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We provide an overview of the diffusion model as a method to generate new samples. Generative models have been recently adopted for tasks such as art generation (Stable Diffusion, Dall-E) and text generation (ChatGPT). Diffusion models in…

Machine Learning · Statistics 2025-06-13 Justin Le

Processing temporal sequences is central to a variety of applications in health care, and in particular multi-channel Electrocardiogram (ECG) is a highly prevalent diagnostic modality that relies on robust sequence modeling. While Recurrent…

Machine Learning · Statistics 2018-07-17 Deepta Rajan , Jayaraman J. Thiagarajan

Synthetic electrocardiogram generation serves medical AI applications requiring privacy-preserving data sharing and training dataset augmentation. Current diffusion-based methods achieve high generation quality but require hundreds of…

Signal Processing · Electrical Eng. & Systems 2025-09-16 Vitalii Bondar , Serhii Semenov , Vira Babenko , Dmytro Holovniak

The development of machine learning for cardiac care is severely hampered by privacy restrictions on sharing real patient electrocardiogram (ECG) data. Although generative AI offers a promising solution, the real-world use of existing…

Recent promises of generative deep learning lately brought interest to its potential uses in neural engineering. In this paper we firstly review recently emerging studies on generating artificial electroencephalography (EEG) signals with…

Signal Processing · Electrical Eng. & Systems 2021-02-17 Ozan Ozdenizci , Deniz Erdogmus

Modern wearable devices are embedded with a range of noninvasive biomarker sensors that hold promise for improving detection and treatment of disease. One such sensor is the single-lead electrocardiogram (ECG) which measures electrical…

Machine Learning · Statistics 2020-12-02 Jeffrey Chan , Andrew C. Miller , Emily B. Fox

Despite significant recent progress in the area of Brain-Computer Interface (BCI), there are numerous shortcomings associated with collecting Electroencephalography (EEG) signals in real-world environments. These include, but are not…

Quantitative Methods · Quantitative Biology 2019-10-14 Nik Khadijah Nik Aznan , Amir Atapour-Abarghouei , Stephen Bonner , Jason Connolly , Noura Al Moubayed , Toby Breckon

Modelling partial differential equations (PDEs) is of crucial importance in science and engineering, and it includes tasks ranging from forecasting to inverse problems, such as data assimilation. However, most previous numerical and machine…

In real-world clinical practice, electrocardiograms (ECGs) are often captured and shared as photographs. However, publicly available ECG data, and thus most related research, relies on digital signals. This has led to a disconnect in which…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Xiaoyu Wang , Ramesh Nadarajah , Zhiqiang Zhang , David Wong

Conditional image synthesis based on user-specified requirements is a key component in creating complex visual content. In recent years, diffusion-based generative modeling has become a highly effective way for conditional image synthesis,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Zheyuan Zhan , Defang Chen , Jian-Ping Mei , Zhenghe Zhao , Jiawei Chen , Chun Chen , Siwei Lyu , Can Wang

Graph generative models are essential across diverse scientific domains by capturing complex distributions over relational data. Among them, graph diffusion models achieve superior performance but face inefficient sampling and limited…

Machine Learning · Computer Science 2025-06-17 Yiming Qin , Manuel Madeira , Dorina Thanou , Pascal Frossard

Diffusion models are a class of probabilistic generative models that have been widely used as a prior for image processing tasks like text conditional generation and inpainting. We demonstrate that these models can be adapted to make…

Machine Learning · Computer Science 2023-06-14 Marc Finzi , Anudhyan Boral , Andrew Gordon Wilson , Fei Sha , Leonardo Zepeda-Núñez

Biomedical signal processing extract meaningful information from physiological signals like electrocardiograms (ECGs), electroencephalograms (EEGs), and electromyograms (EMGs) to diagnose, monitor, and treat medical conditions and diseases…

Signal Processing · Electrical Eng. & Systems 2025-08-13 Justin London

Echocardiography (echo), or cardiac ultrasound, is the most widely used imaging modality for cardiac form and function due to its relatively low cost, rapid acquisition time, and non-invasive nature. However, ultrasound acquisitions are…

Quantitative Methods · Quantitative Biology 2025-07-18 David Choi , Milos Vukadinovic , Bryan He , Christina Binder , Yuki Sahashi , David Ouyang

The generation of high-quality medical time series data is essential for advancing healthcare diagnostics and safeguarding patient privacy. Specifically, synthesizing realistic phonocardiogram (PCG) signals offers significant potential as a…

Machine Learning · Computer Science 2024-12-24 Ainaz Jamshidi , Muhammad Arif , Sabir Ali Kalhoro , Alexander Gelbukh

Acceleration of machine learning research in healthcare is challenged by lack of large annotated and balanced datasets. Furthermore, dealing with measurement inaccuracies and exploiting unsupervised data are considered to be central to…

Signal Processing · Electrical Eng. & Systems 2019-01-11 Deepta Rajan , David Beymer , Girish Narayan

To make medical datasets accessible without sharing sensitive patient information, we introduce a novel end-to-end approach for generative de-identification of dynamic medical imaging data. Until now, generative methods have faced…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Hadrien Reynaud , Qingjie Meng , Mischa Dombrowski , Arijit Ghosh , Thomas Day , Alberto Gomez , Paul Leeson , Bernhard Kainz

Electrocardiogram (ECG)-based models have achieved strong performance in diagnostic tasks, yet they remain limited in modeling how cardiac dynamics evolve under external interventions. In particular, existing approaches focus primarily on…

Artificial Intelligence · Computer Science 2026-05-19 Zhikang Chen , Yue Wang , Sen Cui , Yu Zhang , Changshui Zhang , Tianling Ren , Tingting Zhu

Cardiovascular disease remains a significant problem in modern society. Among non-invasive techniques, the electrocardiogram (ECG) is one of the most reliable methods for detecting abnormalities in cardiac activities. However, ECG…

Signal Processing · Electrical Eng. & Systems 2023-03-22 Huy Pham , Konstantin Egorov , Alexey Kazakov , Semen Budennyy

Personalized electrocardiogram (ECG) generation is to simulate a patient's ECG digital twins tailored to specific conditions. It has the potential to transform traditional healthcare into a more accurate individualized paradigm, while…

Machine Learning · Computer Science 2026-02-03 Yongfan Lai , Bo Liu , Xinyan Guan , Qinghao Zhao , Hongyan Li , Shenda Hong