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Recent studies on modelling the progression of Alzheimer's disease use a single modality for their predictions while ignoring the time dimension. However, the nature of patient data is heterogeneous and time dependent which requires models…

Computers and Society · Computer Science 2021-10-19 Sofia Lahrichi , Maryem Rhanoui , Mounia Mikram , Bouchra El Asri

Recent years have seen a surge in research focused on leveraging graph learning techniques to detect neurodegenerative diseases. However, existing graph-based approaches typically lack the ability to localize and extract the specific brain…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Nguyen Linh Dan Le , Jing Ren , Ciyuan Peng , Chengyao Xie , Bowen Li , Feng Xia

Brain imaging has allowed neuroscientists to analyze brain morphology in genetic and neurodevelopmental disorders, such as Down syndrome, pinpointing regions of interest to unravel the neuroanatomical underpinnings of cognitive impairment…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Jordi Malé , Juan Fortea , Mateus Rozalem Aranha , Yann Heuzé , Neus Martínez-Abadías , Xavier Sevillano

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…

Signal Processing · Electrical Eng. & Systems 2024-04-02 Arezoo Borji , Taha-Hossein Hejazi , Abbas Seifi

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease which destroys brain cells and causes loss to patient's memory. An early detection can prevent the patient from further damage of the brain cells and hence…

Image and Video Processing · Electrical Eng. & Systems 2021-01-11 Ali Nawaz , Syed Muhammad Anwar , Rehan Liaqat , Javid Iqbal , Ulas Bagci , Muhammad Majid

With rapid advances in neuroimaging techniques, the research on brain disorder identification has become an emerging area in the data mining community. Brain disorder data poses many unique challenges for data mining research. For example,…

Machine Learning · Computer Science 2015-08-06 Bokai Cao , Xiangnan Kong , Philip S. Yu

Multimodal medical imaging plays a pivotal role in clinical diagnosis and research, as it combines information from various imaging modalities to provide a more comprehensive understanding of the underlying pathology. Recently, deep…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Yihao Li , Mostafa El Habib Daho , Pierre-Henri Conze , Rachid Zeghlache , Hugo Le Boité , Ramin Tadayoni , Béatrice Cochener , Mathieu Lamard , Gwenolé Quellec

Arguably, unsupervised learning plays a crucial role in the majority of algorithms for processing brain imaging. A recently introduced unsupervised approach Deep InfoMax (DIM) is a promising tool for exploring brain structure in a flexible…

Machine Learning · Computer Science 2019-05-02 Alex Fedorov , R Devon Hjelm , Anees Abrol , Zening Fu , Yuhui Du , Sergey Plis , Vince D. Calhoun

This study is based on the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset and aims to explore early detection and disease progression in Alzheimer's disease (AD). We employ innovative data preprocessing strategies, including the…

Machine Learning · Computer Science 2024-02-14 Mingyang Li , Hongyu Liu , Yixuan Li , Zejun Wang , Yuan Yuan , Honglin Dai

Alzheimer's disease (AD) is a prevalent and debilitating neurodegenerative disorder impacting a large aging population. Detecting AD in all its presymptomatic and symptomatic stages is crucial for early intervention and treatment. An active…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Yasmine Mustafa , Tie Luo

We propose a unified deep meta-learning framework for accelerated magnetic resonance imaging (MRI) that jointly addresses multi-coil reconstruction and cross-modality synthesis. Motivated by the limitations of conventional methods in…

Optimization and Control · Mathematics 2026-03-10 Merham Fouladvand , Peuroly Batra

Multimodal neuroimaging provides complementary insights for Alzheimer's disease diagnosis, yet clinical datasets frequently suffer from missing modalities. We propose ACADiff, a framework that synthesizes missing brain imaging modalities…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Rong Zhou , Houliang Zhou , Yao Su , Brian Y. Chen , Yu Zhang , Lifang He , Alzheimer's Disease Neuroimaging Initiative

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

In real world clinical environments, training and applying deep learning models on multi-modal medical imaging data often struggles with partially incomplete data. Standard approaches either discard missing samples, require imputation or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Christoph Fürböck , Paul Weiser , Branko Mitic , Philipp Seeböck , Thomas Helbich , Georg Langs

Multi-domain data are widely leveraged in vision applications taking advantage of complementary information from different modalities, e.g., brain tumor segmentation from multi-parametric magnetic resonance imaging (MRI). However, due to…

Alzheimer disease is a severe brain disorder that causes harm in various brain areas and leads to memory damage. The limited availability of labeled medical data poses a significant challenge for accurate Alzheimer disease detection. There…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Safa Ben Atitallah , Maha Driss , Wadii Boulila , Anis Koubaa

Biomarker discovery in neurodegenerative diseases requires robust, interpretable frameworks capable of integrating high-dimensional multi-omics data under low-sample conditions. We propose a novel ensemble approach combining Graph Attention…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Byeonghee Lee , Joonsung Kang

Multimodal medical image fusion plays an instrumental role in several areas of medical image processing, particularly in disease recognition and tumor detection. Traditional fusion methods tend to process each modality independently before…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Lin Liu , Xinxin Fan , Chulong Zhang , Jingjing Dai , Yaoqin Xie , Xiaokun Liang
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