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A branching process in varying environment with generation-dependent immigration is a modification of the standard branching process in which immigration is allowed and the reproduction and immigration laws may vary over the generations.…

Probability · Mathematics 2024-01-31 Miguel González , Goetz Kersting , Carmen Minuesa , Inés del Puerto

Bacteriophages spreading through populations of bacteria offer relatively simple, tuneable systems for testing mathematical models of range expansion. However, such models typically assume a static state into which to expand, which is not…

Soft Condensed Matter · Physics 2024-04-02 Rory Claydon , Samuel Gartenstein , Aidan T. Brown

To maintain a constant cell size, dividing cells have to coordinate cell cycle events with cell growth. This coordination has for long been supposed to rely on the existence of size thresholds determining cell cycle progression [1]. In…

Cell Behavior · Quantitative Biology 2016-11-04 Ilya Soifer , Lydia Robert , Ariel Amir

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

Biological Physics · Physics 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

We extend our BDI (birth-death-immigration) process based stochastic model of an infectious disease to time-nonhomogeneous cases. First, we discuss the deterministic model, and derive the expected value of the infection process. Then as an…

Methodology · Statistics 2021-01-25 Hisashi Kobayashi

Budding allows virus replication and macromolecular secretion in cells. It involves the formation of a bud, i.e. an outgrowth from the cell membrane that evolves into an envelope. The largest energetic barrier to bud formation is membrane…

Biological Physics · Physics 2022-10-17 Mattia Bacca

Two powerful and complementary experimental approaches are commonly used to study the cell cycle and cell biology: One class of experiments characterizes the statistics (or demographics) of an unsynchronized exponentially-growing…

Biological Physics · Physics 2022-02-02 Dean Huang , Teresa Lo , Houra Merrikh , Paul A. Wiggins

We present a stochastic model for two successive SIR (Susceptible, Infectious, Recovered) epidemics in the same network structured population. Individuals infected during the first epidemic might have (partial) immunity for the second one.…

Populations and Evolution · Quantitative Biology 2024-10-29 Frank Ball , Abid Ali Lashari , David Sirl , Pieter Trapman

Continuous-time birth-death-shift (BDS) processes are frequently used in stochastic modeling, with many applications in ecology and epidemiology. In particular, such processes can model evolutionary dynamics of transposable elements -…

Methodology · Statistics 2014-12-02 Jason Xu , Peter Guttorp , Midori Kato-Maeda , Vladimir N. Minin

Between pandemics, the influenza virus exhibits periods of incremental evolution via a process known as antigenic drift. This process gives rise to a sequence of strains of the pathogen that are continuously replaced by newer strains,…

Populations and Evolution · Quantitative Biology 2020-08-18 Adam Griffin , Simon E. F. Spencer , Gareth O. Roberts

The segregation of plasmids in a bacterial population is investigated. Hereby, a dynamical model is formulated in terms of a size-structured population using a hyperbolic partial differential equation incorporating non-local terms (the…

Populations and Evolution · Quantitative Biology 2017-01-13 Johannes Müller , Karin Münch , Bendix Koopmann , Eva Stadler , Louisa Roselius , Dieter Jahn , Richard Münch

We consider a binary branching process structured by a stochastic trait that evolves according to a diffusion process that triggers the branching events, in the spirit of Kimmel's model of cell division with parasite infection. Based on the…

Statistics Theory · Mathematics 2019-02-27 Marc Hoffmann , Aline Marguet

Maintenance and regeneration of adult tissues rely on the self-renewal of stem cells. Regeneration without over-proliferation requires precise regulation of the stem cell proliferation and differentiation rates. The nature of such…

Populations and Evolution · Quantitative Biology 2022-12-19 Rodrigo García-Tejera , Linus Schumacher , Ramon Grima

We consider a branching particle system where each particle moves as an independent Brownian motion and breeds at a rate proportional to its distance from the origin raised to the power $p$, for $p\in[0,2)$. The asymptotic behaviour of the…

Probability · Mathematics 2014-02-24 Julien Berestycki , Éric Brunet , John W. Harris , Simon C. Harris , Matthew I. Roberts

We study the spread of stochastic SIR (Susceptible $\to$ Infectious $\to$ Recovered) epidemics in two types of structured populations, both consisting of schools and households. In each of the types, every individual is part of one school…

Physics and Society · Physics 2015-03-23 Tanneke Ouboter , Ronald Meester , Pieter Trapman

The growth of a population is often modeled as branching process where each individual at the end of its life is replaced by a certain number of offspring. An example of these branching models is the Bellman-Harris process, where the…

We study an epidemic model for a constant population by taking into account four compartments of the individuals characterizing their states of health. Each individual is in one of the compartments susceptible (S); incubated - infected yet…

Populations and Evolution · Quantitative Biology 2023-04-20 Teo Granger , Thomas M. Michelitsch , Michael Bestehorn , Alejandro P. Riascos , Bernard A. Collet

Branching processes are classical growth models in cell kinetics. In their construction, it is usually assumed that cell lifetimes are independent random variables, which has been proved false in experiments. Models of dependent lifetimes…

Populations and Evolution · Quantitative Biology 2013-07-02 Sana Louhichi , Bernard Ycart

We consider a branching-selection particle system on the real line. In this model the total size of the population at time $n$ is limited by $\exp\left(a n^{1/3}\right)$. At each step $n$, every individual dies while reproducing…

Probability · Mathematics 2018-10-02 Bastien Mallein

We study the growth of a population of bacteria in a dynamical hostile environment corresponding to the immune system of the colonised organism. The immune cells evolve as subcritical open clusters of oriented percolation and are…

Populations and Evolution · Quantitative Biology 2013-10-07 Olivier Garet , Régine Marchand