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The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Detecting visual anomalies in diverse, multi-class real-world images is a significant challenge. We introduce \ours, a novel unsupervised multi-class visual anomaly detection framework. It integrates a Latent Diffusion Model (LDM) with a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Samet Hicsonmez , Abd El Rahman Shabayek , Djamila Aouada

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias

Denoising diffusion probabilistic models (DDPMs) have been proven capable of synthesizing high-quality images with remarkable diversity when trained on large amounts of data. Typical diffusion models and modern large-scale conditional…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Jingyuan Zhu , Huimin Ma , Jiansheng Chen , Jian Yuan

Diffusion models have emerged as a prominent technique in generative modeling with neural networks, making their mark in tasks like text-to-image translation and super-resolution. In this tutorial, we provide a comprehensive guide to build…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Harshith Bachimanchi , Giovanni Volpe

Diffusion Probabilistic Models (DPMs) have emerged as the de facto approach for high-fidelity image synthesis, operating diffusion processes on continuous VAE latent, which significantly differ from the text generation methods employed by…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Xiaoping Wu , Jie Hu , Xiaoming Wei

Computational imaging is crucial in many disciplines from autonomous driving to life sciences. However, traditional model-driven and iterative methods consume large computational power and lack scalability for imaging. Deep learning (DL) is…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Weiru Fan , Xiaobin Tang , Yiyi Liao , Da-Wei Wang

Denoising diffusion probabilistic models (DDPMs) have achieved unprecedented success in computer vision. However, they remain underutilized in medical imaging, a field crucial for disease diagnosis and treatment planning. This is primarily…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Hongxu Jiang , Muhammad Imran , Teng Zhang , Yuyin Zhou , Muxuan Liang , Kuang Gong , Wei Shao

Medical image segmentation is a challenging task, made more difficult by many datasets' limited size and annotations. Denoising diffusion probabilistic models (DDPM) have recently shown promise in modelling the distribution of natural…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Margherita Rosnati , Melanie Roschewitz , Ben Glocker

Anomaly detection is an emerging approach in digital pathology for its ability to efficiently and effectively utilize data for disease diagnosis. While supervised learning approaches deliver high accuracy, they rely on extensively annotated…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Keunho Byeon , Jinsol Song , Anh Nguyen , Sangjeong Ahn , Sung Hak Lee , Jin Tae Kwak

Diffusion-based generative models (DBGMs) perturb data to a target noise distribution and reverse this process to generate samples. The choice of noising process, or inference diffusion process, affects both likelihoods and sample quality.…

Machine Learning · Computer Science 2023-03-06 Raghav Singhal , Mark Goldstein , Rajesh Ranganath

The performance of anomaly inspection in industrial manufacturing is constrained by the scarcity of anomaly data. To overcome this challenge, researchers have started employing anomaly generation approaches to augment the anomaly dataset.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Ying Jin , Jinlong Peng , Qingdong He , Teng Hu , Jiafu Wu , Hao Chen , Haoxuan Wang , Wenbing Zhu , Mingmin Chi , Jun Liu , Yabiao Wang

Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Xutao Guo , Yanwu Yang , Chenfei Ye , Shang Lu , Yang Xiang , Ting Ma

Magnetic resonance imaging (MRI) is a vital diagnostic tool, but its inherently long acquisition times reduce clinical efficiency and patient comfort. Recent advancements in deep learning, particularly diffusion models, have improved…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Yuxuan Zhang , Jinkui Hao , Bo Zhou

Diffusion models are powerful generative models that map noise to data using stochastic processes. However, for many applications such as image editing, the model input comes from a distribution that is not random noise. As such, diffusion…

Computer Vision and Pattern Recognition · Computer Science 2023-12-06 Linqi Zhou , Aaron Lou , Samar Khanna , Stefano Ermon

Diffusion models have recently exhibited remarkable abilities to synthesize striking image samples since the introduction of denoising diffusion probabilistic models (DDPMs). Their key idea is to disrupt images into noise through a fixed…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Zijian Zhang , Zhou Zhao , Jun Yu , Qi Tian

The high performance of denoising diffusion models for image generation has paved the way for their application in unsupervised medical anomaly detection. As diffusion-based methods require a lot of GPU memory and have long sampling times,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Julia Wolleb , Florentin Bieder , Paul Friedrich , Peter Zhang , Alicia Durrer , Philippe C. Cattin

Discrete diffusion models form a powerful class of generative models across diverse domains, including text and graphs. However, existing approaches face fundamental limitations. Masked diffusion models suffer from irreversible errors due…

Machine Learning · Computer Science 2026-04-21 Marcel Kollovieh , Sirine Ayadi , Stephan Günnemann

This review explores anomaly localization in medical images using denoising diffusion models. After providing a brief methodological background of these models, including their application to image reconstruction and their conditioning…

Image and Video Processing · Electrical Eng. & Systems 2025-12-15 Cosmin I. Bercea , Philippe C. Cattin , Julia A. Schnabel , Julia Wolleb

In this work, we propose FastDPM, a unified framework for fast sampling in diffusion probabilistic models. FastDPM generalizes previous methods and gives rise to new algorithms with improved sample quality. We systematically investigate the…

Machine Learning · Computer Science 2021-06-25 Zhifeng Kong , Wei Ping