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This paper (parts I and II) provides an expository introduction to monotone and near-monotone dynamical systems associated to biochemical networks, those whose graphs are consistent or near-consistent. Many conclusions can be drawn from…

Molecular Networks · Quantitative Biology 2007-05-23 Eduardo D. Sontag

Adaptive transport networks in biological and physical systems exhibit hierarchical organization, characteristic channel spacing, and robust scaling relations. Existing adaptive network models, formulated on a lattice, successfully…

Adaptation and Self-Organizing Systems · Physics 2026-05-18 Sidney Holden , Mia C. Morrell , Geoffrey Vasil , Eleni Katifori

Continuous adaptation allows survival in an ever-changing world. Adjustments in the synaptic coupling strength between neurons are essential for this capability, setting us apart from simpler, hard-wired organisms. How these changes can be…

Neurons and Cognition · Quantitative Biology 2021-01-06 Jakob Jordan , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici

This paper (parts I and II) provides an expository introduction to monotone and near-monotone dynamical systems associated to biochemical networks, those whose graphs are consistent or near-consistent. Many conclusions can be drawn from…

Molecular Networks · Quantitative Biology 2007-05-23 Eduardo D. Sontag

Diverse biological networks exhibit universal features distinguished from those of random networks, calling much attention to their origins and implications. Here we propose a minimal evolution model of Boolean regulatory networks, which…

Molecular Networks · Quantitative Biology 2014-11-26 Deok-Sun Lee

The evolution of leadership in migratory populations depends not only on costs and benefits of leadership investments but also on the opportunities for individuals to rely on cues from others through social interactions. We derive an…

Adaptation and Self-Organizing Systems · Physics 2013-05-17 Darren Pais , Naomi Ehrich Leonard

This study performs parameter inference in a partial differential equations system of pulmonary circulation. We use a fluid dynamics network model that takes selected parameter values and mimics the behaviour of the pulmonary haemodynamics…

Networks are a natural representation of complex systems across the sciences, and higher-order dependencies are central to the understanding and modeling of these systems. However, in many practical applications such as online social…

Social and Information Networks · Computer Science 2020-10-28 Nesreen K. Ahmed , Nick Duffield

In this paper we present a network model to study the impact of spatial distribution of constituents, coupling between them and diffusive processes in the context of biological situations. The model is in terms of network of mobile elements…

Molecular Networks · Quantitative Biology 2007-05-23 Kanchan Thadani , Ashutosh

Time-varying graphs are a useful model for networks with dynamic connectivity such as vehicular networks, yet, despite their great modeling power, many important features of time-varying graphs are still poorly understood. In this paper, we…

Networking and Internet Architecture · Computer Science 2016-01-27 Qingkai Liang , Eytan Modiano

The structure and dynamics of a typical biological system are complex due to strong and inhomogeneous interactions between its constituents. The investigation of such systems with classical mathematical tools, such as differential equations…

Molecular Networks · Quantitative Biology 2008-02-15 Murat Tuğrul

Understanding of vascular organization is a long-standing problem in quantitative biology and biophysics and is essential for the growth of large cultured tissues. Approaches are needed that (1) make predictions of optimal arteriovenous…

Tissues and Organs · Quantitative Biology 2023-08-25 James P. Hague

Co-evolutionary adaptive mechanisms are not only ubiquitous in nature, but also beneficial for the functioning of a variety of systems. We here consider an adaptive network of oscillators with a stochastic, fitness-based, rule of…

Physics and Society · Physics 2016-06-08 Young-Ho Eom , Stefano Boccaletti , Guido Caldarelli

We develop a path-based approach to continuous-time random walks on networks with arbitrarily weighted edges. We describe an efficient numerical algorithm for calculating statistical properties of the stochastic path ensemble. After…

Populations and Evolution · Quantitative Biology 2014-08-19 Michael Manhart , Alexandre V. Morozov

Vascular networks play a key role in the development, function, and survival of many organisms, facilitating transport of nutrients and other critical factors within and between systems. The development of these vessel networks has been…

Tissues and Organs · Quantitative Biology 2022-03-23 Benjamin J. Walker , Adriana T. Dawes

The galactose network is a complex system responsible for galactose metabolism. It has been extensively studied experimentally and mathematically at the unicellular level to broaden our understanding of its regulatory mechanisms at higher…

Molecular Networks · Quantitative Biology 2016-02-12 Tina M. Mitre , Anmar Khadra , Michael C. Mackey

It is a fundamental challenge to understand how the function of a network is related to its structural organization. Adaptive dynamical networks represent a broad class of systems that can change their connectivity over time depending on…

Adaptation and Self-Organizing Systems · Physics 2023-04-13 Rico Berner , Thilo Gross , Christian Kuehn , Jürgen Kurths , Serhiy Yanchuk

The major biochemical networks of the living cell, the network of interacting genes and the network of biochemical reactions, are highly interdependent, however, they have been studied mostly as separate systems so far. In the last years an…

Molecular Networks · Quantitative Biology 2017-11-01 David F. Klosik , Anne Grimbs , Stefan Bornholdt , Marc-Thorsten Hütt

Random graph mixture models are now very popular for modeling real data networks. In these setups, parameter estimation procedures usually rely on variational approximations, either combined with the expectation-maximisation (\textsc{em})…

Statistics Theory · Mathematics 2010-12-09 Christophe Ambroise , Catherine Matias

Mathematical modeling has broad applications in neuroscience whether modeling the dynamics of a single synapse or an entire network of neurons. In Part I, we model vesicle replenishment and release at the photoreceptor synapse to better…

Neurons and Cognition · Quantitative Biology 2017-02-23 Caitlyn M. Parmelee