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The widespread adoption of electronic health records (EHRs) and subsequent increased availability of longitudinal healthcare data has led to significant advances in our understanding of health and disease with direct and immediate impact on…

Machine Learning · Computer Science 2022-01-21 Simon Bing , Andrea Dittadi , Stefan Bauer , Patrick Schwab

Synthetic Electronic Health Records (EHR) have emerged as a pivotal tool in advancing healthcare applications and machine learning models, particularly for researchers without direct access to healthcare data. Although existing methods,…

Synthetic health data have the potential to mitigate privacy concerns when sharing data to support biomedical research and the development of innovative healthcare applications. Modern approaches for data generation based on machine…

Machine Learning · Computer Science 2023-01-11 Chao Yan , Yao Yan , Zhiyu Wan , Ziqi Zhang , Larsson Omberg , Justin Guinney , Sean D. Mooney , Bradley A. Malin

Generative models have been found effective for data synthesis due to their ability to capture complex underlying data distributions. The quality of generated data from these models is commonly evaluated by visual inspection for image…

Machine Learning · Computer Science 2022-10-18 Emily Muller , Xu Zheng , Jer Hayes

Sensitive medical data is often subject to strict usage constraints. In this paper, we trained a generative adversarial network (GAN) on real-world electronic health records (EHR). It was then used to create a data-set of "fake" patients…

Machine Learning · Computer Science 2021-09-07 John Weldon , Tomas Ward , Eoin Brophy

Electronic health records (EHRs) have become the foundation of machine learning applications in healthcare, while the utility of real patient records is often limited by privacy and security concerns. Synthetic EHR generation provides an…

Artificial Intelligence · Computer Science 2023-12-25 Hongda Sun , Hongzhan Lin , Rui Yan

Class imbalance can often degrade predictive performance of supervised learning algorithms. Balanced classes can be obtained by oversampling exact copies, with noise, or interpolation between nearest neighbours (as in traditional SMOTE…

Machine Learning · Computer Science 2022-01-17 Emily Muller , Xu Zheng , Jer Hayes

The recent availability of electronic health records (EHRs) have provided enormous opportunities to develop artificial intelligence (AI) algorithms. However, patient privacy has become a major concern that limits data sharing across…

Machine Learning · Computer Science 2023-02-01 Jin Li , Benjamin J. Cairns , Jingsong Li , Tingting Zhu

Despite significant recent progress in the area of Brain-Computer Interface (BCI), there are numerous shortcomings associated with collecting Electroencephalography (EEG) signals in real-world environments. These include, but are not…

Quantitative Methods · Quantitative Biology 2019-10-14 Nik Khadijah Nik Aznan , Amir Atapour-Abarghouei , Stephen Bonner , Jason Connolly , Noura Al Moubayed , Toby Breckon

Accessing longitudinal multimodal Electronic Healthcare Records (EHRs) is challenging due to privacy concerns, which hinders the use of ML for healthcare applications. Synthetic EHRs generation bypasses the need to share sensitive real…

Computation and Language · Computer Science 2022-11-04 Zifeng Wang , Jimeng Sun

Generating synthetic Electronic Health Records (EHRs) offers significant potential for data augmentation, privacy-preserving data sharing, and improving machine learning model training. We propose a novel tokenization strategy tailored for…

Machine Learning · Computer Science 2024-11-21 Hojjat Karami , David Atienza , Anisoara Ionescu

We conduct a scoping review of existing approaches for synthetic EHR data generation, and benchmark major methods with proposed open-source software to offer recommendations for practitioners. We search three academic databases for our…

Machine Learning · Computer Science 2025-06-05 Xingran Chen , Zhenke Wu , Xu Shi , Hyunghoon Cho , Bhramar Mukherjee

Synthetic data generation offers a promising solution to enhance the usefulness of Electronic Healthcare Records (EHR) by generating realistic de-identified data. However, the existing literature primarily focuses on the quality of…

Machine Learning · Computer Science 2024-04-29 Resmi Ramachandranpillai , Md Fahim Sikder , David Bergström , Fredrik Heintz

Due to patient privacy protection concerns, machine learning research in healthcare has been undeniably slower and limited than in other application domains. High-quality, realistic, synthetic electronic health records (EHRs) can be…

Machine Learning · Computer Science 2023-02-10 Huan He , Shifan Zhao , Yuanzhe Xi , Joyce C Ho

Access to electronic health records (EHRs) for digital health research is often limited by privacy regulations and institutional barriers. Synthetic EHRs have been proposed as a way to enable safe and sovereign data sharing; however,…

Machine Learning · Computer Science 2026-03-10 Guanglin Zhou , Armin Catic , Motahare Shabestari , Matthew Young , Chaiquan Li , Katrina Poppe , Sebastiano Barbieri

Electronic Health Records (EHRs) are commonly used by the machine learning community for research on problems specifically related to health care and medicine. EHRs have the advantages that they can be easily distributed and contain many…

Machine Learning · Computer Science 2020-06-08 Kieran Chin-Cheong , Thomas Sutter , Julia E. Vogt

Sharing electronic health records (EHRs) on a large scale may lead to privacy intrusions. Recent research has shown that risks may be mitigated by simulating EHRs through generative adversarial network (GAN) frameworks. Yet the methods…

Machine Learning · Computer Science 2020-03-25 Chao Yan , Ziqi Zhang , Steve Nyemba , Bradley A. Malin

Access to electronic health record (EHR) data has motivated computational advances in medical research. However, various concerns, particularly over privacy, can limit access to and collaborative use of EHR data. Sharing synthetic EHR data…

Machine Learning · Computer Science 2018-01-15 Edward Choi , Siddharth Biswal , Bradley Malin , Jon Duke , Walter F. Stewart , Jimeng Sun

Synthesizing electronic health records (EHR) data has become a preferred strategy to address data scarcity, improve data quality, and model fairness in healthcare. However, existing approaches for EHR data generation predominantly rely on…

Machine Learning · Computer Science 2024-06-21 Yuan Zhong , Xiaochen Wang , Jiaqi Wang , Xiaokun Zhang , Yaqing Wang , Mengdi Huai , Cao Xiao , Fenglong Ma

Synthetic Electronic Health Records (EHRs) offer a valuable opportunity to create privacy preserving and harmonized structured data, supporting numerous applications in healthcare. Key benefits of synthetic data include precise control over…

Computation and Language · Computer Science 2025-04-28 Yihan Lin , Zhirong Bella Yu , Simon Lee
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