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We present a fully convolutional neural network for segmenting ischemic stroke lesions in CT perfusion images for the ISLES 2018 challenge. Treatment of stroke is time sensitive and current standards for lesion identification require manual…

Computer Vision and Pattern Recognition · Computer Science 2018-11-06 S. Mazdak Abulnaga , Jonathan Rubin

We develop a deep learning model, ABioSPATH, to predict the one-year risk of ischemic stroke (IS) in atrial fibrillation (AF) patients. The model integrates drug-protein-disease pathways and real-world clinical data of AF patients to…

Quantitative Methods · Quantitative Biology 2024-08-27 Zhiheng Lyu , Jiannan Yang , Zhongzhi Xu , Weilan Wang , Weibin Cheng , Kwok-Leung Tsui , Gary Tse , Qingpeng Zhang

Successful identification of blood vessel blockage is a crucial step for Alzheimer's disease diagnosis. These blocks can be identified from the spatial and time-depth variable Two-Photon Excitation Microscopy (TPEF) images of the brain…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Partho Ghosh , Md. Abrar Istiak , Mir Sayeed Mohammad , Swapnil Saha , Uday Kamal

Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk…

Tissues and Organs · Quantitative Biology 2015-10-08 Andrew Parton , Victoria McGilligan , Maurice OKane , Francina R Baldrick , Steven Watterson

Delineating infarcted tissue in ischemic stroke lesions is crucial to determine the extend of damage and optimal treatment for this life-threatening condition. However, this problem remains challenging due to high variability of ischemic…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Jose Dolz , Ismail Ben Ayed , Christian Desrosiers

Pulmonary embolism, the obstruction of a pulmonary artery by a blood clot, is one of the leading causes of acute cardiovascular syndrome. In clinical practice, therapeutic decisions after diagnosis via computed tomography pulmonary…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Morgane des Ligneris , Nathan Painchaud , Allan Serva , Laurent Bertoletti , Pierre Croisille , Carole Frindel , Odyssée Merveille

With populations ageing, the number of people with dementia worldwide is expected to triple to 152 million by 2050. Seventy percent of cases are due to Alzheimer's disease (AD) pathology and there is a 10-20 year 'pre-clinical' period…

Artificial Intelligence · Computer Science 2021-04-30 Renjie Li , Xinyi Wang , Katherine Lawler , Saurabh Garg , Quan Bai , Jane Alty

Aortic stenosis (AS) is a degenerative valve condition that causes substantial morbidity and mortality. This condition is under-diagnosed and under-treated. In clinical practice, AS is diagnosed with expert review of transthoracic…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Zhe Huang , Benjamin S. Wessler , Michael C. Hughes

Head Non-contrast computed tomography (NCCT) scan remain the preferred primary imaging modality due to their widespread availability and speed. However, the current standard for manual annotations of abnormal brain tissue on head NCCT scans…

Image and Video Processing · Electrical Eng. & Systems 2023-07-11 Arunkumar Govindarajan , Arjun Agarwal , Subhankar Chattoraj , Dennis Robert , Satish Golla , Ujjwal Upadhyay , Swetha Tanamala , Aarthi Govindarajan

Intracerebral hemorrhage (ICH) is a severe and sudden medical condition caused by the rupture of blood vessels in the brain, leading to permanent damage to brain tissue and often resulting in functional disabilities or death in patients.…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Jialiang Fan , Xinhui Fan , Chengyan Song , Xiaofan Wang , Bingdong Feng , Lucan Li , Guoyu Lu

Accurate infarct segmentation in non-contrast CT (NCCT) images is a crucial step toward computer-aided acute ischemic stroke (AIS) assessment. In clinical practice, bilateral symmetric comparison of brain hemispheres is usually used to…

Image and Video Processing · Electrical Eng. & Systems 2022-07-01 Haomiao Ni , Yuan Xue , Kelvin Wong , John Volpi , Stephen T. C. Wong , James Z. Wang , Xiaolei Huang

Since stroke is the main cause of various cerebrovascular diseases, deep learning-based stroke lesion segmentation on magnetic resonance (MR) images has attracted considerable attention. However, the existing methods often neglect the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-03 Weiyi Yu , Yiming Lei , Hongming Shan

Intracranial hemorrhage occurs when blood vessels rupture or leak within the brain tissue or elsewhere inside the skull. It can be caused by physical trauma or by various medical conditions and in many cases leads to death. The treatment…

Computer Vision and Pattern Recognition · Computer Science 2021-05-14 Kimmo Kärkkäinen , Shayan Fazeli , Majid Sarrafzadeh

Accurate delineation of acute ischemic stroke lesions in MRI is a key component of stroke diagnosis and management. In recent years, deep learning models have been successfully applied to the automatic segmentation of such lesions. While…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Vincent Roca , Martin Bretzner , Hilde Henon , Laurent Puy , Grégory Kuchcinski , Renaud Lopes

Atrial fibrillation (AF) is the most common cardiac arrhythmia, which is clinically identified with irregular and rapid heartbeat rhythm. AF puts a patient at risk of forming blood clots, which can eventually lead to heart failure, stroke,…

Signal Processing · Electrical Eng. & Systems 2023-06-28 Jianxin Xie , Stavros Stavrakis , Bing Yao

We present StrokeNeXt, a model for stroke classification in 2D Computed Tomography (CT) images. StrokeNeXt employs a dual-branch design with two ConvNeXt encoders, whose features are fused through a lightweight convolutional decoder based…

Image and Video Processing · Electrical Eng. & Systems 2026-02-18 Leo Thomas Ramos , Angel D. Sappa

Rapid triage of suspected stroke needs accurate, bedside-deployable tools; EEG is promising but underused at first contact. We present an adaptive multitask EEG classifier that converts 32-channel signals to power spectral density features…

Machine Learning · Computer Science 2025-11-13 Shakeel Abdulkareem , Bora Yimenicioglu , Khartik Uppalapati , Aneesh Gudipati , Adan Eftekhari , Saleh Yassin

Intracranial hemorrhage (ICH) is a pathological condition characterized by bleeding inside the skull or brain, which can be attributed to various factors. Identifying, localizing and quantifying ICH has important clinical implications, in a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Biao Wu , Yutong Xie , Zeyu Zhang , Jinchao Ge , Kaspar Yaxley , Suzan Bahadir , Qi Wu , Yifan Liu , Minh-Son To

Brain stroke remains one of the principal causes of death and disability worldwide, yet most tabular-data prediction models still hover below the 95% accuracy threshold, limiting real-world utility. Addressing this gap, the present work…

Quantitative Methods · Quantitative Biology 2026-05-22 Yousuf Islam , Md. Jalal Uddin Chowdhury , Sumon Chandra Das

Stroke is a leading cause of neurological injury characterized by impairments in multiple neurological domains including cognition, language, sensory and motor functions. Clinical recovery in these domains is tracked using a wide range of…

Quantitative Methods · Quantitative Biology 2021-10-01 Sanjukta Krishnagopal , Keith Lohse , Robynne Braun