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Evolutionary graph theory models the effects of natural selection and random drift on structured populations of competing mutant and non-mutant individuals. Recent studies have found that fixation times in such systems often have…

Populations and Evolution · Quantitative Biology 2019-07-31 David Hathcock , Steven H. Strogatz

In genetics the Moran model describes the neutral evolution of a bi-allelic gene in a population of haploid individuals subjected to mutations. We show in this paper that this model can be mapped into an influence dynamical process on…

Populations and Evolution · Quantitative Biology 2015-03-17 Marcus A. M. de Aguiar , Yaneer Bar-Yam

We study the evolution of the population genealogy in the classic neutral Moran Model of finite size and in discrete time. The stochastic transformations that shape a Moran population can be realized directly on its genealogy and give rise…

Populations and Evolution · Quantitative Biology 2019-02-08 Johannes Wirtz , Thomas Wiehe

The Moran process, as studied by [Lieberman, E., Hauert, C. and Nowak, M. Evolutionary dynamics on graphs. Nature 433, pp. 312-316 (2005)], is a stochastic process modeling the spread of genetic mutations in populations. In this process,…

Populations and Evolution · Quantitative Biology 2021-07-27 Themistoklis Melissourgos , Sotiris Nikoletseas , Christoforos Raptopoulos , Paul Spirakis

The Moran process is a classic stochastic process that models invasion dynamics on graphs. A single "mutant" (e.g., a new opinion, strain, social trait etc.) invades a population of residents spread over the nodes of a graph. The mutant…

Data Structures and Algorithms · Computer Science 2022-04-26 Joachim Brendborg , Panagiotis Karras , Andreas Pavlogiannis , Asger Ullersted Rasmussen , Josef Tkadlec

We consider the Moran model in continuous time with two types, mutation, and selection. We concentrate on the ancestral line and its stationary type distribution. Building on work by Fearnhead (J. Appl. Prob. 39 (2002), 38-54) and Taylor…

Populations and Evolution · Quantitative Biology 2013-12-09 Sandra Kluth , Thiemo Hustedt , Ellen Baake

Consider a population of $N$ individuals, each of them carrying a type in $\mathbb N_0$. The population evolves according to a Moran dynamics with selection and mutation, where an individual of type $k$ has the same selective advantage over…

Probability · Mathematics 2023-12-06 Adrian Gonzalez Casanova , Charline Smadi , Anton Wakolbinger

Evolution occurs in populations of reproducing individuals. In stochastic descriptions of evolutionary dynamics, such as the Moran process, individuals are chosen randomly for birth and for death. If the same type is chosen for both steps,…

Populations and Evolution · Quantitative Biology 2026-01-13 Michal Pecho , Josef Tkadlec , Martin A. Nowak

We consider the spatial Lambda-Fleming-Viot process model for frequencies of genetic types in a population living in R^d, with two types of individuals (0 and 1) and natural selection favouring individuals of type 1. We first prove that the…

Probability · Mathematics 2020-10-01 Alison Etheridge , Amandine Veber , Feng Yu

We ask the question "when will natural selection on a gene in a spatially structured population cause a detectable trace in the patterns of genetic variation observed in the contemporary population?". We focus on the situation in which…

Probability · Mathematics 2016-11-17 Alison Etheridge , Nic Freeman , Sarah Penington , Daniel Straulino

When two (possibly different in distribution) continuous-state branching processes with immigration are present, we study the relative frequency of one of them when the total mass is forced to be constant at a dense set of times. This leads…

Probability · Mathematics 2023-03-14 María Emilia Caballero , Adrián González Casanova , José-Luis Pérez

Mendelian randomization (MR) is a natural experimental design based on the random transmission of genes from parents to offspring. However, this inferential basis is typically only implicit or used as an informal justification. As…

Methodology · Statistics 2023-04-19 Matthew J Tudball , George Davey Smith , Qingyuan Zhao

Resources are rarely distributed uniformly within a population. Heterogeneity in the concentration of a drug, the quality of breeding sites, or wealth can all affect evolutionary dynamics. In this study, we represent a collection of…

Populations and Evolution · Quantitative Biology 2022-02-18 Kamran Kaveh , Alex McAvoy , Krishnendu Chatterjee , Martin A. Nowak

The spread of an advantageous mutation through a population is of fundamental interest in population genetics. While the classical Moran model is formulated for a well-mixed population, it has long been recognized that in real-world…

Populations and Evolution · Quantitative Biology 2022-09-27 Jasmine Foo , Einar Bjarki Gunnarsson , Kevin Leder , David Sivakoff

Evolutionary dynamics on graphs can lead to many interesting and counterintuitive findings. We study the Moran process, a discrete time birth-death process, that describes the invasion of a mutant type into a population of wild-type…

Populations and Evolution · Quantitative Biology 2015-04-23 Laura Hindersin , Arne Traulsen

We consider a Moran-type model of cultural evolution, which describes how traits emerge, are transmitted, and get lost in populations. Our analysis focuses on the underlying cultural genealogies; they were first described by Aguilar and…

Populations and Evolution · Quantitative Biology 2026-02-04 Joe Yuichiro Wakano , Hisashi Ohtsuki , Yutaka Kobayashi , Ellen Baake

We examine birth--death processes with state dependent transition probabilities and at least one absorbing boundary. In evolution, this describes selection acting on two different types in a finite population where reproductive events occur…

Populations and Evolution · Quantitative Biology 2010-10-12 Philipp M. Altrock , Chaytanya S. Gokhale , Arne Traulsen

Evolutionary dynamics have been traditionally studied in the context of homogeneous populations, mainly described my the Moran process. Recently, this approach has been generalized in \cite{LHN} by arranging individuals on the nodes of a…

Discrete Mathematics · Computer Science 2012-06-22 George B. Mertzios , Sotiris Nikoletseas , Christoforos Raptopoulos , Paul G. Spirakis

We review recent progress on ancestral processes related to mutation-selection models, both in the deterministic and the stochastic setting. We mainly rely on two concepts, namely, the killed ancestral selection graph and the pruned…

Probability · Mathematics 2020-03-17 Ellen Baake , Anton Wakolbinger

Broom and Rycht\'{a}\v{r} [Proc. R. Soc. A (2008) 464, 2609--2627] found an exact solution for the fixation probabilities of the Moran process for a structured population, in which the interaction structure among individuals is given by the…

Populations and Evolution · Quantitative Biology 2020-03-19 Evandro P. de Souza , Armando G. M. Neves