Related papers: A list-mode multi-energy window low-count SPECT re…
Single-photon emission computed tomography (SPECT) provides a mechanism to estimate regional isotope uptake in lesions and at-risk organs after administration of {\alpha}-particle-emitting radiopharmaceutical therapies ({\alpha}-RPTs).…
Reliable attenuation and scatter compensation (ASC) is a prerequisite for quantification and beneficial for visual interpretation tasks in SPECT. In this paper, we develop a reconstruction method that uses the entire SPECT emission data,…
Thorium-227-based alpha-particle radiopharmaceutical therapies ({\alpha}-RPTs) are being investigated in several clinical and pre-clinical studies. After administration, Thorium-227 decays to Radium-223, another alpha-particle-emitting…
In SPECT, list-mode (LM) format allows storing data at higher precision compared to binned data. There is significant interest in investigating whether this higher precision translates to improved performance on clinical tasks. Towards this…
SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…
This study compares two statistical approaches to image reconstruction in single-photon emission computed tomography (SPECT). We evaluated the widely used Ordered Subset Expectation Maximization (OSEM) algorithm and the newer Maximum a…
Low-dose computed tomography (LDCT) offers significant advantages in reducing the potential harm to human bodies. However, reducing the X-ray dose in CT scanning often leads to severe noise and artifacts in the reconstructed images, which…
We study the increase of image noise which can be observed in images reconstructed with the OSEM algorithm. We argue that the excessive noise is equivalent to shortening scanning time by a factor of 2 or more at high number of subsets…
Multi-Energy Computed Tomography (ME-CT) is a medical imaging modality aiming to reconstruct the spatial density of materials from the attenuation properties of probing x-rays. For each line in two- or three-dimensional space, ME-CT…
SPECT can enable the quantification of activity uptake in lesions and at-risk organs in {\alpha}-particle-emitting radiopharmaceutical therapies ({\alpha}-RPTs). But this quantification is challenged by the low photon counts, complicated…
In SPECT image reconstruction, limited-angle (LA) conditions lead to a loss of frequency components, which distort the reconstructed tomographic image along directions corresponding to the non-collected projection angle range. Although…
In this paper, we propose a unified energy minimization model for the segmentation of non-smooth image structures. The energy of piecewise linear patch reconstruction is considered as an objective measure of the quality of the segmentation…
Attenuation compensation (AC) is a pre-requisite for reliable quantification and beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT). Typical AC methods require the availability of an attenuation…
Low-count reconstruction remains a challenge for Positron Emission Tomography (PET) even with the recent progress in time-of-flight (TOF) resolution. In this context, the bias between the acquired histogram, consisting of low values or…
This paper discusses the reconstruction of partially sampled spectrum-images to accelerate the acquisition in scanning transmission electron microscopy (STEM). The problem of image reconstruction has been widely considered in the literature…
Standard dual-energy computed tomography (CT) uses two different X-ray energies to obtain energy-dependent tissue attenuation information to allow quantitative material decomposition. The combined use of dual-energy CT and positron emission…
To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most…
Multi-material decomposition (MMD) enables quantitative reconstruction of tissue compositions in the human body, supporting a wide range of clinical applications. However, traditional MMD typically requires spectral CT scanners and…
Electron microscopy has shown to be a very powerful tool to map the chemical nature of samples at various scales down to atomic resolution. However, many samples can not be analyzed with an acceptable signal-to-noise ratio because of the…
In this paper, we present a novel Bayesian approach for estimating spectral and range profiles from single-photon Lidar waveforms associated with single surfaces in the photon-limited regime. In contrast to classical multispectral Lidar…