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Simulation-based inference (SBI) is transforming experimental sciences by enabling parameter estimation in complex non-linear models from simulated data. A persistent challenge, however, is model misspecification: simulators are only…

Machine Learning · Statistics 2025-10-20 Pierre-Louis Ruhlmann , Pedro L. C. Rodrigues , Michael Arbel , Florence Forbes

Simulation-based inference (SBI) is constantly in search of more expressive and efficient algorithms to accurately infer the parameters of complex simulation models. In line with this goal, we present consistency models for posterior…

Machine Learning · Computer Science 2024-11-05 Marvin Schmitt , Valentin Pratz , Ullrich Köthe , Paul-Christian Bürkner , Stefan T Radev

The cost of simulator evaluations is a key practical bottleneck for Simulation Based Inference (SBI). In hierarchical settings with shared global parameters and exchangeable site-level parameters and observations, this structure can be…

Machine Learning · Computer Science 2026-04-23 Giovanni Charles , Cosmo Santoni , Seth Flaxman , Elizaveta Semenova

The Laser Interferometer Space Antenna (LISA) data stream will inevitably contain gaps due to maintenance and environmental disturbances, introducing nonstationarities and spectral leakage that compromise standard frequency-domain…

Instrumentation and Methods for Astrophysics · Physics 2025-12-30 Ruiting Mao , Jeong Eun Lee , Matthew C. Edwards

Inferring atmospheric properties of exoplanets from observed spectra is key to understanding their formation, evolution, and habitability. Since traditional Bayesian approaches to atmospheric retrieval (e.g., nested sampling) are…

Instrumentation and Methods for Astrophysics · Physics 2024-12-25 Timothy D. Gebhard , Jonas Wildberger , Maximilian Dax , Annalena Kofler , Daniel Angerhausen , Sascha P. Quanz , Bernhard Schölkopf

Flow Matching (FM) models achieve remarkable results in generative tasks. Building upon diffusion models, FM's simulation-free training paradigm enables simplicity and efficiency but introduces a train-inference gap: model outputs cannot be…

Machine Learning · Computer Science 2026-01-30 Zhaoyi Li , Jingtao Ding , Yong Li , Shihua Li

Simulation-based inference (SBI) is an established approach for performing Bayesian inference on scientific simulators. SBI so far works best on low-dimensional parametric models. However, it is difficult to infer function-valued…

Machine Learning · Computer Science 2025-11-17 Guy Moss , Leah Sophie Muhle , Reinhard Drews , Jakob H. Macke , Cornelius Schröder

Building on the recent trend of new deep generative models known as Normalizing Flows (NF), simulation-based inference (SBI) algorithms can now efficiently accommodate arbitrary complex and high-dimensional data distributions. The…

Machine Learning · Statistics 2022-11-28 Julia Linhart , Alexandre Gramfort , Pedro L. C. Rodrigues

Identifying the parameters of a non-linear model that best explain observed data is a core task across scientific fields. When such models rely on complex simulators, evaluating the likelihood is typically intractable, making traditional…

Allocating extra computation at inference time has recently improved sample quality in large language models and diffusion-based image generation. In parallel, Flow Matching (FM) has gained traction in language, vision, and scientific…

Machine Learning · Computer Science 2025-10-21 Adam Stecklov , Noah El Rimawi-Fine , Mathieu Blanchette

Flow Matching (FM) is a simulation-free method for learning a continuous and invertible flow to interpolate between two distributions, and in particular to generate data from noise. Inspired by the variational nature of the diffusion…

Machine Learning · Statistics 2025-07-14 Chen Xu , Xiuyuan Cheng , Yao Xie

Computer simulations have long presented the exciting possibility of scientific insight into complex real-world processes. Despite the power of modern computing, however, it remains challenging to systematically perform inference under…

Machine Learning · Computer Science 2024-12-10 Sam Griesemer , Defu Cao , Zijun Cui , Carolina Osorio , Yan Liu

Flow-based generative modeling is a powerful tool for solving inverse problems in physical sciences that can be used for sampling and likelihood evaluation with much lower inference times than traditional methods. We propose to refine flows…

Machine Learning · Computer Science 2024-10-31 Benjamin Holzschuh , Nils Thuerey

Continuous diffusion and flow matching models could represent a powerful alternative to autoregressive approaches for language modelling (LM), as they unlock a host of advantages currently reserved for continuous modalities, including…

Machine Learning · Computer Science 2026-05-12 Oscar Davis , Anastasiia Filippova , Pierre Ablin , Victor Turrisi , Amitis Shidani , Marco Cuturi , Louis Béthune

Simulation-based inference (SBI) offers a flexible and general approach to performing Bayesian inference: In SBI, a neural network is trained on synthetic data simulated from a model and used to rapidly infer posterior distributions for…

Machine Learning · Computer Science 2025-10-28 Julius Vetter , Manuel Gloeckler , Daniel Gedon , Jakob H. Macke

We introduce Pawsterior, a variational flow-matching framework for improved and extended simulation-based inference (SBI). Many SBI problems involve posteriors constrained by structured domains, such as bounded physical parameters or hybrid…

Machine Learning · Computer Science 2026-03-10 Jorge Carrasco-Pollo , Floor Eijkelboom , Jan-Willem van de Meent

Simulation-Based Inference (SBI) is a promising Bayesian inference framework that alleviates the need for analytic likelihoods to estimate posterior distributions. Recent advances using neural density estimators in SBI algorithms have…

Instrumentation and Methods for Astrophysics · Physics 2022-07-13 Justine Zeghal , François Lanusse , Alexandre Boucaud , Benjamin Remy , Eric Aubourg

Generative models have excelled in audio tasks using approaches such as language models, diffusion, and flow matching. However, existing generative approaches for speech enhancement (SE) face notable challenges: language model-based methods…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-28 Ziqian Wang , Zikai Liu , Xinfa Zhu , Yike Zhu , Mingshuai Liu , Jun Chen , Longshuai Xiao , Chao Weng , Lei Xie

Flow matching has emerged as a simulation-free alternative to diffusion-based generative modeling, producing samples by solving an ODE whose time-dependent velocity field is learned along an interpolation between a simple source…

Machine Learning · Statistics 2026-04-10 Shivam Kumar , Yixin Wang , Lizhen Lin

We introduce a new paradigm for generative modeling built on Continuous Normalizing Flows (CNFs), allowing us to train CNFs at unprecedented scale. Specifically, we present the notion of Flow Matching (FM), a simulation-free approach for…

Machine Learning · Computer Science 2023-02-09 Yaron Lipman , Ricky T. Q. Chen , Heli Ben-Hamu , Maximilian Nickel , Matt Le
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