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Recommendation algorithms have been pivotal in handling the overwhelming volume of online content. However, these algorithms seldom consider direct user input, resulting in superficial interaction between them. Efforts have been made to…

Information Retrieval · Computer Science 2024-01-09 Kyle Dylan Spurlock , Cagla Acun , Esin Saka , Olfa Nasraoui

Large language model (LLM) applications, such as ChatGPT, are a powerful tool for online information-seeking (IS) and problem-solving tasks. However, users still face challenges initializing and refining prompts, and their cognitive…

Human-Computer Interaction · Computer Science 2024-02-12 Ben Wang , Jiqun Liu , Jamshed Karimnazarov , Nicolas Thompson

Protein research is crucial in various fundamental disciplines, but understanding their intricate structure-function relationships remains challenging. Recent Large Language Models (LLMs) have made significant strides in comprehending…

Computational Engineering, Finance, and Science · Computer Science 2025-01-24 Chao Wang , Hehe Fan , Ruijie Quan , Yi Yang

In the rapidly evolving field of business process management, there is a growing need for analytical tools that can transform complex data into actionable insights. This research introduces a novel approach by integrating Large Language…

Computation and Language · Computer Science 2024-05-20 Mehrdad Agha Mohammad Ali Kermani , Hamid Reza Seddighi , Mehrdad Maghsoudi

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

Text summarization has been a crucial problem in natural language processing (NLP) for several decades. It aims to condense lengthy documents into shorter versions while retaining the most critical information. Various methods have been…

Computation and Language · Computer Science 2023-02-17 Xianjun Yang , Yan Li , Xinlu Zhang , Haifeng Chen , Wei Cheng

The recent progress of large language models (LLMs), including ChatGPT and GPT-4, in comprehending and responding to human instructions has been remarkable. Nevertheless, these models typically perform better in English and have not been…

Computation and Language · Computer Science 2023-04-18 Honglin Xiong , Sheng Wang , Yitao Zhu , Zihao Zhao , Yuxiao Liu , Linlin Huang , Qian Wang , Dinggang Shen

Patients with schizophrenia often present with cognitive impairments that may hinder their ability to learn about their condition. These individuals could benefit greatly from education platforms that leverage the adaptability of Large…

Computation and Language · Computer Science 2024-10-18 Per Niklas Waaler , Musarrat Hussain , Igor Molchanov , Lars Ailo Bongo , Brita Elvevåg

Large Language Models (LLMs), such as ChatGPT, have recently been applied to various NLP tasks due to its open-domain generation capabilities. However, there are two issues with applying LLMs to dialogue tasks. 1. During the dialogue…

Computation and Language · Computer Science 2023-10-06 Siwei Wu , Xiangqing Shen , Rui Xia

While modern dialogue systems heavily rely on large language models (LLMs), their implementation often goes beyond pure LLM interaction. Developers integrate multiple LLMs, external tools, and databases. Therefore, assessment of the…

Artificial Intelligence · Computer Science 2025-07-23 Roman Mayr , Michel Schimpf , Thomas Bohné

Retrosynthesis analysis is pivotal yet challenging in drug discovery and organic chemistry. Despite the proliferation of computational tools over the past decade, AI-based systems often fall short in generalizing across diverse reaction…

Machine Learning · Computer Science 2024-08-21 Yifei Yang , Runhan Shi , Zuchao Li , Shu Jiang , Bao-Liang Lu , Yang Yang , Hai Zhao

Large Language Models (LLMs) have demonstrated remarkable zero-shot generalization across various language-related tasks, including search engines. However, existing work utilizes the generative ability of LLMs for Information Retrieval…

Computation and Language · Computer Science 2024-12-31 Weiwei Sun , Lingyong Yan , Xinyu Ma , Shuaiqiang Wang , Pengjie Ren , Zhumin Chen , Dawei Yin , Zhaochun Ren

The recent success of large language models (LLMs) has shown great potential to develop more powerful conversational recommender systems (CRSs), which rely on natural language conversations to satisfy user needs. In this paper, we embark on…

Computation and Language · Computer Science 2024-06-21 Xiaolei Wang , Xinyu Tang , Wayne Xin Zhao , Jingyuan Wang , Ji-Rong Wen

Finetuning a Large Language Model (LLM) is crucial for generating results towards specific objectives. This research delves into the realm of drug optimization and introduce a novel reinforcement learning algorithm to finetune a drug…

Machine Learning · Computer Science 2025-02-12 Xuefeng Liu , Songhao Jiang , Siyu Chen , Zhuoran Yang , Yuxin Chen , Ian Foster , Rick Stevens

Repurposing approved drugs offers a time-efficient and cost-effective alternative to traditional drug development. However, in silico prediction of repurposing candidates is challenging and requires the effective collaboration of…

Artificial Intelligence · Computer Science 2026-02-10 Simon Süwer , Kester Bagemihl , Sylvie Baier , Lucia Dicunta , Markus List , Jan Baumbach , Andreas Maier , Fernando M. Delgado-Chaves

Drug side effects are a major global health concern, necessitating advanced methods for their accurate detection and analysis. While Large Language Models (LLMs) offer promising conversational interfaces, their inherent limitations,…

Information Retrieval · Computer Science 2025-07-21 Shad Nygren , Pinar Avci , Andre Daniels , Reza Rassol , Afshin Beheshti , Diego Galeano

Molecule discovery plays a crucial role in various scientific fields, advancing the design of tailored materials and drugs. However, most of the existing methods heavily rely on domain experts, require excessive computational cost, or…

Computation and Language · Computer Science 2024-05-10 Jiatong Li , Yunqing Liu , Wenqi Fan , Xiao-Yong Wei , Hui Liu , Jiliang Tang , Qing Li

Large language models (LLMs) like ChatGPT are increasingly used in academic writing, yet issues such as incorrect or fabricated references raise ethical concerns. Moreover, current content quality evaluations often rely on subjective human…

Computation and Language · Computer Science 2025-09-15 Jing Ren , Weiqi Wang

ChatGPT has revolutionized many research and industrial fields. ChatGPT has shown great potential in software engineering to boost various traditional tasks such as program repair, code understanding, and code generation. However, whether…

Software Engineering · Computer Science 2023-04-18 Jialun Cao , Meiziniu Li , Ming Wen , Shing-chi Cheung

Large Language Models (LLMs) like ChatGPT have demonstrated amazing capabilities in comprehending user intents and generate reasonable and useful responses. Beside their ability to chat, their capabilities in various natural language…

Computation and Language · Computer Science 2026-02-12 Liz Li , Wei Zhu
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