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We propose generative neural network methods to generate DNA sequences and tune them to have desired properties. We present three approaches: creating synthetic DNA sequences using a generative adversarial network; a DNA-based variant of…

Machine Learning · Computer Science 2017-12-19 Nathan Killoran , Leo J. Lee , Andrew Delong , David Duvenaud , Brendan J. Frey

Inverse design optimization aims to infer system parameters from observed solutions, posing critical challenges across domains such as semiconductor manufacturing, structural engineering, materials science, and fluid dynamics. The lack of…

Artificial Intelligence · Computer Science 2025-10-16 Haoyu Yang , Kamyar Azizzadenesheli , Haoxing Ren

In modern collider experiments, the quest to explore fundamental interactions between elementary particles has reached unparalleled levels of precision. Signatures from particle physics detectors are low-level objects (such as energy…

Instrumentation and Detectors · Physics 2024-07-16 Baran Hashemi , Claudius Krause

Deep neural networks have developed rapidly and have achieved outstanding performance in several tasks, such as image classification and natural language processing. However, recent studies have indicated that both digital and physical…

Cryptography and Security · Computer Science 2021-09-09 Chang-Sheng Lin , Chia-Yi Hsu , Pin-Yu Chen , Chia-Mu Yu

Optimization and uncertainty quantification have been playing an increasingly important role in computational hemodynamics. However, existing methods based on principled modeling and classic numerical techniques have faced significant…

Medical Physics · Physics 2022-09-07 Pan Du , Xiaozhi Zhu , Jian-Xun Wang

Layout designs are encountered in a variety of fields. For problems with many design degrees of freedom, efficiency of design methods becomes a major concern. In recent years, machine learning methods such as artificial neural networks have…

Machine Learning · Computer Science 2021-02-01 Chao Qian , Renkai Tan , Wenjing Ye

We extensively study how to combine Generative Adversarial Networks and learned compression to obtain a state-of-the-art generative lossy compression system. In particular, we investigate normalization layers, generator and discriminator…

Image and Video Processing · Electrical Eng. & Systems 2020-10-26 Fabian Mentzer , George Toderici , Michael Tschannen , Eirikur Agustsson

Transfer learning has gained significant attention in recent deep learning research due to its ability to accelerate convergence and enhance performance on new tasks. However, its success is often contingent on the similarity between source…

Machine Learning · Computer Science 2024-10-28 Bedionita Soro , Bruno Andreis , Hayeon Lee , Wonyong Jeong , Song Chong , Frank Hutter , Sung Ju Hwang

The ability to simulate realistic networks based on empirical data is an important task across scientific disciplines, from epidemiology to computer science. Often simulation approaches involve selecting a suitable network generative model…

Social and Information Networks · Computer Science 2024-06-13 Raima Carol Appaw , Nicholas Fountain-Jones , Michael A. Charleston

We present a detailed description of a new hadronic multiparticle production model for use in neutrino interaction simulations. Its validity spans a wide invariant mass range starting from pion production threshold. This model focuses on…

High Energy Physics - Phenomenology · Physics 2009-11-19 T. Yang , C. Andreopoulos , H. Gallagher , K. Hoffmann , P. Kehayias

Understanding hadronic interactions at high energies represents a very important ingredient for modeling high energy cosmic ray air showers. In this paper, we present a new approach to simulate hadronic interactions, including…

High Energy Physics - Phenomenology · Physics 2007-05-23 H. J. Drescher , M. Hladik , S. Ostapchenko , K. Werner

Deep generative models (DGMs) have the potential to revolutionize diagnostic imaging. Generative adversarial networks (GANs) are one kind of DGM which are widely employed. The overarching problem with deploying GANs, and other DGMs, in any…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Rucha Deshpande , Mark A. Anastasio , Frank J. Brooks

The development of a reliable and robust surrogate model is often constrained by the dimensionality of the problem. For a system with high-dimensional inputs/outputs (I/O), conventional approaches usually use a low-dimensional manifold to…

Image and Video Processing · Electrical Eng. & Systems 2020-10-01 Xihaier Luo , Ahsan Kareem

Deep learning's success has led to larger and larger models to handle more and more complex tasks; trained models can contain millions of parameters. These large models are compute- and memory-intensive, which makes it a challenge to deploy…

Machine Learning · Computer Science 2023-05-19 Chong Yu , Jeff Pool

Deep Gaussian processes (DGPs) are increasingly popular as predictive models in machine learning (ML) for their non-stationary flexibility and ability to cope with abrupt regime changes in training data. Here we explore DGPs as surrogates…

Methodology · Statistics 2021-08-27 Annie Sauer , Robert B. Gramacy , David Higdon

The essential task of urban planning is to generate the optimal land-use configuration of a target area. However, traditional urban planning is time-consuming and labor-intensive. Deep generative learning gives us hope that we can automate…

Artificial Intelligence · Computer Science 2022-12-05 Dongjie Wang , Lingfei Wu , Denghui Zhang , Jingbo Zhou , Leilei Sun , Yanjie Fu

Recent work introduced progressive network growing as a promising way to ease the training for large GANs, but the model design and architecture-growing strategy still remain under-explored and needs manual design for different image data.…

Computer Vision and Pattern Recognition · Computer Science 2021-06-17 Lanlan Liu , Yuting Zhang , Jia Deng , Stefano Soatto

We are interested in the design of generative networks. The training of these mathematical structures is mostly performed with the help of adversarial (min-max) optimization problems. We propose a simple methodology for constructing such…

Machine Learning · Computer Science 2021-07-16 Kalliopi Basioti , George V. Moustakides

In this paper, we propose to equip Generative Adversarial Networks with the ability to produce direct energy estimates for samples.Specifically, we propose a flexible adversarial training framework, and prove this framework not only ensures…

Machine Learning · Computer Science 2017-02-27 Zihang Dai , Amjad Almahairi , Philip Bachman , Eduard Hovy , Aaron Courville

Generative adversarial networks (GANs) are pairs of artificial neural networks that are trained one against each other. The outputs from a generator are mixed with the real-world inputs to the discriminator and both networks are trained…

Neural and Evolutionary Computing · Computer Science 2020-06-11 Andrei Kucharavy , El Mahdi El Mhamdi , Rachid Guerraoui