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Radiologists in their daily work routinely find and annotate significant abnormalities on a large number of radiology images. Such abnormalities, or lesions, have collected over years and stored in hospitals' picture archiving and…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Ke Yan , Xiaosong Wang , Le Lu , Ling Zhang , Adam Harrison , Mohammadhad Bagheri , Ronald Summers

Acquiring large-scale medical image data, necessary for training machine learning algorithms, is frequently intractable, due to prohibitive expert-driven annotation costs. Recent datasets extracted from hospital archives, e.g., DeepLesion,…

Computer Vision and Pattern Recognition · Computer Science 2020-11-24 Jinzheng Cai , Adam P. Harrison , Youjing Zheng , Ke Yan , Yuankai Huo , Jing Xiao , Lin Yang , Le Lu

Monitoring the progression of lesions is important for clinical response. Summary statistics such as lesion volume are objective and easy to interpret, which can help clinicians assess lesion growth or decay. CNNs are commonly used in…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Kevin Raina

We present a novel approach for training deep neural networks in a Bayesian way. Classical, i.e. non-Bayesian, deep learning has two major drawbacks both originating from the fact that network parameters are considered to be deterministic.…

Machine Learning · Statistics 2019-03-11 Konstantin Posch , Jan Steinbrener , Jürgen Pilz

Purpose: In diffusion MRI (dMRI), the volumetric and bundle analyses of whole-brain tissue microstructure and connectivity can be severely impeded by an incomplete field-of-view (FOV). This work aims to develop a method for imputing the…

With the growing interest in foundation models for brain signals, graph-based pretraining has emerged as a promising paradigm for learning transferable representations from connectome data. However, existing contrastive and masked…

Machine Learning · Computer Science 2026-03-10 Xinxu Wei , Rong Zhou , Lifang He , Yu Zhang

Variational mean field approximations tend to struggle with contemporary overparametrized deep neural networks. Where a Bayesian treatment is usually associated with high-quality predictions and uncertainties, the practical reality has been…

Inverse problems and, in particular, inferring unknown or latent parameters from data are ubiquitous in engineering simulations. A predominant viewpoint in identifying unknown parameters is Bayesian inference where both prior information…

Computation · Statistics 2022-08-31 Vahid Keshavarzzadeh , Robert M. Kirby , Akil Narayan

Deep learning fostered a leap ahead in automated skin lesion analysis in the last two years. Those models are expensive to train and difficult to parameterize. Objective: We investigate methodological issues for designing and evaluating…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Eduardo Valle , Michel Fornaciali , Afonso Menegola , Julia Tavares , Flávia Vasques Bittencourt , Lin Tzy Li , Sandra Avila

Diffusion probabilistic models (DPMs) have exhibited significant effectiveness in computer vision tasks, particularly in image generation. However, their notable performance heavily relies on labelled datasets, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Keqiang Fan , Xiaohao Cai , Mahesan Niranjan

A fundamental issue in causal inference for Big Observational Data is confounding due to covariate imbalances between treatment groups. This can be addressed by designing the data prior to analysis. Existing design methods, developed for…

Methodology · Statistics 2022-03-17 Yumin Zhang , Arman Sabbaghi

We propose a recurrent neural network for a "model-free" simulation of a dynamical system with unknown parameters without prior knowledge. The deep learning model aims to jointly learn the nonlinear time marching operator and the effects of…

Machine Learning · Computer Science 2021-03-01 Kyongmin Yeo , Dylan E. C. Grullon , Fan-Keng Sun , Duane S. Boning , Jayant R. Kalagnanam

Dynamic Causal Modeling (DCM) is a Bayesian framework for inferring on hidden (latent) neuronal states, based on measurements of brain activity. Since its introduction in 2003 for functional magnetic resonance imaging data, DCM has been…

Quantitative Methods · Quantitative Biology 2021-04-08 Inês Pereira , Stefan Frässle , Jakob Heinzle , Dario Schöbi , Cao Tri Do , Moritz Gruber , Klaas E. Stephan

Diffusion and flow-based generative models have achieved remarkable success in domains such as image synthesis, video generation, and natural language modeling. In this work, we extend these advances to weight space learning by leveraging…

Machine Learning · Computer Science 2025-10-17 Daniel Saragih , Deyu Cao , Tejas Balaji

Deep neural networks have shown their profound impact on achieving human level performance in visual saliency prediction. However, it is still unclear how they learn the task and what it means in terms of understanding human visual system.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Sai Phani Kumar Malladi , Jayanta Mukhopadhyay , Chaker Larabi , Santanu Chaudhury

Real-world settings often do not allow acquisition of high-resolution volumetric images for accurate morphological assessment and diagnostic. In clinical practice it is frequently common to acquire only sparse data (e.g. individual slices)…

Image and Video Processing · Electrical Eng. & Systems 2019-08-30 Benjamin Hou , Athanasios Vlontzos , Amir Alansary , Daniel Rueckert , Bernhard Kainz

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Learned image reconstruction techniques using deep neural networks have recently gained popularity, and have delivered promising empirical results. However, most approaches focus on one single recovery for each observation, and thus neglect…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Chen Zhang , Riccardo Barbano , Bangti Jin

We present a method to estimate a multivariate Gaussian distribution of diffusion tensor features in a set of brain regions based on a small sample of healthy individuals, and use this distribution to identify imaging abnormalities in…

Applications · Statistics 2017-04-24 Matineh Shaker , Deniz Erdogmus , Jennifer Dy , Sylvain Bouix

Deep neural networks have revolutionized medical image analysis and disease diagnosis. Despite their impressive performance, it is difficult to generate well-calibrated probabilistic outputs for such networks, which makes them…

Machine Learning · Computer Science 2020-05-29 Pranav Poduval , Hrushikesh Loya , Amit Sethi