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Electroencephalography (EEG) is a widely used, non-invasive method for capturing brain activity, and is particularly relevant for applications in Brain-Computer Interfaces (BCI). However, collecting high-quality EEG data remains a major…

Signal Processing · Electrical Eng. & Systems 2025-10-22 Henrique de Lima Alexandre , Clodoaldo Aparecido de Moraes Lima

This paper presents a novel approach to simulating electronic health records (EHRs) using diffusion probabilistic models (DPMs). Specifically, we demonstrate the effectiveness of DPMs in synthesising longitudinal EHRs that capture…

Machine Learning · Computer Science 2023-03-23 Nicholas I-Hsien Kuo , Louisa Jorm , Sebastiano Barbieri

In this paper, we investigate the use of diffusion models which are pre-trained on large-scale image-caption pairs for open-vocabulary 3D semantic understanding. We propose a novel method, namely Diff2Scene, which leverages frozen…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Xiaoyu Zhu , Hao Zhou , Pengfei Xing , Long Zhao , Hao Xu , Junwei Liang , Alexander Hauptmann , Ting Liu , Andrew Gallagher

The lack of real-world data in clinical fields poses a major obstacle in training effective AI models for diagnostic and preventive tools in medicine. Generative AI has shown promise in increasing data volume and enhancing model training,…

Machine Learning · Computer Science 2026-02-10 Md Shahriar Kabir , Sana Alamgeer , Minakshi Debnath , Anne H. H. Ngu

Diffusion probabilistic models (DPMs) have achieved remarkable quality in image generation that rivals GANs'. But unlike GANs, DPMs use a set of latent variables that lack semantic meaning and cannot serve as a useful representation for…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 Konpat Preechakul , Nattanat Chatthee , Suttisak Wizadwongsa , Supasorn Suwajanakorn

The generation of realistic medical images from text descriptions has significant potential to address data scarcity challenges in healthcare AI while preserving patient privacy. This paper presents a comprehensive study of text-to-image…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Mikhail Chaichuk , Sushant Gautam , Steven Hicks , Elena Tutubalina

Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

This study aims to develop a novel Cycle-guided Denoising Diffusion Probability Model (CG-DDPM) for cross-modality MRI synthesis. The CG-DDPM deploys two DDPMs that condition each other to generate synthetic images from two different MRI…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Shaoyan Pan , Chih-Wei Chang , Junbo Peng , Jiahan Zhang , Richard L. J. Qiu , Tonghe Wang , Justin Roper , Tian Liu , Hui Mao , Xiaofeng Yang

Advancements in AI for medical imaging offer significant potential. However, their applications are constrained by the limited availability of data and the reluctance of medical centers to share it due to patient privacy concerns.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Marvin Seyfarth , Salman Ul Hassan Dar , Isabelle Ayx , Matthias Alexander Fink , Stefan O. Schoenberg , Hans-Ulrich Kauczor , Sandy Engelhardt

3D brain MRI studies often examine subtle morphometric differences between cohorts that are hard to detect visually. Given the high cost of MRI acquisition, these studies could greatly benefit from image syntheses, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Binxu Li , Wei Peng , Mingjie Li , Ehsan Adeli , Kilian M. Pohl

Denoising Diffusion Probabilistic Models (DDPMs) have made great strides in generating high-quality samples in both discrete and continuous domains. However, Discrete DDPMs (D3PMs) have yet to be applied to the domain of Symbolic Music.…

Sound · Computer Science 2023-05-17 Matthias Plasser , Silvan Peter , Gerhard Widmer

Due to the three-dimensional nature of CT- or MR-scans, generative modeling of medical images is a particularly challenging task. Existing approaches mostly apply patch-wise, slice-wise, or cascaded generation techniques to fit the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Paul Friedrich , Julia Wolleb , Florentin Bieder , Alicia Durrer , Philippe C. Cattin

Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines. While deep generative models have shown promise in inpainting these lesions, most existing methods operate…

Image and Video Processing · Electrical Eng. & Systems 2026-03-09 Zahra Karimaghaloo , Dumitru Fetco , Haz-Edine Assemlal , Hassan Rivaz , Douglas L. Arnold

This paper introduces a methodology for generating synthetic annotated data to address data scarcity in semantic segmentation tasks within the precision agriculture domain. Utilizing Denoising Diffusion Probabilistic Models (DDPMs) and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-07 Andrew Heschl , Mauricio Murillo , Keyhan Najafian , Farhad Maleki

Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Md Selim , Jie Zhang , Faraneh Fathi , Michael A. Brooks , Ge Wang , Guoqiang Yu , Jin Chen

Despite the increasing use of deep learning in medical image segmentation, the limited availability of annotated training data remains a major challenge due to the time-consuming data acquisition and privacy regulations. In the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

The advance of generative models for images has inspired various training techniques for image recognition utilizing synthetic images. In semantic segmentation, one promising approach is extracting pseudo-masks from attention maps in…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Ryota Yoshihashi , Yuya Otsuka , Kenji Doi , Tomohiro Tanaka , Hirokatsu Kataoka

Solving medical imaging data scarcity through semantic image generation has attracted growing attention in recent years. However, existing generative models mainly focus on synthesizing whole-organ or large-tissue structures, showing…

Image and Video Processing · Electrical Eng. & Systems 2025-12-19 Jiahao Xia , Yutao Hu , Yaolei Qi , Zhenliang Li , Wenqi Shao , Junjun He , Ying Fu , Longjiang Zhang , Guanyu Yang

Denoising Diffusion Probabilistic Model (DDPM) is able to make flexible conditional image generation from prior noise to real data, by introducing an independent noise-aware classifier to provide conditional gradient guidance at each time…

Computer Vision and Pattern Recognition · Computer Science 2022-09-21 Shengming Li , Guangcong Zheng , Hui Wang , Taiping Yao , Yang Chen , Shoudong Ding , Xi Li

Automated cell segmentation in microscopy images is essential for biomedical research, yet conventional methods are labor-intensive and prone to error. While deep learning-based approaches have proven effective, they often require large…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Rüveyda Yilmaz , Kaan Keven , Yuli Wu , Johannes Stegmaier