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Reliability-oriented sensitivity analysis aims at combining both reliability and sensitivity analyses by quantifying the influence of each input variable of a numerical model on a quantity of interest related to its failure. In particular,…

Statistics Theory · Mathematics 2022-10-25 Julien Demange-Chryst , François Bachoc , Jérôme Morio

With X-ray radiation protection and dose management constantly gaining interest in interventional radiology, novel procedures often undergo prospective dose studies using anthropomorphic phantoms to determine expected dose values. Due to…

Performing (variance-based) global sensitivity analysis (GSA) with dependent inputs has recently benefited from cooperative game theory concepts.By using this theory, despite the potential correlation between the inputs, meaningful…

Statistics Theory · Mathematics 2022-10-25 Margot Herin , Marouane Il Idrissi , Vincent Chabridon , Bertrand Iooss

The Shapley effects are global sensitivity indices: they quantify the impact of each input variable on the output variable in a model. In this work, we suggest new estimators of these sensitivity indices. When the input distribution is…

Statistics Theory · Mathematics 2020-02-14 Baptiste Broto , François Bachoc , Marine Depecker

Shapley effects are attracting increasing attention as sensitivity measures. When the value function is the conditional variance, they account for the individual and higher order effects of a model input. They are also well defined under…

Computation · Statistics 2021-10-13 Elmar Plischke , Giovanni Rabitti , Emanuele Borgonovo

The global sensitivity analysis of a numerical model aims to quantify, by means of sensitivity indices estimate, the contributions of each uncertain input variable to the model output uncertainty. The so-called Sobol' indices, which are…

Statistics Theory · Mathematics 2019-11-26 Bertrand Iooss , Clémentine Prieur

When using machine learning techniques in decision-making processes, the interpretability of the models is important. Shapley additive explanation (SHAP) is one of the most promising interpretation methods for machine learning models.…

Machine Learning · Computer Science 2022-08-08 Yasunobu Nohara , Toyoshi Inoguchi , Chinatsu Nojiri , Naoki Nakashima

Background: Spectral shaping is a computed tomography (CT) dose optimization technique that adjusts source voltage and filtration to reduce patient radiation exposure without compromising image quality. Traditionally, radiation dose has…

This paper presents an approach for estimating Shapley effects for use as global sensitivity metrics to quantify the relative importance of uncertain model parameters. Polynomial Chaos expansion, a well established approach for developing…

Applications · Statistics 2023-01-12 Adrian Stein , Tarunraj Singh

Computed tomography (CT) scans are a major source of medical radiation exposure worldwide. In countries like China, the frequency of CT scans has grown rapidly, particularly in routine physical examinations where chest CT scans are…

Medical Physics · Physics 2025-04-10 Zirui Ye , Bei Yao , Haoran Zheng , Li Tao , Ripeng Wang , Yankui Chang , Zhi Chen , Yingming Zhao , Wei Wei , Xie George Xu

Segmentation is the identification of anatomical regions of interest, such as organs, tissue, and lesions, serving as a fundamental task in computer-aided diagnosis in medical imaging. Although deep learning models have achieved remarkable…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Tianyi Ren , Daniel Low , Pittra Jaengprajak , Juampablo Heras Rivera , Jacob Ruzevick , Mehmet Kurt

Dosimetry audits are carried out to determine how well radiotherapy is delivered to the patient. It is also used to understand the uncertainty introduced into the measurement result when using different computational models. As measurement…

Dose volume histograms are a useful tool in state-of-the-art radiotherapy planning, and it is essential to be aware of their limitations. Dose distributions computed by treatment planning systems are affected by several sources of…

Medical Physics · Physics 2007-06-13 Francisco Cutanda-Henriquez , Silvia Vargas-Castrillon

Recently, Yamashita et al. reported direct measurements of ionizing radiation doses to individual organs in postmortem (using OSL dosimetry) that were exposed in the most frequent clinical CT scan protocols, corresponding to the whole body,…

In global sensitivity analysis, the well known Sobol' sensitivity indices aim to quantify how the variance in the output of a mathematical model can be apportioned to the different variances of its input random variables. These indices are…

Statistics Theory · Mathematics 2018-01-11 Nazih Benoumechiara , Kevin Elie-Dit-Cosaque

We emphasize the importance of asking the right question when interpreting the decisions of a learning model. We discuss a natural extension of the theoretical machinery from Janzing et. al. 2020, which answers the question "Why did my…

Machine Learning · Statistics 2020-12-11 Debraj Basu

Shapley effects are a particularly interpretable approach to assessing how a function depends on its various inputs. The existing literature contains various estimators for this class of sensitivity indices in the context of nonparametric…

Methodology · Statistics 2025-05-27 Akira Horiguchi , Matthew T. Pratola

Global sensitivity analysis aims at measuring the relative importance of different variables or groups of variables for the variability of a quantity of interest. Among several sensitivity indices, so-called Shapley effects have recently…

Computation · Statistics 2021-04-27 Takashi Goda

In this paper, we address the estimation of the sensitivity indices called "Shapley eects". These sensitivity indices enable to handle dependent input variables. The Shapley eects are generally dicult to estimate, but they are easily…

Statistics Theory · Mathematics 2020-06-04 Baptiste Broto , François Bachoc , Marine Depecker , Jean-Marc Martinez

Reliability-oriented sensitivity analysis methods have been developed for understanding the influence of model inputs relative to events which characterize the failure of a system (e.g., a threshold exceedance of the model output). In this…

Statistics Theory · Mathematics 2025-07-04 Marouane Il Idrissi , Vincent Chabridon , Bertrand Iooss
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