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Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

Current recommendation systems recommend goods by considering users' historical behaviors, social relations, ratings, and other multi-modals. Although outdated user information presents the trends of a user's interests, no recommendation…

Information Retrieval · Computer Science 2025-01-07 Jinkun Han , Wei Li , Yingshu Li , Zhipeng Cai

Knowledge tracing (KT) which aims at predicting learner's knowledge mastery plays an important role in the computer-aided educational system. In recent years, many deep learning models have been applied to tackle the KT task, which have…

Computers and Society · Computer Science 2022-08-30 Hanshuang Tong , Zhen Wang , Yun Zhou , Shiwei Tong , Wenyuan Han , Qi Liu

It is a common practice in modern medicine to prescribe multiple medications simultaneously to treat diseases. However, these medications could have adverse reactions between them, known as Drug-Drug Interactions (DDI), which have the…

Machine Learning · Computer Science 2024-12-10 Azwad Tamir , Jiann-Shiun Yuan

Sequential recommendation (SR) aims to predict a user's next action by learning from their historical interaction sequences. In real-world applications, these models require periodic updates to adapt to new interactions and evolving user…

Information Retrieval · Computer Science 2026-02-12 Xiaomeng Song , Xinru Wang , Hanbing Wang , Hongyu Lu , Yu Chen , Zhaochun Ren , Zhumin Chen

Cardiovascular disease is a large worldwide healthcare issue; symptoms often present suddenly with minimal warning. The electrocardiogram (ECG) is a fast, simple and reliable method of evaluating the health of the heart, by measuring…

Signal Processing · Electrical Eng. & Systems 2022-01-15 Yola Jones , Fani Deligianni , Jeff Dalton

Modeling user sequential behaviors has recently attracted increasing attention in the recommendation domain. Existing methods mostly assume coherent preference in the same sequence. However, user personalities are volatile and easily…

Information Retrieval · Computer Science 2022-04-01 Weiqi Shao , Xu Chen , Long Xia , Jiashu Zhao , Dawei Yin

More and more diseases have been found to be strongly correlated with disturbances in the microbiome constitution, e.g., obesity, diabetes, or some cancer types. Thanks to modern high-throughput omics technologies, it becomes possible to…

Quantitative Methods · Quantitative Biology 2021-04-06 Kateryna Melnyk , Stefan Klus , Grégoire Montavon , Tim Conrad

Electronic medical records contain multi-format electronic medical data that consist of an abundance of medical knowledge. Facing with patient's symptoms, experienced caregivers make right medical decisions based on their professional…

Databases · Computer Science 2017-07-25 Meng Wang , Jiaheng Zhang , Jun Liu , Wei Hu , Sen Wang , Xue Li , Wenqiang Liu

Traditional recommendation systems estimate user preference on items from past interaction history, thus suffering from the limitations of obtaining fine-grained and dynamic user preference. Conversational recommendation system (CRS) brings…

Information Retrieval · Computer Science 2020-07-02 Wenqiang Lei , Gangyi Zhang , Xiangnan He , Yisong Miao , Xiang Wang , Liang Chen , Tat-Seng Chua

Knowledge Graphs (KG) constitute a flexible representation of complex relationships between entities particularly useful for biomedical data. These KG, however, are very sparse with many missing edges (facts) and the visualisation of the…

Artificial Intelligence · Computer Science 2016-12-08 Armando Vieira

The wealth of computerised medical information becoming readily available presents the opportunity to examine patterns of illnesses, therapies and responses. These patterns may be able to predict illnesses that a patient is likely to…

Machine Learning · Computer Science 2013-07-05 Jenna Reps , Jonathan M. Garibaldi , Uwe Aickelin , Daniele Soria , Jack E. Gibson , Richard B. Hubbard

Molecular relational learning, whose goal is to learn the interaction behavior between molecular pairs, got a surge of interest in molecular sciences due to its wide range of applications. Recently, graph neural networks have recently shown…

Molecular Networks · Quantitative Biology 2023-07-11 Namkyeong Lee , Dongmin Hyun , Gyoung S. Na , Sungwon Kim , Junseok Lee , Chanyoung Park

Integrative analysis of multi-level pharmacogenomic data for modeling dependencies across various biological domains is crucial for developing genomic-testing based treatments. Chain graphs characterize conditional dependence structures of…

Repeat consumption, such as repurchasing items and relistening songs, is a common scenario in daily life. To model repeat consumption, the repeat-aware recommendation has been proposed to predict which item will be re-interacted based on…

Information Retrieval · Computer Science 2025-06-11 Shigang Quan , Shui Liu , Zhenzhe Zheng , Fan Wu

Attribute recognition has become crucial because of its wide applications in many computer vision tasks, such as person re-identification. Like many object recognition problems, variations in viewpoints, illumination, and recognition at far…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Hao Liu , Jingjing Wu , Jianguo Jiang , Meibin Qi , Bo Ren

Designing a new clinical trial entails many decisions, such as defining a cohort and setting the study objectives to name a few, and therefore can benefit from recommendations based on exhaustive mining of past clinical trial records. Here,…

Artificial Intelligence · Computer Science 2023-09-29 Murthy V. Devarakonda , Smita Mohanty , Raja Rao Sunkishala , Nag Mallampalli , Xiong Liu

Recently, recommendation according to sequential user behaviors has shown promising results in many application scenarios. Generally speaking, real-world sequential user behaviors usually reflect a hybrid of sequential influences and…

Information Retrieval · Computer Science 2019-10-18 Xu Chen , Kenan Cui , Ya Zhang , Yanfeng Wang

Clinical event sequences consist of hundreds of clinical events that represent records of patient care in time. Developing accurate predictive models of such sequences is of a great importance for supporting a variety of models for…

Machine Learning · Computer Science 2023-08-23 Jeong Min Lee , Milos Hauskrecht

Temporal graph learning is pivotal for deciphering dynamic systems, where the core challenge lies in explicitly modeling the underlying evolving patterns that govern network transformation. However, prevailing methods are predominantly…

Machine Learning · Computer Science 2026-02-20 Yijun Ma , Zehong Wang , Weixiang Sun , Yanfang Ye