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Thalassaemia, triggered by defects in the globin genes, is one of the most common monogenic diseases. The beta-thalassaemia carrier state is clinically asymptomatic, thus, making it onerous to diagnose. The current gold standard technique…

Thalassemia, a blood disorder and one of the most prevalent hereditary genetic disorders worldwide, is often caused by copy number variations (CNVs) in the hemoglobin genes. This disorder has incredible diversity, with a large number of…

Genomics · Quantitative Biology 2025-04-15 Austin Talbot , Alex Kotlar , Lavanya Rishishiwar , Yue Ke

Thalassemia is a heritable blood disorder which is the outcome of a genetic defect causing lack of production of hemoglobin polypeptide chains. However, there is less understanding of the precise frequency as well as sharing in these areas.…

Machine Learning · Computer Science 2024-07-01 Hemn Barzan Abdalla , Awder Ahmed , Guoquan Li , Nasser Mustafa , Abdur Rashid Sangi

Familial Hypercholesterolemia (FH) is a genetic disorder characterized by elevated levels of Low-Density Lipoprotein (LDL) cholesterol or its associated genes. Early-stage and accurate categorization of FH is of significance allowing for…

Machine Learning · Computer Science 2024-03-19 Sadaf Khademi , Zohreh Hajiakhondi , Golnaz Vaseghi , Nizal Sarrafzadegan , Arash Mohammadi

This study explores the use of Federated Learning (FL) for tuberculosis (TB) diagnosis using chest X-rays in low-resource settings across Africa. FL allows hospitals to collaboratively train AI models without sharing raw patient data,…

Machine Learning · Computer Science 2025-05-21 Jorge Fabila , Lidia Garrucho , Víctor M. Campello , Carlos Martín-Isla , Karim Lekadir

Birth Apshyxia (BA) is a severe condition characterized by insufficient supply of oxygen to a newborn during the delivery. BA is one of the primary causes of neonatal death in the world. Although there has been a decline in neonatal deaths…

Machine Learning · Computer Science 2024-12-03 Pamely Zantou , Blessed Guda , Bereket Retta , Gladys Inabeza , Carlee Joe-Wong , Assane Gueye

Sepsis is a life threatening medical condition that occurs when the body has an extreme response to infection, leading to widespread inflammation, organ failure, and potentially death. Because sepsis can worsen rapidly, early detection is…

Machine Learning · Computer Science 2025-05-07 Oyindolapo O. Komolafe , Zhimin Mei , David Morales Zarate , Gregory William Spangenberg

Cardiovascular diseases (CVD) are the leading cause of death globally, and early detection can significantly improve outcomes for patients. Machine learning (ML) models can help diagnose CVDs early, but their performance is limited by the…

Machine Learning · Computer Science 2023-08-29 Sricharan Donkada , Seyedamin Pouriyeh , Reza M. Parizi , Meng Han , Nasrin Dehbozorgi , Nazmus Sakib , Quan Z. Sheng

Intracranial hemorrhage, bleeding that occurs inside the cranium, is a serious health problem requiring rapid and often intensive medical treatment. Such a condition is traditionally diagnosed by highly-trained specialists analyzing…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Utkarsh Chandra Srivastava , Anshuman Singh , K. Sree Kumar

Federated learning (FL) is a novel distributed machine learning paradigm that enables participants to collaboratively train a centralized model with privacy preservation by eliminating the requirement of data sharing. In practice, FL often…

Machine Learning · Computer Science 2024-03-05 Wei Guo , Fuzhen Zhuang , Xiao Zhang , Yiqi Tong , Jin Dong

Tuberculosis (TB) is caused by the bacterium Mycobacterium tuberculosis, primarily affecting the lungs. Early detection is crucial for improving treatment effectiveness and reducing transmission risk. Artificial intelligence (AI),…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 A. A. G. Yogi Pramana , Faiz Ihza Permana , Muhammad Fazil Maulana , Dzikri Rahadian Fudholi

Federated learning (FL) has emerged with increasing popularity to collaborate distributed medical institutions for training deep networks. However, despite existing FL algorithms only allow the supervised training setting, most hospitals in…

Computer Vision and Pattern Recognition · Computer Science 2021-06-17 Quande Liu , Hongzheng Yang , Qi Dou , Pheng-Ann Heng

Federated learning (FL) has been introduced to the healthcare domain as a decentralized learning paradigm that allows multiple parties to train a model collaboratively without privacy leakage. However, most previous studies have assumed…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Zhipeng Deng , Luyang Luo , Hao Chen

While it is well known that population differences from genetics, sex, race, and environmental factors contribute to disease, AI studies in medicine have largely focused on locoregional patient cohorts with less diverse data sources. Such…

In recent decades, attention has been directed at anemia classification for various medical purposes, such as thalassemia screening and predicting iron deficiency anemia (IDA). In this study, a new method has been successfully tested for…

Machine Learning · Computer Science 2020-04-02 Sultan Noman Qasem , Amir Mosavi

Federated Learning (FL) is an evolving machine learning method in which multiple clients participate in collaborative learning without sharing their data with each other and the central server. In real-world applications such as hospitals…

Computer Vision and Pattern Recognition · Computer Science 2023-08-02 Hussain Ahmad Madni , Rao Muhammad Umer , Gian Luca Foresti

Machine learning in medical research, by nature, needs careful attention on obeying the regulations of data privacy, making it difficult to train a machine learning model over gathered data from different medical centers. Failure of…

Machine Learning · Computer Science 2021-10-19 Jun Luo , Shandong Wu

Federated learning (FL) is a promising technique that enables a large amount of edge computing devices to collaboratively train a global learning model. Due to privacy concerns, the raw data on devices could not be available for centralized…

Machine Learning · Computer Science 2020-11-24 Miao Yang , Akitanoshou Wong , Hongbin Zhu , Haifeng Wang , Hua Qian

Cardiovascular diseases (CVDs) are currently the leading cause of death worldwide, highlighting the critical need for early diagnosis and treatment. Machine learning (ML) methods can help diagnose CVDs early, but their performance relies on…

Signal Processing · Electrical Eng. & Systems 2024-11-12 Yukun Zhang , Guanzhong Chen , Zenglin Xu , Jianyong Wang , Dun Zeng , Junfan Li , Jinghua Wang , Yuan Qi , Irwin King

In this paper we discuss a new method for detecting leukemia in microscopic blood smear images using deep neural networks to diagnose leukemia early in blood. leukemia is considered one of the most dangerous mortality causes for a human…

Image and Video Processing · Electrical Eng. & Systems 2023-01-10 Abdelmageed Ahmed , Alaa Nagy , Ahmed Kamal , Daila Farghl
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