on both robust deep learning models and large, high-quality data. However, acquiring and labeling data can be prohibitively expensive and time-consuming in many…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Saba Dadsetan , Mohsen Hejrati , Shandong Wu , Somaye Hashemifar

Early and accurate detection of Alzheimer's disease (AD) remains a major challenge in medical diagnosis due to its subtle onset and progressive nature. This research introduces an explainable ensemble learning Framework designed to classify…

Machine Learning · Computer Science 2026-03-06 Nishan Mitra
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