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Automated interpretation of ultrasound imaging of the heart (echocardiograms) could improve the detection and treatment of aortic stenosis (AS), a deadly heart disease. However, existing deep learning pipelines for assessing AS from…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zhe Huang , Xiaowei Yu , Benjamin S. Wessler , Michael C. Hughes

Acute aortic syndrome (AAS) is a group of life threatening conditions of the aorta. We have developed an end-to-end automatic approach to detect AAS in computed tomography (CT) images. Our approach consists of two steps. At first, we…

Computer Vision and Pattern Recognition · Computer Science 2020-04-06 Manikanta Srikar Yellapragada , Yiting Xie , Benedikt Graf , David Richmond , Arun Krishnan , Arkadiusz Sitek

Coronary artery stenosis is a leading cause of cardiovascular disease, diagnosed by analyzing the coronary arteries from multiple angiography views. Although numerous deep-learning models have been proposed for stenosis detection from a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Nikola Cenikj , Özgün Turgut , Alexander Müller , Alexander Steger , Jan Kehrer , Marcus Brugger , Daniel Rueckert , Eimo Martens , Philip Müller

Semi-supervised image classification has shown substantial progress in learning from limited labeled data, but recent advances remain largely untested for clinical applications. Motivated by the urgent need to improve timely diagnosis of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-03 Zhe Huang , Gary Long , Benjamin Wessler , Michael C. Hughes

Aortic stenosis (AS) is a life-threatening condition caused by a narrowing of the aortic valve, leading to impaired blood flow. Despite its high prevalence, access to echocardiography (echo), the gold-standard diagnostic tool, is often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Armin Saadat , Nima Hashemi , Hooman Vaseli , Michael Y. Tsang , Christina Luong , Michiel Van de Panne , Teresa S. M. Tsang , Purang Abolmaesumi

Aortic stenosis (AS) is a common heart valve disease that requires accurate and timely diagnosis for appropriate treatment. Most current automatic AS severity detection methods rely on black-box models with a low level of trustworthiness,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Hooman Vaseli , Ang Nan Gu , S. Neda Ahmadi Amiri , Michael Y. Tsang , Andrea Fung , Nima Kondori , Armin Saadat , Purang Abolmaesumi , Teresa S. M. Tsang

In the era of digital medicine, medical imaging serves as a widespread technique for early disease detection, with a substantial volume of images being generated and stored daily in electronic patient records. X-ray angiography imaging is a…

Image and Video Processing · Electrical Eng. & Systems 2024-05-01 Hadis Keshavarz , Hossein Sadr

Coronary artery stenosis is a critical health risk, and its precise identification in Coronary Angiography (CAG) can significantly aid medical practitioners in accurately evaluating the severity of a patient's condition. The complexity of…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 In Kyu Lee , Junsup Shin , Yong-Hee Lee , Jonghoe Ku , Hyun-Woo Kim

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

This study presents an application of machine learning (ML) methods for detecting the presence of stenoses and aneurysms in the human arterial system. Four major forms of arterial disease -- carotid artery stenosis (CAS), subclavian artery…

Machine Learning · Computer Science 2021-08-03 Gareth Jones , Jim Parr , Perumal Nithiarasu , Sanjay Pant

Aortic stenosis (AS) is the most common valvular heart disease in developed countries. High-fidelity preclinical models can improve AS management by enabling therapeutic innovation, early diagnosis, and tailored treatment planning. However,…

Computational Engineering, Finance, and Science · Computer Science 2024-07-02 Caglar Ozturk , Daniel H. Pak , Luca Rosalia , Debkalpa Goswami , Mary E. Robakowski , Raymond McKay , Christopher T. Nguyen , James S. Duncan , Ellen T. Roche

The evaluation of obstructions (stenosis) in coronary arteries is currently done by a physician's visual assessment of coronary angiography video sequences. It is laborious, and can be susceptible to interobserver variation. Prior studies…

Image and Video Processing · Electrical Eng. & Systems 2021-02-01 Chengyang Zhou , Thao Vy Dinh , Heyi Kong , Jonathan Yap , Khung Keong Yeo , Hwee Kuan Lee , Kaicheng Liang

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Purpose: Congenital heart defect (CHD) is the most common birth defect. Thoracic echocardiography (TTE) can provide sufficient cardiac structure information, evaluate hemodynamics and cardiac function, and is an effective method for atrial…

Image and Video Processing · Electrical Eng. & Systems 2023-06-07 Yiman Liu , Qiming Huang , Xiaoxiang Han , Tongtong Liang , Zhifang Zhang , Lijun Chen , Jinfeng Wang , Angelos Stefanidis , Jionglong Su , Jiangang Chen , Qingli Li , Yuqi Zhang

Stroke is globally a major cause of mortality and morbidity, and hence accurate and rapid diagnosis of stroke is valuable. Retinal fundus imaging reveals the known markers of elevated stroke risk in the eyes, which are retinal venular…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Aysen Degerli , Mika Hilvo , Juha Pajula , Petri Huhtinen , Pekka Jäkälä

Coronary artery disease (CAD) is a leading cause of cardiovascular-related mortality, and accurate stenosis detection is crucial for effective clinical decision-making. Coronary angiography remains the gold standard for diagnosing CAD, but…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Baixiang Huang , Yu Luo , Guangyu Wei , Songyan He , Yushuang Shao , Xueying Zeng

Coronary artery disease leading up to stenosis, the partial or total blocking of coronary arteries, is a severe condition that affects millions of patients each year. Automated identification and classification of stenosis severity from…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Dinis L. Rodrigues , Miguel Nobre Menezes , Fausto J. Pinto , Arlindo L. Oliveira

Automated disease diagnosis using medical image analysis relies on deep learning, often requiring large labeled datasets for supervised model training. Diseases like Acute Myeloid Leukemia (AML) pose challenges due to scarce and costly…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Salome Kazeminia , Max Joosten , Dragan Bosnacki , Carsten Marr

Coronary artery disease(CAD) is the most common type of heart disease and the leading cause of death worldwide[1]. A progressive state of this disease marked by plaque rupture and clot formation in the coronary arteries, also known as an…

Machine Learning · Computer Science 2020-09-29 Atandra Burman , Jitto Titus , David Gbadebo , Melissa Burman

AI-powered stethoscopes offer a promising alternative for screening rheumatic heart disease (RHD), particularly in regions with limited diagnostic infrastructure. Early detection is vital, yet echocardiography, the gold standard tool,…

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