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This article summarizes a variety of physical mechanisms proposed in the literature, which can generate micro- and nanodomains in multicomponent lipid bilayers and biomembranes. It mainly focusses on lipid-driven mechanisms that do not…

Biological Physics · Physics 2016-11-16 Friederike Schmid

We consider bilayer quantum Hall systems at total filling factor $\nu=1$ in presence of a bias voltage $\Delta_v$ which leads to different filling factors in each layer. We use auxiliary field functional integral approach to study…

Mesoscale and Nanoscale Physics · Physics 2009-11-07 Yogesh N. Joglekar , Allan H. MacDonald

In this perspective, we discuss where and how accounting for electronic many-body polarization affects the accuracy of classical molecular dynamics simulations of biomolecules.While the effects of electronic polarization are highly…

Chemical Physics · Physics 2021-03-29 Josef Melcr , Jean-Philip Piquemal

We develop a theory for describing frictional drag in bilayer systems with in-plane periodic potential modulations, and use it to investigate the drag between bilayer systems in which one of the layers is modulated in one direction. At low…

Mesoscale and Nanoscale Physics · Physics 2009-11-07 Audrius Alkauskas , Karsten Flensberg , Ben Yu-Kuang Hu , Antti-Pekka Jauho

Lipid membranes, the barrier defining living cells and many of their sub-compartments, bind to a wide variety of nano- and micro-meter sized objects. In the presence of strong adhesive forces, membranes can strongly deform and wrap the…

We study the effects of chiral constituent molecules on the macroscopic shapes attained by lipid bilayer membranes. Such fluid membranes are beautiful examples of statistical ensembles of random shapes, sometimes coupled to in-plane order.…

Condensed Matter · Physics 2008-02-03 P. Nelson , T. Powers

Lipid-bilayers are the fundamental constituents of the walls of most living cells and lipid vesicles, giving them shape and compartment. The formation and growing of pores in a lipid bilayer have attracted considerable attention from an…

Soft Condensed Matter · Physics 2015-06-19 Meisam Asgari , Aisa Biria

Understanding how electric fields destabilize biological membranes is important for electroporation-based technologies and bioelectronic interfaces. However, theoretical descriptions of this phenomenon remain fragmented. Existing theories…

Soft Condensed Matter · Physics 2026-03-25 Sirui Ning , Yannick A. D. Omar , Karthik Shekhar , Kranthi K. Mandadapu

Voltage and charge distributions in cellular microdomains regulate communications, excitability, and signal transduction. We report here new electrical laws in a cell, which follow from a nonlinear electro-diffusion model. These newly…

Biological Physics · Physics 2017-01-03 Jerome Cartailler , Zeev Schuss , David Holcman

The organization of lipids in biological membranes is essential for cellular functions such as signal transduction and membrane trafficking. A major challenge is how to control lateral lipid composition in supported membranes which are…

Soft Condensed Matter · Physics 2016-08-31 Qing Liang , Yu-qiang Ma

The ability to control magnetic interactions at the nanoscale is crucial for the development of next-generation spintronic devices and functional magnetic materials. In this work, we investigate theoretically, by means of many-body…

Mesoscale and Nanoscale Physics · Physics 2025-09-18 Tomas T. Osterholt , D. O. Oriekhov , Lumen Eek , Cristiane Morais Smith , Rembert A. Duine

We address the problem of antimicrobial peptides that create pores in lipid bilayers, focusing on voltage-temperature dependence of pore opening. Two novel experiments (voltage-clamp with alamethicin as an emblematic representative of these…

Soft Condensed Matter · Physics 2013-07-17 G. C. Fadda , D. Lairez , Z. Guennouni , A. Koutsioubas

We generalize the predictions for attractions between over-all neutral surfaces induced by charge fluctuations/correlations to non-uniform systems that include dielectric discontinuities, as is the case for mixed charged lipid membranes in…

Soft Condensed Matter · Physics 2009-10-31 Rebecca Menes , Philip Pincus , Bean Stein

We review recent computer simulation studies of undulating lipid bilayers. Theoretical interpretations of such fluctuating membranes are most commonly based on generalized Helfrich-type elastic models, with additional contributions of local…

Biological Physics · Physics 2013-09-03 Friederike Schmid

Conical inclusions in a lipid bilayer generate an overall spontaneous curvature of the membrane that depends on concentration and geometry of the inclusions. Examples are integral and attached membrane proteins, viruses, and lipid domains.…

Soft Condensed Matter · Physics 2009-10-19 Thorsten Auth , Gerhard Gompper

Microphase separation of membrane components is thought to play an important role in many physiological processes, from cell signaling to endocytosis and cellular trafficking. Here, we study how variations in the membrane composition can be…

Subcellular Processes · Quantitative Biology 2015-05-20 Pierre Sens , Matthew S. Turner

Lipid membranes form the barrier between the inside and outside of cells and many of their subcompartments. As such, they bind to a wide variety of nano- and micrometer sized objects and, in the presence of strong adhesive forces, strongly…

Soft Condensed Matter · Physics 2021-08-31 Hendrik T. Spanke , Jaime Agudo-Canalejo , Daniel Tran , Robert W. Style , Eric R. Dufresne

In this paper we present the results of a large-scale numerical investigation of structural properties of a model of cell membrane, simulated as a bilayer of flexible molecules in vacuum. The study was performed by carrying out extensive…

Biological Physics · Physics 2009-11-07 G. La Penna , S. Letardi , V. Minicozzi , S. Morante , G. C. Rossi , G. Salina

In-plane magnetic fields offer a relatively unexplored opportunity to alter the band structure of stacks of 2D materials so that they exhibit desired physical properties. Here we show that an in-plane magnetic field combined with a…

Mesoscale and Nanoscale Physics · Physics 2025-03-17 Amarnath Chakraborty , Aleksandr Rodin , Shaffique Adam , Giovanni Vignale

The light-driven reactions of photosynthesis, as well as the mitochondrial power supply, are hosted within specialized membranes containing a high fraction of redoxactive lipids. Protein mobility and diffusion of redox lipids is believed to…

Biological Physics · Physics 2021-04-19 Ulrich Ramach , Rosmarie Schöfbeck , Jakob Andersson , Markus Valtiner