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Deep learning models have achieved strong performance in medical image analysis, but their internal decision processes remain difficult to interpret. Concept Bottleneck Models (CBMs) partially address this limitation by structuring…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Getamesay Dagnaw , Xuefei Yin , Muhammad Hassan Maqsood , Yanming Zhu , Alan Wee-Chung Liew

In recent years, AI models that mine intrinsic patterns from molecular structures and protein sequences have shown promise in accelerating drug discovery. However, these methods partly lag behind real-world pharmaceutical approaches of…

Machine Learning · Computer Science 2023-10-17 Yizhen Luo , Xing Yi Liu , Kai Yang , Kui Huang , Massimo Hong , Jiahuan Zhang , Yushuai Wu , Zaiqing Nie

It is a common practice in modern medicine to prescribe multiple medications simultaneously to treat diseases. However, these medications could have adverse reactions between them, known as Drug-Drug Interactions (DDI), which have the…

Machine Learning · Computer Science 2024-12-10 Azwad Tamir , Jiann-Shiun Yuan

In the healthcare domain, summarizing medical questions posed by patients is critical for improving doctor-patient interactions and medical decision-making. Although medical data has grown in complexity and quantity, the current body of…

Leveraging datasets available to learn a model with high generalization ability to unseen domains is important for computer vision, especially when the unseen domain's annotated data are unavailable. We study a novel and practical problem…

Computer Vision and Pattern Recognition · Computer Science 2021-04-09 Yang Shu , Zhangjie Cao , Chenyu Wang , Jianmin Wang , Mingsheng Long

Digital health analytics face critical challenges nowadays. The sophisticated analysis of patient-generated health content, which contains complex emotional and medical contexts, requires scarce domain expertise, while traditional ML…

Though convolutional neural networks are widely used in different tasks, lack of generalization capability in the absence of sufficient and representative data is one of the challenges that hinder their practical application. In this paper,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Yufei Wang , Haoliang Li , Lap-pui Chau , Alex C. Kot

With the advancement of telemedicine, both researchers and medical practitioners are working hand-in-hand to develop various techniques to automate various medical operations, such as diagnosis report generation. In this paper, we first…

Computation and Language · Computer Science 2023-09-28 Abhisek Tiwari , Anisha Saha , Sriparna Saha , Pushpak Bhattacharyya , Minakshi Dhar

The increasing reliance on Large Language Models (LLMs) for health information seeking can pose severe risks due to the potential for misinformation and the complexity of these topics. This paper introduces KNOWNET a visualization system…

Human-Computer Interaction · Computer Science 2024-09-27 Youfu Yan , Yu Hou , Yongkang Xiao , Rui Zhang , Qianwen Wang

We propose a unified optimization framework that combines neural networks with dictionary learning to model complex interactions between resting state functional MRI and behavioral data. The dictionary learning objective decomposes patient…

Machine Learning · Computer Science 2024-11-21 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

This paper presents a study on the integration of domain-specific knowledge in prompt engineering to enhance the performance of large language models (LLMs) in scientific domains. A benchmark dataset is curated to encapsulate the intricate…

Computation and Language · Computer Science 2024-04-24 Hongxuan Liu , Haoyu Yin , Zhiyao Luo , Xiaonan Wang

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

The global shortage and uneven distribution of medical expertise continue to hinder equitable access to accurate diagnostic care. While existing intelligent diagnostic system have shown promise, most struggle with dual-user interaction, and…

Human-Computer Interaction · Computer Science 2026-01-29 Zihan Zhou , Yinan Liu , Yuyang Xie , Bin Wang , Xiaochun Yang , Zezheng Feng

While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…

Machine Learning · Computer Science 2024-08-26 Zhihao Yu , Yujie Jin , Yongxin Xu , Xu Chu , Yasha Wang , Junfeng Zhao

Deep learning architectures have an extremely high-capacity for modeling complex data in a wide variety of domains. However, these architectures have been limited in their ability to support complex prediction problems using insurance…

learning algorithms. In this paper, we review the classification algorithms used in the health care system (chronic diseases) and present the neural network-based Ensemble learning method. We briefly describe the commonly used algorithms…

Machine Learning · Computer Science 2021-03-16 Jafar Abdollahi , Babak Nouri-Moghaddam , Mehdi Ghazanfari

The goal of personalized medicine is to discover a treatment regimen that optimizes a patient's clinical outcome based on their personal genetic and environmental factors. However, candidate treatments cannot be arbitrarily administered to…

Machine Learning · Computer Science 2026-02-09 Michael S. Yao , Osbert Bastani , Alma Andersson , Tommaso Biancalani , Aïcha Bentaieb , Claudia Iriondo

The prediction of intrinsic disorder regions has significant implications for understanding protein functions and dynamics. It can help to discover novel protein-protein interactions essential for designing new drugs and enzymes. Recently,…

Machine Learning · Computer Science 2025-08-19 Krzysztof Kotowski , Irena Roterman , Katarzyna Stapor

Background: Image classification can be considered one of the key pillars of medical image analysis. Deep learning (DL) faces challenges that prevent its practical applications despite the remarkable improvement in medical image…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Shahabedin Nabavi , Kian Anvari Hamedani , Mohsen Ebrahimi Moghaddam , Ahmad Ali Abin , Alejandro F. Frangi

The goal of precision medicine is to provide individualized treatment at each stage of chronic diseases, a concept formalized by Dynamic Treatment Regimes (DTR). These regimes adapt treatment strategies based on decision rules learned from…

Methodology · Statistics 2025-06-09 Sophia Yazzourh , Nicolas Savy , Philippe Saint-Pierre , Michael R. Kosorok