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Biological neurons exhibit remarkable intelligence: they maintain internal states, communicate selectively with other neurons, and self-organize into complex graphs rather than rigid hierarchical layers. What if artificial intelligence…

Machine Learning · Computer Science 2025-12-01 Antoine Salomon

Brain connectivity analysis is crucial for understanding brain structure and neurological function, shedding light on the mechanisms of mental illness. To study the association between individual brain connectivity networks and the clinical…

We present a framework to recognize Parkinson's disease (PD) through an English pangram utterance speech collected using a web application from diverse recording settings and environments, including participants' homes. Our dataset includes…

Modeling invasive neural spike data is fundamental to advancing high-performance brain-computer interfaces (BCIs). However, existing approaches face critical challenges, including limited-scale heterogeneous data, cross-domain distribution…

Neural and Evolutionary Computing · Computer Science 2026-05-04 Binjie Hong , Rui Xiong , Liyuan Han , Tielin Zhang

Age is an important variable to describe the expected brain's anatomy status across the normal aging trajectory. The deviation from that normative aging trajectory may provide some insights into neurological diseases. In neuroimaging,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Identification of human genes involved in the aging process is critical due to the incidence of many diseases with age. A state-of-the-art approach for this purpose infers a weighted dynamic aging-specific subnetwork by mapping gene…

Molecular Networks · Quantitative Biology 2022-05-27 Qi Li , Khalique Newaz , Tijana Milenković

Representing dynamical systems through data-driven universal spaces has proven effective; however, achieving this universality for human brain activity remains a significant challenge, further aggravated by diverse cognitive states and…

Quantitative Methods · Quantitative Biology 2026-05-06 Ronghua Zheng , Chengyuan Qian , Weiyang Ding

Omics data analysis is crucial for studying complex diseases, but its high dimensionality and heterogeneity challenge classical statistical and machine learning methods. Graph neural networks have emerged as promising alternatives, yet the…

Attention Deficit Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental condition; however, its neurobiological diagnosis remains challenging due to the lack of reliable imaging-based biomarkers, particularly anatomical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Qurat Ul Ain , Alptekin Temizel , Soyiba Jawed

Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…

Neurons and Cognition · Quantitative Biology 2022-04-25 Rong Wang , Mianxin Liu , Xinhong Cheng , Ying Wu , Andrea Hildebrandt , Changsong Zhou

We investigate combining imaging and shape features extracted from MRI for the clinically relevant tasks of brain age prediction and Alzheimer's disease classification. Our proposed model fuses ResNet-extracted image embeddings with shape…

Computer Vision and Pattern Recognition · Computer Science 2025-01-15 Nairouz Shehata , Carolina Piçarra , Ben Glocker

Brain aging is a complex and dynamic process, leading to functional and structural changes in the brain. These changes could lead to the increased risk of neurodegenerative diseases and cognitive decline. Accurate brain-age estimation…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Saadat Behzadi , Danial Sharifrazi , Roohallah Alizadehsani , Mojtaba Lotfaliany , Mohammadreza Mohebbi

Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…

Artificial Intelligence · Computer Science 2023-02-24 Mianxin Liu , Jingyang Zhang , Yao Wang , Yan Zhou , Fang Xie , Qihao Guo , Feng Shi , Han Zhang , Qian Wang , Dinggang Shen

The brain's biological age has been considered as a promising candidate for a neurologically significant biomarker. However, recent results based on longitudinal magnetic resonance imaging data have raised questions on its interpretation. A…

Neurons and Cognition · Quantitative Biology 2023-10-12 Lukas AW Gemein , Robin T Schirrmeister , Joschka Boedecker , Tonio Ball

Multivariate regression models for age estimation are a powerful tool for assessing abnormal brain morphology associated to neuropathology. Age prediction models are built on cohorts of healthy subjects and are built to reflect normal aging…

Computer Vision and Pattern Recognition · Computer Science 2018-04-05 Benjamin Gutierrez Becker , Tassilo Klein , Christian Wachinger

Parkinson's disease (PD) is one of the most common neurodegenerative disorder. PD telemonitoring emerges as a novel assessment modality enabling self-administered at-home tests of Unified Parkinson's Disease Rating Scale (UPDRS) scores,…

Machine Learning · Computer Science 2025-10-03 Ziming Tang , Chengbin Hou , Tianyu Zhang , Bangxu Tian , Jinbao Wang , Hairong Lv

With the rise in importance of personalized medicine, we trained personalized neural networks to detect tumor progression in longitudinal datasets. The model was evaluated on two datasets with a total of 64 scans from 32 patients diagnosed…

Machine Learning · Computer Science 2022-10-28 Christian Strack , Kelsey L. Pomykala , Heinz-Peter Schlemmer , Jan Egger , Jens Kleesiek

Physics-informed neural networks (PINNs) [4, 10] are an approach for solving boundary value problems based on differential equations (PDEs). The key idea of PINNs is to use a neural network to approximate the solution to the PDE and to…

Numerical Analysis · Mathematics 2023-05-23 Victorita Dolean , Alexander Heinlein , Siddhartha Mishra , Ben Moseley

In this work, we present a deep convolutional pyramid person matching network (PPMN) with specially designed Pyramid Matching Module to address the problem of person re-identification. The architecture takes a pair of RGB images as input,…

Computer Vision and Pattern Recognition · Computer Science 2018-03-08 Chaojie Mao , Yingming Li , Zhongfei Zhang , Yaqing Zhang , Xi Li

Age is one of the major known risk factors for Alzheimer's Disease (AD). Detecting AD early is crucial for effective treatment and preventing irreversible brain damage. Brain age, a measure derived from brain imaging reflecting structural…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Jay Shah , Md Mahfuzur Rahman Siddiquee , Yi Su , Teresa Wu , Baoxin Li
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