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Clinical trials need to recruit a sufficient number of volunteer patients to demonstrate the statistical power of the treatment (e.g., a new drug) in curing a certain disease. Clinical trial recruitment has a significant impact on trial…

Machine Learning · Computer Science 2024-07-19 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

Clinical trial eligibility matching is a critical yet often labor-intensive and error-prone step in medical research, as it ensures that participants meet precise criteria for safe and reliable study outcomes. Recent advances in Natural…

Machine Learning · Computer Science 2025-03-04 Muhammad Talha Sharif , Abdul Rehman

There is a long history of building predictive models in healthcare using tabular data from electronic medical records. However, these models fail to extract the information found in unstructured clinical notes, which document diagnosis,…

Computation and Language · Computer Science 2025-04-18 David Anderson , Michaela Anderson , Margret Bjarnadottir , Stephen Mahar , Shriyan Reyya

Widespread adoption of electronic health records (EHRs) has fueled the development of using machine learning to build prediction models for various clinical outcomes. This process is often constrained by having a relatively small number of…

Computation and Language · Computer Science 2020-05-14 Ethan Steinberg , Ken Jung , Jason A. Fries , Conor K. Corbin , Stephen R. Pfohl , Nigam H. Shah

Significant advancements have been made in recent years to optimize patient recruitment for clinical trials, however, improved methods for patient recruitment prediction are needed to support trial site selection and to estimate appropriate…

Machine Learning · Computer Science 2021-11-16 Jingshu Liu , Patricia J Allen , Luke Benz , Daniel Blickstein , Evon Okidi , Xiao Shi

Clinical trials are critical for drug development. Constructing the appropriate eligibility criteria (i.e., the inclusion/exclusion criteria for patient recruitment) is essential for the trial's success. Proper design of clinical trial…

Computation and Language · Computer Science 2023-10-10 Zifeng Wang , Cao Xiao , Jimeng Sun

Understanding deep learning model behavior is critical to accepting machine learning-based decision support systems in the medical community. Previous research has shown that jointly using clinical notes with electronic health record (EHR)…

Machine Learning · Computer Science 2022-12-07 Severin Husmann , Hugo Yèche , Gunnar Rätsch , Rita Kuznetsova

The continuously increasing cost of the US healthcare system has received significant attention. Central to the ideas aimed at curbing this trend is the use of technology, in the form of the mandate to implement electronic health records…

Information Retrieval · Computer Science 2017-03-24 Pranjul Yadav , Michael Steinbach , Vipin Kumar , Gyorgy Simon

With the advent of large language models (LLMs), there has been growing interest in exploring their potential for medical applications. This research aims to investigate the ability of LLMs, specifically ChatGPT, in the context of…

Computation and Language · Computer Science 2024-02-27 Zhaoyue Sun , Gabriele Pergola , Byron C. Wallace , Yulan He

Objectives: Electronic health records (EHRs) are only a first step in capturing and utilizing health-related data - the challenge is turning that data into useful information. Furthermore, EHRs are increasingly likely to include data…

Artificial Intelligence · Computer Science 2012-08-20 Casey Bennett , Tom Doub , Rebecca Selove

The successes of foundation models such as ChatGPT and AlphaFold have spurred significant interest in building similar models for electronic medical records (EMRs) to improve patient care and hospital operations. However, recent hype has…

Electronic health records (EHR) contain extensive structured and unstructured data, including tabular information and free-text clinical notes. Querying relevant patient information often requires complex database operations, increasing the…

Information Retrieval · Computer Science 2025-11-27 Mengliang ZHang

Synthetic Electronic Health Records (EHR) have emerged as a pivotal tool in advancing healthcare applications and machine learning models, particularly for researchers without direct access to healthcare data. Although existing methods,…

Electronic health records (EHR's) are only a first step in capturing and utilizing health-related data - the problem is turning that data into useful information. Models produced via data mining and predictive analysis profile inherited…

Databases · Computer Science 2011-12-08 Casey Bennett , Thomas Doub

ChatGPT, the most accessible generative artificial intelligence (AI) tool, offers considerable potential for veterinary medicine, yet a dedicated review of its specific applications is lacking. This review concisely synthesizes the latest…

Computers and Society · Computer Science 2024-05-24 Candice P. Chu

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

Recent advances in Large Language Models (LLMs) have led to remarkable progresses in medical consultation. However, existing medical LLMs overlook the essential role of Electronic Health Records (EHR) and focus primarily on diagnosis…

Artificial Intelligence · Computer Science 2025-06-26 Weijieying Ren , Tianxiang Zhao , Lei Wang , Tianchun Wang , Vasant Honavar

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Clinical trials (CTs) often fail due to inadequate patient recruitment. This paper tackles the challenges of CT retrieval by presenting an approach that addresses the patient-to-trials paradigm. Our approach involves two key components in a…

Information Retrieval · Computer Science 2023-07-04 Wojciech Kusa , Óscar E. Mendoza , Petr Knoth , Gabriella Pasi , Allan Hanbury

Information in electronic health records (EHR), such as clinical narratives, examination reports, lab measurements, demographics, and other patient encounter entries, can be transformed into appropriate data representations that can be used…

Machine Learning · Computer Science 2019-09-23 Wei-Hung Weng , Peter Szolovits