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The ability to perform causal reasoning is widely considered a core feature of intelligence. In this work, we investigate whether large language models (LLMs) can coherently reason about causality. Much of the existing work in natural…

Accurate breast lesion risk estimation can significantly reduce unnecessary biopsies and help doctors decide optimal treatment plans. Most existing computer-aided systems rely solely on mammogram features to classify breast lesions. While…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Hung Q. Vo , Pengyu Yuan , Tiancheng He , Stephen T. C. Wong , Hien V. Nguyen

Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests…

Machine Learning · Computer Science 2019-08-20 Sterling Ramroach , Melford John , Ajay Joshi

As the significance of understanding the cause-and-effect relationships among variables increases in the development of modern systems and algorithms, learning causality from observational data has become a preferred and efficient approach…

Machine Learning · Computer Science 2024-11-28 Xiaoxuan Li , Yao Liu , Ruoyu Wang , Lina Yao

Breast cancer is one of the leading causes of cancer deaths in women. As the primary output of breast screening, breast ultrasound (US) video contains exclusive dynamic information for cancer diagnosis. However, training models for video…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Zehui Lin , Ruobing Huang , Dong Ni , Jiayi Wu , Baoming Luo

Beneficial to advanced computing devices, models with massive parameters are increasingly employed to extract more information to enhance the precision in describing and predicting the patterns of objective systems. This phenomenon is…

Information Theory · Computer Science 2024-03-08 Liye Jia , Fengyufan Yang , Ka Lok Man , Erick Purwanto , Sheng-Uei Guan , Jeremy Smith , Yutao Yue

Faithful evaluation of language model capabilities is crucial for deriving actionable insights that can inform model development. However, rigorous causal evaluations in this domain face significant methodological challenges, including…

Machine Learning · Computer Science 2025-06-13 Jikai Jin , Vasilis Syrgkanis , Sham Kakade , Hanlin Zhang

As machine learning models become increasingly integrated into healthcare, structural inequities and social biases embedded in clinical data can be perpetuated or even amplified by data-driven models. In survival analysis, censoring and…

Genomics are rapidly transforming medical practice and basic biomedical research, providing insights into disease mechanisms and improving therapeutic strategies, particularly in cancer. The ability to predict the future course of a…

Neural and Evolutionary Computing · Computer Science 2016-09-29 Safoora Yousefi , Congzheng Song , Nelson Nauata , Lee Cooper

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

Computation and Language · Computer Science 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

Causal structure discovery methods are commonly applied to structured data where the causal variables are known and where statistical testing can be used to assess the causal relationships. By contrast, recovering a causal structure from…

Computation and Language · Computer Science 2024-10-10 Gaël Gendron , Jože M. Rožanec , Michael Witbrock , Gillian Dobbie

We conducted an exploratory study in virtual reality to examine if people can discover causal relations in a realistic sensorimotor context and how such learning is represented at different processing levels (conscious-cognitive vs.…

Human-Computer Interaction · Computer Science 2026-01-15 Nikolai Bahr , Christoph Zetzsche , Jaime Maldonado , Kerstin Schill

Causality understanding between events is a critical natural language processing task that is helpful in many areas, including health care, business risk management and finance. On close examination, one can find a huge amount of textual…

Computation and Language · Computer Science 2021-02-01 Vivek Khetan , Roshni Ramnani , Mayuresh Anand , Shubhashis Sengupta , Andrew E. Fano

Methods of causal discovery aim to identify causal structures in a data driven way. Existing algorithms are known to be unstable and sensitive to statistical errors, and are therefore rarely used with biomedical or epidemiological data. We…

Methodology · Statistics 2024-07-01 Christine W Bang , Janine Witte , Ronja Foraita , Vanessa Didelez

It is imperative that breast cancer is detected precisely and timely to improve patient outcomes. Diagnostic methodologies have traditionally relied on unimodal approaches; however, medical data analytics is integrating diverse data sources…

Machine Learning · Computer Science 2024-06-21 Faseela Abdullakutty , Younes Akbari , Somaya Al-Maadeed , Ahmed Bouridane , Rifat Hamoudi

Background: Accurate survival prediction in breast cancer is essential for patient stratification and personalized therapy. Integrating gene expression data with clinical factors may enhance prognostic performance and support precision…

Quantitative Methods · Quantitative Biology 2025-08-26 Robert Amevor , Emmanuel Kubuafor , Dennis Baidoo , Junaidu Salifu , Koshali Muthunama Gonnage , Onyedikachi Joshua Okeke

While witnessing the exceptional success of machine learning (ML) technologies in many applications, users are starting to notice a critical shortcoming of ML: correlation is a poor substitute for causation. The conventional way to discover…

Machine Learning · Computer Science 2024-09-26 Ahmet Kapkiç , Pratanu Mandal , Shu Wan , Paras Sheth , Abhinav Gorantla , Yoonhyuk Choi , Huan Liu , K. Selçuk Candan

The development of high-throughput sequencing and targeted therapies has led to the emergence of personalized medicine: a patient's molecular profile or the presence of a specific biomarker of drug response will correspond to a treatment…

Applications · Statistics 2020-05-27 Jonas Béal , Aurélien Latouche

Many benchmarks for automated causal inference evaluate a system's performance based on a single numerical output, such as an Average Treatment Effect (ATE). This approach conflates two distinct steps in causal analysis: identification -…

Artificial Intelligence · Computer Science 2026-05-15 Ayush Sawarni , Jiyuan Tan , Vasilis Syrgkanis

Aligning the decision-making process of machine learning algorithms with that of experienced radiologists is crucial for reliable diagnosis. While existing methods have attempted to align their diagnosis behaviors to those of radiologists…

Machine Learning · Computer Science 2025-02-10 Mingzhou Liu , Ching-Wen Lee , Xinwei Sun , Yu Qiao , Yizhou Wang
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