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The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

Quantitative Methods · Quantitative Biology 2023-05-01 Louise Budzynski , Andrea Pagnani

We developed a novel approach to identification and model testing in linear structural equation models (SEMs) based on auxiliary variables (AVs), which generalizes a widely-used family of methods known as instrumental variables. The…

Methodology · Statistics 2019-10-09 Bryant Chen , Daniel Kumor , Elias Bareinboim

Recommender systems have been studied extensively due to their practical use in many real-world scenarios. Despite this, generating effective recommendations with sparse user ratings remains a challenge. Side information associated with…

Information Retrieval · Computer Science 2018-07-17 Yifan Chen , Maarten de Rijke

The goal of this work is to efficiently identify visually similar patterns in images, e.g. identifying an artwork detail copied between an engraving and an oil painting, or recognizing parts of a night-time photograph visible in its daytime…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Xi Shen , Alexei A. Efros , Armand Joulin , Mathieu Aubry

In this work, we demonstrate that affine mappings between residual streams of language models is a cheap way to effectively transfer represented features between models. We apply this technique to transfer the weights of Sparse Autoencoders…

Computation and Language · Computer Science 2025-11-04 Alan Chen , Jack Merullo , Alessandro Stolfo , Ellie Pavlick

Karyotyping is of importance for detecting chromosomal aberrations in human disease. However, chromosomes easily appear curved in microscopic images, which prevents cytogeneticists from analyzing chromosome types. To address this issue, we…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Jingxiong Li , Sunyi Zheng , Zhongyi Shui , Shichuan Zhang , Linyi Yang , Yuxuan Sun , Yunlong Zhang , Honglin Li , Yuanxin Ye , Peter M. A. van Ooijen , Kang Li , Lin Yang

This extended abstract presents a visualization system, which is designed for domain scientists to visually understand their deep learning model of extracting multiple attributes in x-ray scattering images. The system focuses on studying…

Machine Learning · Computer Science 2019-10-11 Xinyi Huang , Suphanut Jamonnak , Ye Zhao , Boyu Wang , Minh Hoai , Kevin Yager , Wei Xu

Foundation model approaches such as masked auto-encoders (MAE) or its variations are now being successfully applied to satellite imagery. Most of the ongoing technical validation of foundation models have been applied to optical images like…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Ali Caglayan , Nevrez Imamoglu , Toru Kouyama

Masked Autoencoders (MAEs) have emerged as a powerful pretraining technique for vision foundation models. Despite their effectiveness, they require extensive hyperparameter tuning (masking ratio, patch size, encoder/decoder layers) when…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Anthony Bisulco , Rahul Ramesh , Randall Balestriero , Pratik Chaudhari

The 4D scanning transmission electron microscopy (STEM) method has enabled mapping of the structure and functionality of solids on the atomic scale, yielding information-rich data sets containing information on the interatomic electric and…

Computational Physics · Physics 2020-09-24 Mark P. Oxley , Maxim Ziatdinov , Ondrej Dyck , Andrew R. Lupini , Rama Vasudevan , Sergei V. Kalinin

The morphology of block copolymers (BCPs) critically influences material properties and applications. This work introduces a machine learning (ML)-enabled, high-throughput framework for analyzing grazing incidence small-angle X-ray…

Principal Component Analysis (PCA) minimizes the reconstruction error given a class of linear models of fixed component dimensionality. Probabilistic PCA adds a probabilistic structure by learning the probability distribution of the PCA…

Machine Learning · Computer Science 2022-09-20 Vanessa Böhm , Uroš Seljak

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

Recent 3D content generation pipelines commonly employ Variational Autoencoders (VAEs) to encode shapes into compact latent representations for diffusion-based generation. However, the widely adopted uniform point sampling strategy in Shape…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Rui Chen , Jianfeng Zhang , Yixun Liang , Guan Luo , Weiyu Li , Jiarui Liu , Xiu Li , Xiaoxiao Long , Jiashi Feng , Ping Tan

Understanding structure-property relationships in complex materials requires integrating complementary measurements across multiple length scales. Here we propose an interpretable "multimodal" machine learning framework that unifies…

Materials Science · Physics 2026-02-03 Shun Muroga , Hideaki Nakajima , Taiyo Shimizu , Kazufumi Kobashi , Kenji Hata

Masked AutoEncoders (MAE) have emerged as a robust self-supervised framework, offering remarkable performance across a wide range of downstream tasks. To increase the difficulty of the pretext task and learn richer visual representations,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Carlos Hinojosa , Shuming Liu , Bernard Ghanem

While sparse autoencoders (SAEs) successfully extract interpretable features from language models, applying them to audio generation faces unique challenges: audio's dense nature requires compression that obscures semantic meaning, and…

Machine Learning · Computer Science 2025-10-31 Nathan Paek , Yongyi Zang , Qihui Yang , Randal Leistikow

Establishing the structure-property relationship in amorphous materials has been a long-term grand challenge due to the lack of a unified description of the degree of disorder. In this work, we develop SPRamNet, a neural network based…

Materials Science · Physics 2024-10-07 Mouyang Cheng , Chenyan Wang , Chenxin Qin , Yuxiang Zhang , Qingyuan Zhang , Han Li , Ji Chen

The routine and unique determination of minor phases in microstructures is critical to materials science. In metallurgy alone, applications include alloy and process development and the understanding of degradation in service. We develop a…

Materials Science · Physics 2020-01-22 T. P. McAuliffe , A. Foden , C. Bilsland , D. Daskalaki-Mountanou , D. Dye , T. B. Britton

Feature selection is a crucial task in settings where data is high-dimensional or acquiring the full set of features is costly. Recent developments in neural network-based embedded feature selection show promising results across a wide…

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