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Source analysis of Electroencephalography (EEG) data requires the computation of the scalp potential induced by current sources in the brain. This so-called EEG forward problem is based on an accurate estimation of the volume conduction…

We propose a boundary element method for the accurate solution of the cell-by-cell bidomain model of electrophysiology. The cell-by-cell model, also called Extracellular-Membrane-Intracellular (EMI) model, is a system of reaction-diffusion…

Numerical Analysis · Mathematics 2024-06-28 Giacomo Rosilho de Souza , Rolf Krause , Simone Pezzuto

The Extracellular-Membrane-Intracellular (EMI) model is a novel mathematical framework for cardiac electrophysiology simulations. The EMI model provides a more detailed description of the heart's electrical activity compared to traditional…

Numerical Analysis · Mathematics 2025-04-29 Carlos Ballesteros , Alexei Cheviakov , Raymond J. Spiteri

The finite element method (FEM) is a well-established numerical method for solving partial differential equations (PDEs). However, its mesh-based nature gives rise to substantial computational costs, especially for complex multiscale…

Computational Engineering, Finance, and Science · Computer Science 2025-06-24 Weihang Ouyang , Yeonjong Shin , Si-Wei Liu , Lu Lu

In this work, we are interested in solving large linear systems stemming from the Extra-Membrane-Intra (EMI) model, which is employed for simulating excitable tissues at a cellular scale. After setting the related systems of partial…

Numerical Analysis · Mathematics 2023-08-24 Pietro Benedusi , Paola Ferrari , Marie Rognes , Stefano Serra-Capizzano

In the present study, we consider the Extra-Membrane-Intra model (EMI) for the simulation of excitable tissues at the cellular level. We provide the (possibly large) system of partial differential equations (PDEs), equipped with ad hoc…

Numerical Analysis · Mathematics 2024-09-23 Pietro Benedusi , Paola Ferrari , Marius Causemann , Stefano Serra-Capizzano

In this work, we investigate the performance CutFEM as a high fidelity solver as well as we construct a competent and economical reduced order solver for PDE-constrained optimization problems in parametrized domains that live in a fixed…

Numerical Analysis · Mathematics 2022-04-11 Georgios Katsouleas , Efthymios N. Karatzas , Fotios Travlopanos

Mathematical models for excitable cells are commonly based on cable theory, which considers a homogenized domain and spatially constant ionic concentrations. Although such models provide valuable insight, the effect of altered ion…

Computational Engineering, Finance, and Science · Computer Science 2019-11-11 A. J. Ellingsrud , A. Solbrå , G. T. Einevoll , G. Halnes , M. E. Rognes

We present a method of CutFEM type for the Poisson problem with either Dirichlet or Neumann boundary conditions. The computational mesh is obtained from a background (typically uniform Cartesian) mesh by retaining only the elements…

Numerical Analysis · Mathematics 2019-09-04 Alexei Lozinski

We develop a cut finite element method (CutFEM) for convection-diffusion problems posed on mixed-dimensional domains, i.e., unions of manifolds of different dimensions arranged in a hierarchical structure where lower-dimensional components…

Numerical Analysis · Mathematics 2026-04-09 Erik Burman , Peter Hansbo , Mats G. Larson , Karl Larsson , Shantiram Mahata

Unfitted finite element methods, like CutFEM, have traditionally been implemented in a matrix-based fashion, where a sparse matrix is assembled and later applied to vectors while solving the resulting linear system. With the goal of…

Numerical Analysis · Mathematics 2024-04-15 Maximilian Bergbauer , Peter Munch , Wolfgang A. Wall , Martin Kronbichler

We present a methodology combining neural networks with physical principle constraints in the form of partial differential equations (PDEs). The approach allows to train neural networks while respecting the PDEs as a strong constraint in…

Numerical Analysis · Mathematics 2021-09-06 Sebastian K. Mitusch , Simon W. Funke , Miroslav Kuchta

Computational modelling offers a cost-effective and time-efficient alternative to experimental studies in biomedical engineering. In cardiac electro-mechanics, finite element method (FEM)-based simulations provide valuable insights into…

Computational Engineering, Finance, and Science · Computer Science 2025-08-20 Tan Tran , Denisa Martonova , Sigrid Leyendecker

This paper describes the use of the corotational cut Finite Element Method (FEM) for real-time surgical simulation. Users only need to provide a background mesh which is not necessarily conforming to the boundaries/interfaces of the…

Computational Engineering, Finance, and Science · Computer Science 2018-11-20 Huu Phuoc Bui , Satyendra Tomar , Stéphane P. A. Bordas

In this paper we consider a class of unfitted finite element methods for scalar elliptic problems. These so-called CutFEM methods use standard finite element spaces on a fixed unfitted triangulation combined with the Nitsche technique and a…

Numerical Analysis · Mathematics 2022-12-26 Sven Gross , Arnold Reusken

A novel multi-scale finite element formulation for contact mechanics between nominally smooth but microscopically rough surfaces is herein proposed. The approach integrates the interface finite element method (FEM) for modelling interface…

Computational Engineering, Finance, and Science · Computer Science 2025-04-03 Jacopo Bonari , Maria R. Marulli , Nora Hagmeyer , Matthias Mayr , Alexander Popp , Marco Paggi

This paper introduces an accurate edge-based smoothed finite element method (ES-FEM) for electromagnetic analysis for both two dimensional cylindrical and three dimensional cartesian systems, which shows much better performance in terms of…

Computational Engineering, Finance, and Science · Computer Science 2019-10-30 Yangfan Zhang , Pengfei Wang , Wenping Li , Shunchuan Yang

One of the major issues in the computational mechanics is to take into account the geometrical complexity. To overcome this difficulty and to avoid the expensive mesh generation, geometrically unfitted methods, i.e. the numerical methods…

Numerical Analysis · Mathematics 2021-10-12 Stephane Cotin , Michel Duprez , Vanessa Lleras , Alexei Lozinski , Killian Vuillemot

A surface integral representation of Maxwell's equations allows the efficient electromagnetic (EM) modeling of three-dimensional structures with a two-dimensional discretization, via the boundary element method (BEM). However, existing BEM…

Numerical Analysis · Mathematics 2021-12-14 Shashwat Sharma , Piero Triverio

When modeling scientific and industrial problems, geometries are typically modeled by explicit boundary representations obtained from computer-aided design software. Unfitted (also known as embedded or immersed) finite element methods offer…

Computational Engineering, Finance, and Science · Computer Science 2024-05-24 Pere A. Martorell , Santiago Badia
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