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Medical image segmentation is important for computer-aided diagnosis. Good segmentation demands the model to see the big picture and fine details simultaneously, i.e., to learn image features that incorporate large context while keep high…

Image and Video Processing · Electrical Eng. & Systems 2021-06-03 Shaohua Li , Xiuchao Sui , Xiangde Luo , Xinxing Xu , Yong Liu , Rick Goh

Convolutional neural networks (CNNs) achieved the state-of-the-art performance in medical image segmentation due to their ability to extract highly complex feature representations. However, it is argued in recent studies that traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Zhendi Gong , Andrew P. French , Guoping Qiu , Xin Chen

Pixel-wise segmentation is one of the most data and annotation hungry tasks in our field. Providing representative and accurate annotations is often mission-critical especially for challenging medical applications. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2021-04-28 Simon Reiß , Constantin Seibold , Alexander Freytag , Erik Rodner , Rainer Stiefelhagen

Understanding how segmentation performance scales with training data is fundamental for developing data-efficient medical AI systems. In this study, we systematically revisit data scaling behavior across 15 anatomical segmentation tasks…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yuetan Chu , Zhongyi Han , Gongning Luo , Xin Gao

Medical image analysis requires substantial labeled data for model training, yet expert annotation is expensive and time-consuming. Active learning (AL) addresses this challenge by strategically selecting the most informative samples for…

Image and Video Processing · Electrical Eng. & Systems 2026-03-06 Ifrat Ikhtear Uddin , Longwei Wang , Xiao Qin , Yang Zhou , KC Santosh

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

Semantic segmentation of microscopy cell images by deep learning is a significant technique. We considered that the Transformers, which have recently outperformed CNNs in image recognition, could also be improved and developed for cell…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Hinako Mitsuoka , Kazuhiro Hotta

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

Annotation of medical images has been a major bottleneck for the development of accurate and robust machine learning models. Annotation is costly and time-consuming and typically requires expert knowledge, especially in the medical domain.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Holger Roth , Ling Zhang , Dong Yang , Fausto Milletari , Ziyue Xu , Xiaosong Wang , Daguang Xu

Self-supervised pre-training has become the priory choice to establish reliable neural networks for automated recognition of massive biomedical microscopy images, which are routinely annotation-free, without semantics, and without guarantee…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Wei Chen , Chen Li , Dan Chen , Xin Luo

The field of medical image segmentation is hindered by the scarcity of large, publicly available annotated datasets. Not all datasets are made public for privacy reasons, and creating annotations for a large dataset is time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Iira Häkkinen , Iaroslav Melekhov , Erik Englesson , Hossein Azizpour , Juho Kannala

Multi-modal MR imaging is routinely used in clinical practice to diagnose and investigate brain tumors by providing rich complementary information. Previous multi-modal MRI segmentation methods usually perform modal fusion by concatenating…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Zhaohu Xing , Lequan Yu , Liang Wan , Tong Han , Lei Zhu

The Segment Anything Model (SAM) has recently gained popularity in the field of image segmentation due to its impressive capabilities in various segmentation tasks and its prompt-based interface. However, recent studies and individual…

Computer Vision and Pattern Recognition · Computer Science 2024-01-01 Junde Wu , Wei Ji , Yuanpei Liu , Huazhu Fu , Min Xu , Yanwu Xu , Yueming Jin

The segmentation of optic disc(OD) and optic cup(OC) from fundus images is an important fundamental task for glaucoma diagnosis. In the clinical practice, it is often necessary to collect opinions from multiple experts to obtain the final…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Junde Wu , Huihui Fang , Fangxin Shang , Zhaowei Wang , Dalu Yang , Wenshuo Zhou , Yehui Yang , Yanwu Xu

Recently, deep learning enabled the accurate segmentation of various diseases in medical imaging. These performances, however, typically demand large amounts of manual voxel annotations. This tedious process for volumetric data becomes more…

The goal of this paper is to interactively refine the automatic segmentation on challenging structures that fall behind human performance, either due to the scarcity of available annotations or the difficulty nature of the problem itself,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-28 Wentao Liu , Chaofan Ma , Yuhuan Yang , Weidi Xie , Ya Zhang

Deformable image registration is a fundamental requirement for medical image analysis. Recently, transformers have been widely used in deep learning-based registration methods for their ability to capture long-range dependency via…

Image and Video Processing · Electrical Eng. & Systems 2024-12-25 Mingyuan Meng , Michael Fulham , Lei Bi , Jinman Kim

Transformers have recently shown promise for medical image applications, leading to an increasing interest in developing such models for medical image registration. Recent advancements in designing registration Transformers have focused on…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Junyu Chen , Yihao Liu , Yufan He , Yong Du

Unsupervised anomaly detection (UAD) presents a complementary alternative to supervised learning for brain tumor segmentation in magnetic resonance imaging (MRI), particularly when annotated datasets are limited, costly, or inconsistent. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Gerard Comas-Quiles , Carles Garcia-Cabrera , Julia Dietlmeier , Noel E. O'Connor , Ferran Marques

Brain tumor segmentation is often based on multiple magnetic resonance imaging (MRI). However, in clinical practice, certain modalities of MRI may be missing, which presents a more difficult scenario. To cope with this challenge, Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Tianyi Liu , Zhaorui Tan , Muyin Chen , Xi Yang , Haochuan Jiang , Kaizhu Huang