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Continuous response variables often need to be transformed to meet regression modeling assumptions; however, finding the optimal transformation is challenging and results may vary with the choice of transformation. When a continuous…

Methodology · Statistics 2022-07-19 Yuqi Tian , Bryan E. Shepherd , Chun Li , Donglin Zeng , Jonathan J. Schildcrout

The recent increase in morbidity is primarily due to chronic diseases including Diabetes, Heart disease, Lung cancer, and brain tumours. The results for patients can be improved, and the financial burden on the healthcare system can be…

Machine Learning · Computer Science 2025-02-18 Sri Varsha Mulakala , G. Neeharika , P. Vinay Kumar , A. Bhargava Kiran

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

Machine Learning · Computer Science 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

Recent advances in deep learning algorithms have led to significant benefits for solving many medical image analysis problems. Training deep learning models commonly requires large datasets with expert-labeled annotations. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Stephanie Wichuk , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

A ubiquitous challenge in machine learning is the problem of domain generalisation. This can exacerbate bias against groups or labels that are underrepresented in the datasets used for model development. Model bias can lead to unintended…

The remarkable success of deep learning in recent years has prompted applications in medical image classification and diagnosis tasks. While classification models have demonstrated robustness in classifying simpler datasets like MNIST or…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Sushmita Sarker , Prithul Sarker , George Bebis , Alireza Tavakkoli

Labeled data is a fundamental component in training supervised deep learning models for computer vision tasks. However, the labeling process, especially for ordinal image classification where class boundaries are often ambiguous, is prone…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Alireza Sedighi Moghaddam , Mohammad Reza Mohammadi

Multi-label learning draws great interests in many real world applications. It is a highly costly task to assign many labels by the oracle for one instance. Meanwhile, it is also hard to build a good model without diagnosing discriminative…

Machine Learning · Computer Science 2019-04-16 Bo Du , Zengmao Wang , Lefei Zhang , Liangpei Zhang , Dacheng Tao

Learning from noisy ordinal labels is a key challenge in medical imaging. In this work, we ask whether ordinal disease progression labels (better, worse, or stable) can be used to learn a representation allowing to classify disease state.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Gustav Schmidt , Holger Heidrich , Philipp Berens , Sarah Müller

Healthcare providers usually record detailed notes of the clinical care delivered to each patient for clinical, research, and billing purposes. Due to the unstructured nature of these narratives, providers employ dedicated staff to assign…

Computation and Language · Computer Science 2022-08-03 Chufan Gao , Mononito Goswami , Jieshi Chen , Artur Dubrawski

Uncertainty quantification of causal effects is crucial for safety-critical applications such as personalized medicine. A powerful approach for this is conformal prediction, which has several practical benefits due to model-agnostic…

Machine Learning · Computer Science 2026-02-04 Maresa Schröder , Dennis Frauen , Jonas Schweisthal , Konstantin Heß , Valentyn Melnychuk , Stefan Feuerriegel

Machine learning-based decision support systems are increasingly deployed in clinical settings, where probabilistic scoring functions are used to inform and prioritize patient management decisions. However, widely used scoring rules, such…

Machine Learning · Computer Science 2025-07-01 Gerardo A. Flores , Alyssa H. Smith , Julia A. Fukuyama , Ashia C. Wilson

Since most machine learning (ML) algorithms are designed for numerical inputs, efficiently encoding categorical variables is a crucial aspect in data analysis. A common problem are high cardinality features, i.e. unordered categorical…

Machine Learning · Statistics 2022-03-07 Florian Pargent , Florian Pfisterer , Janek Thomas , Bernd Bischl

This paper proposes a deep convolutional neural network model for ordinal regression by considering a family of probabilistic ordinal link functions in the output layer. The link functions are those used for cumulative link models, which…

Computer Vision and Pattern Recognition · Computer Science 2019-10-11 Víctor-Manuel Vargas , Pedro-Antonio Gutiérrez , César Hervás-Martínez

Prediction models for clinical outcomes may be developed using a source dataset and additionally applied to new settings. Towards model external validation and model updating in the new setting, one procedure is model modification learning…

Methodology · Statistics 2020-12-01 W Katherine Tan , Patrick J Heagerty

As the significance of understanding the cause-and-effect relationships among variables increases in the development of modern systems and algorithms, learning causality from observational data has become a preferred and efficient approach…

Machine Learning · Computer Science 2024-11-28 Xiaoxuan Li , Yao Liu , Ruoyu Wang , Lina Yao

The degree to which subjects differ from each other with respect to certain properties measured by a set of variables, plays an important role in many statistical methods. For example, classification, clustering, and data visualization…

Machine Learning · Statistics 2023-01-06 Michel van de Velden , Alfonso Iodice D'Enza , Angelos Markos , Carlo Cavicchia

In clinical practice, decision-making relies heavily on established protocols, often formalised as rules. Concurrently, Machine Learning (ML) models, trained on clinical data, aspire to integrate into medical decision-making processes.…

Artificial Intelligence · Computer Science 2024-11-06 Christel Sirocchi , Muhammad Suffian , Federico Sabbatini , Alessandro Bogliolo , Sara Montagna

Generalization is an important attribute of machine learning models, particularly for those that are to be deployed in a medical context, where unreliable predictions can have real world consequences. While the failure of models to…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Brennan Nichyporuk , Jillian Cardinell , Justin Szeto , Raghav Mehta , Jean-Pierre R. Falet , Douglas L. Arnold , Sotirios A. Tsaftaris , Tal Arbel

The integration of artificial intelligence into clinical workflows requires reliable and robust models. Among the main features of robustness is repeatability. Much attention is given to classification performance without assessing the…