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Recent developments in 3D generative AI enable users to create bespoke 3D models from text or image prompts. However, these approaches provide limited control over spatial structure, making them ill suited for tasks requiring precise…

Human-Computer Interaction · Computer Science 2026-05-21 Faraz Faruqi , Demircan Tas , Arthur Caetano , Niccolò Meniconi , Oğuz Arslan , Misha Sra , Ruofei Du , Stefanie Mueller , Mustafa Doga Dogan

The limited availability of 3D medical image datasets, due to privacy concerns and high collection or annotation costs, poses significant challenges in the field of medical imaging. While a promising alternative is the use of synthesized…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Lingting Zhu , Noel Codella , Dongdong Chen , Zhenchao Jin , Lu Yuan , Lequan Yu

Collecting and annotating datasets for pixel-level semantic segmentation tasks are highly labor-intensive. Data augmentation provides a viable solution by enhancing model generalization without additional real-world data collection.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Huy Che , Dinh-Duy Phan , Duc-Khai Lam

Using recent advances in generative artificial intelligence (AI) brought by diffusion models, this paper introduces a new synergistic method for spectral computed tomography (CT) reconstruction. Diffusion models define a neural network to…

We study how to generate molecule conformations (i.e., 3D structures) from a molecular graph. Traditional methods, such as molecular dynamics, sample conformations via computationally expensive simulations. Recently, machine learning…

Machine Learning · Computer Science 2021-04-01 Minkai Xu , Shitong Luo , Yoshua Bengio , Jian Peng , Jian Tang

Motivation: Thanks to the recent advances in structural biology, nowadays three-dimensional structures of various proteins are solved on a routine basis. A large portion of these contain structural repetitions or internal symmetries. To…

Quantitative Methods · Quantitative Biology 2018-10-30 Guillaume Pagès , Sergei Grudinin

We propose ReMiDi, a novel method for inferring neuronal microstructure as arbitrary 3D meshes using a differentiable diffusion Magnetic Resonance Imaging (dMRI) simulator. We first implemented in PyTorch a differentiable dMRI simulator…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Prathamesh Pradeep Khole , Zahra Kais Petiwala , Shri Prathaa Magesh , Ehsan Mirafzali , Utkarsh Gupta , Jing-Rebecca Li , Andrada Ianus , Razvan Marinescu

Graph-based learned simulators have emerged as a promising approach for simulating physical systems on unstructured meshes, offering speed and generalization across diverse geometries. However, they often struggle with capturing global…

Machine Learning · Computer Science 2025-10-24 Tobias Würth , Niklas Freymuth , Gerhard Neumann , Luise Kärger

Conventional physically based rendering (PBR) pipelines generate photorealistic images through computationally intensive light transport simulations. Although recent deep learning approaches leverage diffusion model priors with geometry…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Shenghao Zhang , Runtao Liu , Christopher Schroers , Yang Zhang

Accurate quantification of the extent of lung pathological patterns (fibrosis, ground-glass opacity, emphysema, consolidation) is prerequisite for diagnosis and follow-up of interstitial lung diseases. However, segmentation is challenging…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Rezkellah Noureddine Khiati , Pierre-Yves Brillet , Radu Ispas , Catalin Fetita

In numerical simulation, structured mesh generation often requires a lot of time and manpower investment. The general scheme for structured quad mesh generation is to find a mapping between the computational domain and the physical domain.…

Computational Engineering, Finance, and Science · Computer Science 2025-03-04 Min Wang , Haisheng Li , Haoxuan Zhang , Xiaoqun Wu , Nan Li

The task of deducing three-dimensional molecular configurations from their two-dimensional graph representations holds paramount importance in the fields of computational chemistry and pharmaceutical development. The rapid advancement of…

Biomolecules · Quantitative Biology 2025-01-09 Bobin Yang , Jie Deng , Zhenghan Chen , Ruoxue Wu

Structural relationships among proteins are important in the study of their evolution as well as in drug design and development. The protein 3D structure has been shown to be effective with respect to classifying proteins. Prior work has…

Biomolecules · Quantitative Biology 2016-02-26 James DeFelice , Vicente M. Reyes

Accurate segmentation of rectal lymph nodes is crucial for the staging and treatment planning of rectal cancer. However, the complexity of the surrounding anatomical structures and the scarcity of annotated data pose significant challenges.…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Weidong Guo , Hantao Zhang , Shouhong Wan , Bingbing Zou , Wanqin Wang , Peiquan Jin

Comprehending the long-timescale dynamics of protein-ligand complexes is very important for drug discovery and structural biology, but it continues to be computationally challenging for large biomolecular systems. We introduce…

Biomolecules · Quantitative Biology 2025-08-26 Rakesh Thakur , Riya Gupta

Recent advances in deep learning have enabled the generation of realistic data by training generative models on large datasets of text, images, and audio. While these models have demonstrated exceptional performance in generating novel and…

Materials Science · Physics 2024-06-17 Izumi Takahara , Kiyou Shibata , Teruyasu Mizoguchi

Extending the success of 2D Large Kernel to 3D perception is challenging due to: 1. the cubically-increasing overhead in processing 3D data; 2. the optimization difficulties from data scarcity and sparsity. Previous work has taken the first…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Tao Lu , Xiang Ding , Haisong Liu , Gangshan Wu , Limin Wang

Generating long-term, coherent, and realistic music-conditioned dance sequences remains a challenging task in human motion synthesis. Existing approaches exhibit critical limitations: motion graph methods rely on fixed template libraries,…

Sound · Computer Science 2025-06-04 Mingyang Huang , Peng Zhang , Bang Zhang

Purpose: Magnetic Resonance Imaging (MRI) enables non-invasive assessment of brain abnormalities during early life development. Permanent magnet scanners operating in the neonatal intensive care unit (NICU) facilitate MRI of sick infants,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-23 Yamin Arefeen , Brett Levac , Bhairav Patel , Chang Ho , Jonathan I. Tamir

Molecule generation, especially generating 3D molecular geometries from scratch (i.e., 3D \textit{de novo} generation), has become a fundamental task in drug designs. Existing diffusion-based 3D molecule generation methods could suffer from…

Machine Learning · Computer Science 2022-09-14 Lei Huang , Hengtong Zhang , Tingyang Xu , Ka-Chun Wong
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