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The construction of three-dimensional multi-modal tissue maps provides an opportunity to spur interdisciplinary innovations across temporal and spatial scales through information integration. While the preponderance of effort is allocated…

A major goal of lung cancer screening is to identify individuals with particular phenotypes that are associated with high risk of cancer. Identifying relevant phenotypes is complicated by the variation in body position and body composition.…

Automated volumetric segmentation of the pancreas on cross-sectional imaging is needed for diagnosis and follow-up of pancreatic diseases. While CT-based pancreatic segmentation is more established, MRI-based segmentation methods are…

Automatic organ segmentation is an important yet challenging problem for medical image analysis. The pancreas is an abdominal organ with very high anatomical variability. This inhibits previous segmentation methods from achieving high…

Computer Vision and Pattern Recognition · Computer Science 2015-06-23 Holger R. Roth , Le Lu , Amal Farag , Hoo-Chang Shin , Jiamin Liu , Evrim Turkbey , Ronald M. Summers

An accurate segmentation of the pancreas on CT is crucial to identify pancreatic pathologies and extract imaging-based biomarkers. However, prior research on pancreas segmentation has primarily focused on modifying the segmentation model…

Image and Video Processing · Electrical Eng. & Systems 2025-04-10 Anisa V. Prasad , Tejas Sudharshan Mathai , Pritam Mukherjee , Jianfei Liu , Ronald M. Summers

Pancreas segmentation has been traditionally challenging due to its small size in computed tomography abdominal volumes, high variability of shape and positions among patients, and blurred boundaries due to low contrast between the pancreas…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Andrea Moglia , Matteo Cavicchioli , Luca Mainardi , Pietro Cerveri

PanTS is a large-scale, multi-institutional dataset curated to advance research in pancreatic CT analysis. It contains 36,390 CT scans from 145 medical centers, with expert-validated, voxel-wise annotations of over 993,000 anatomical…

This paper proposes a fully automated atlas-based pancreas segmentation method from CT volumes utilizing atlas localization by regression forest and atlas generation using blood vessel information. Previous probabilistic atlas-based…

Computer Vision and Pattern Recognition · Computer Science 2020-05-08 Masahiro Oda , Natsuki Shimizu , Ken'ichi Karasawa , Yukitaka Nimura , Takayuki Kitasaka , Kazunari Misawa , Michitaka Fujiwara , Daniel Rueckert , Kensaku Mori

The pancreatic disease taxonomy includes ten types of masses (tumors or cysts)[20,8]. Previous work focuses on developing segmentation or classification methods only for certain mass types. Differential diagnosis of all mass types is…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Tianyi Zhao , Kai Cao , Jiawen Yao , Isabella Nogues , Le Lu , Lingyun Huang , Jing Xiao , Zhaozheng Yin , Ling Zhang

Organ segmentation is a prerequisite for a computer-aided diagnosis (CAD) system to detect pathologies and perform quantitative analysis. For anatomically high-variability abdominal organs such as the pancreas, previous segmentation works…

Computer Vision and Pattern Recognition · Computer Science 2014-08-01 Amal Farag , Le Lu , Evrim Turkbey , Jiamin Liu , Ronald M. Summers

Accurate automatic organ segmentation is an important yet challenging problem for medical image analysis. The pancreas is an abdominal organ with very high anatomical variability. This inhibits traditional segmentation methods from…

Computer Vision and Pattern Recognition · Computer Science 2016-06-28 Holger R. Roth , Le Lu , Amal Farag , Andrew Sohn , Ronald M. Summers

Purpose: Understanding how the pancreas changes is critical for detecting deviations in type 2 diabetes and other pancreatic disease. We measure pancreas size and shape using morphological measurements from ages 0 to 90. Our goals are to 1)…

Robust automated organ segmentation is a prerequisite for computer-aided diagnosis (CAD), quantitative imaging analysis and surgical assistance. For high-variability organs such as the pancreas, previous approaches report undesirably low…

Computer Vision and Pattern Recognition · Computer Science 2016-03-08 Amal Farag , Le Lu , Holger R. Roth , Jiamin Liu , Evrim Turkbey , Ronald M. Summers

Purposes: This study aimed to develop a computed tomography (CT)-based multi-organ segmentation model for delineating organs-at-risk (OARs) in pediatric upper abdominal tumors and evaluate its robustness across multiple datasets. Materials…

Respiratory motion and the associated deformations of abdominal organs and tumors are essential information in clinical applications. However, inter- and intra-patient multi-organ deformations are complex and have not been statistically…

Computer Vision and Pattern Recognition · Computer Science 2020-11-04 Megumi Nakao , Mitsuhiro Nakamura , Takashi Mizowaki , Tetsuya Matsuda

Pancreatic tumor segmentation in contrast-enhanced computed tomography (CT) is clinically important yet technically challenging: lesions are often small, heterogeneous, and easily confused with surrounding soft tissue, and models that…

Quantitative Methods · Quantitative Biology 2026-04-24 Sunny Joy Ma , Xiang Ma

Early detection improves prognosis in pancreatic ductal adenocarcinoma (PDAC) but is challenging as lesions are often small and poorly defined on contrast-enhanced computed tomography scans (CE-CT). Deep learning can facilitate PDAC…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Natália Alves , Megan Schuurmans , Geke Litjens , Joeran S. Bosma , John Hermans , Henkjan Huisman

Automatic segmentation of an organ and its cystic region is a prerequisite of computer-aided diagnosis. In this paper, we focus on pancreatic cyst segmentation in abdominal CT scan. This task is important and very useful in clinical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-23 Yuyin Zhou , Lingxi Xie , Elliot K. Fishman , Alan L. Yuille

Human body is a complex dynamic system composed of various sub-dynamic parts. Especially, thoracic and abdominal organs have complex internal shape variations with different frequencies by various reasons such as respiration with fast…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Seyoun Park , Elliot K. Fishman , Alan L. Yuille

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers among the population. Screening for PDACs in dynamic contrast-enhanced CT is beneficial for early diagnosis. In this paper, we investigate the problem of automated…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Yingda Xia , Qihang Yu , Wei Shen , Yuyin Zhou , Elliot K. Fishman , Alan L. Yuille
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