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Biomarkers play a central role in medicine's gradual progress towards proactive, personalized precision diagnostics and interventions. However, finding biomarkers that provide very early indicators of a change in health status, for example…

BACKGROUND: Breast cancer has emerged as one of the most prevalent cancers among women leading to a high mortality rate. Due to the heterogeneous nature of breast cancer, there is a need to identify differentially expressed genes associated…

Machine Learning · Computer Science 2021-11-30 Sheetal Rajpal , Ankit Rajpal , Manoj Agarwal , Naveen Kumar

As restricted quantum computers are slowly becoming a reality, the search for meaningful first applications intensifies. In this domain, one of the more investigated approaches is the use of a special type of quantum circuit - a so-called…

Quantum Physics · Physics 2022-11-08 Charles Moussa , Jan N. van Rijn , Thomas Bäck , Vedran Dunjko

Biomarker discovery is vital in advancing personalized medicine, offering insights into disease diagnosis, prognosis, and therapeutic efficacy. Traditionally, the identification and validation of biomarkers heavily depend on extensive…

Machine Learning · Computer Science 2024-09-25 Wangyang Ying , Dongjie Wang , Xuanming Hu , Ji Qiu , Jin Park , Yanjie Fu

This study investigates the application of quantum neural networks (QNNs) for propensity score estimation to address selection bias in comparing survival outcomes between laparoscopic and open surgical techniques in a cohort of 1177…

Quantum Physics · Physics 2025-06-26 Vojtěch Novák , Ivan Zelinka , Lenka Přibylová , Lubomír Martínek

Quantum machine learning offers a promising new paradigm for computational biology by leveraging quantum mechanical principles to enhance cancer classification, biomarker discovery, and bioinformatics diagnostics. In this study, we apply…

Genomics · Quantitative Biology 2026-04-22 Mandeep Kaur Saggi , Amandeep Singh Bhatia , Humaira Gowher , Sabre Kais

Deep convolutional neural networks comprise a subclass of deep neural networks (DNN) with a constrained architecture that leverages the spatial and temporal structure of the domain they model. Convolutional networks achieve the best…

Machine Learning · Computer Science 2015-10-13 Izhar Wallach , Michael Dzamba , Abraham Heifets

The discovery of important biomarkers is a significant step towards understanding the molecular mechanisms of carcinogenesis; enabling accurate diagnosis for, and prognosis of, a certain cancer type. Before recommending any diagnosis,…

Quantitative Methods · Quantitative Biology 2019-09-11 Md. Rezaul Karim , Michael Cochez , Oya Beyan , Stefan Decker , Christoph Lange

Identifying measurable genetic indicators (or biomarkers) of a specific condition of a biological system is a key element of precision medicine. Indeed it allows to tailor diagnostic, prognostic and treatment choice to individual…

Machine Learning · Statistics 2016-12-16 Chloé-Agathe Azencott

In this work, we propose the BioNetExplorer framework to systematically generate and explore multiple DNN architectures for bio-signal processing in wearables. Our framework adapts key neural architecture parameters to search for an…

Signal Processing · Electrical Eng. & Systems 2021-09-08 Bharath Srinivas Prabakaran , Asima Akhtar , Semeen Rehman , Osman Hasan , Muhammad Shafique

Artificial intelligence and machine learning paves the way to achieve greater technical feats. In this endeavor to hone these techniques, quantum machine learning is budding to serve as an important tool. Using the techniques of deep…

Despite great advances, molecular cancer pathology is often limited to the use of a small number of biomarkers rather than the whole transcriptome, partly due to computational challenges. Here, we introduce a novel architecture of Deep…

Machine Learning · Statistics 2019-08-14 Behrooz Azarkhalili , Ali Saberi , Hamidreza Chitsaz , Ali Sharifi-Zarchi

This study explores the application of Quantum Convolutional Neural Networks (QCNNs) for brain tumor classification using MRI images, leveraging quantum computing for enhanced computational efficiency. A dataset of 3,264 MRI images,…

DNA microarray technology enables the simultaneous measurement of expression levels of thousands of genes, thereby facilitating the understanding of the molecular mechanisms underlying complex diseases such as brain tumors and the…

Machine Learning · Computer Science 2025-08-29 Emine Akpinar , Batuhan Hangun , Murat Oduncuoglu , Oguz Altun , Onder Eyecioglu , Zeynel Yalcin

Identification of cancer driver genes is fundamental for the development of targeted therapeutic interventions. The integration of mutational profiles with protein-protein interaction (PPI) networks offers a promising avenue for their…

Quantum Physics · Physics 2025-11-05 Patricia Marques , Andreas Wichert , Duarte Magano , Bruno Coutinho

In recent years, machine learning and deep learning have driven advances in domains such as image classification, speech recognition, and anomaly detection by leveraging multi-layer neural networks to model complex data. Simultaneously,…

Quantum Physics · Physics 2025-11-25 Hibah Agha , Samuel Yen-Chi Chen , Huan-Hsin Tseng , Shinjae Yoo

The rapid expansion of biomolecular datasets presents significant challenges for computational biology. Quantum computing emerges as a promising solution to address these complexities. This study introduces a novel quantum framework for…

Chemical Physics · Physics 2025-07-02 Don Roosan , Rubayat Khan , Saif Nirzhor , Tiffany Khou , Fahmida Hai

Recent advances in the fields of deep learning and quantum computing have paved the way for innovative developments in artificial intelligence. In this manuscript, we leverage these cutting-edge technologies to introduce a novel model that…

Emerging Technologies · Computer Science 2025-05-06 Eva Andrés , Manuel Pegalajar Cuéllar , Gabriel Navarro

We present a case study and forward-looking perspective on co-design for hybrid quantum-classical algorithms, centered on the goal of empirical quantum advantage (EQA), which we define as a measurable performance gain using quantum hardware…

Photonic quantum computing is a promising platform for scalable quantum machine learning, but designing effective hybrid architectures remains challenging under hardware and optimization constraints. Existing approaches rely on manually…

Quantum Physics · Physics 2026-05-22 Farah Elnakhal , Alberto Marchisio , Nouhaila Innan , Gabriel Falcao , Muhammad Shafique
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