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There is strong interest in estimating how the magnitude of treatment effects of an intervention vary across sub-groups of the population of interest. In our paper, we propose a two-study approach to first propose and then test…

Methodology · Statistics 2020-06-23 Rahul Ladhania , Amelia Haviland , Neeraj Sood , Edward Kennedy , Ateev Mehrotra

Estimating heterogeneous treatment effects (HTEs) is crucial for personalized decision-making. However, this task is challenging in survival analysis, which includes time-to-event data with censored outcomes (e.g., due to study dropout). In…

Machine Learning · Computer Science 2025-05-20 Dennis Frauen , Maresa Schröder , Konstantin Hess , Stefan Feuerriegel

This study proposes a novel framework based on the RuleFit method to estimate Heterogeneous Treatment Effect (HTE) in a randomized clinical trial. To achieve this, we adopted S-learner of the metaalgorithm for our proposed framework. The…

Methodology · Statistics 2023-07-28 Mayu Hiraishi , Ke Wan , Kensuke Tanioka , Hiroshi Yadohisa , Toshio Shimokawa

In a feedforward network, Transfer Entropy (TE) can be used to measure the influence that one layer has on another by quantifying the information transfer between them during training. According to the Information Bottleneck principle, a…

Machine Learning · Computer Science 2024-04-03 Adrian Moldovan , Angel Cataron , Razvan Andonie

Individual treatment effect estimation has gained significant attention in recent data science literature. This work introduces the Double Neural Network (Double-NN) method to address this problem within the framework of extended fiducial…

Machine Learning · Statistics 2025-05-06 Sehwan Kim , Faming Liang

Surgical decision-making is complex and requires understanding causal relationships between patient characteristics, interventions, and outcomes. In high-stakes settings like spinal fusion or scoliosis correction, accurate estimation of…

Irregularly sampled time series (ISTS) data has irregular temporal intervals between observations and different sampling rates between sequences. ISTS commonly appears in healthcare, economics, and geoscience. Especially in the medical…

Machine Learning · Computer Science 2020-10-27 Chenxi Sun , Shenda Hong , Moxian Song , Hongyan Li

Although there is now a large literature on policy evaluation and learning, much of the prior work assumes that the treatment assignment of one unit does not affect the outcome of another unit. Unfortunately, ignoring interference can lead…

Methodology · Statistics 2025-04-02 Yi Zhang , Kosuke Imai

Observational data have been actively used to estimate treatment effect, driven by the growing availability of electronic health records (EHRs). However, EHRs typically consist of longitudinal records, often introducing time-dependent…

Machine Learning · Computer Science 2024-06-14 Junghwan Lee , Simin Ma , Nicoleta Serban , Shihao Yang

We address the problem of estimating heterogeneous treatment effects in panel data, adopting the popular Difference-in-Differences (DiD) framework under the conditional parallel trends assumption. We propose a novel doubly robust…

Machine Learning · Statistics 2025-04-29 Hui Lan , Haoge Chang , Eleanor Dillon , Vasilis Syrgkanis

Under distribution shift (DS) where the training data distribution differs from the test one, a powerful technique is importance weighting (IW) which handles DS in two separate steps: weight estimation (WE) estimates the test-over-training…

Machine Learning · Computer Science 2020-11-06 Tongtong Fang , Nan Lu , Gang Niu , Masashi Sugiyama

We consider estimation of the target population average treatment effect (TATE) when outcome information is unavailable. Instead, we observe the outcome in multiple source populations and wish to combine the treatment effects therein to…

Methodology · Statistics 2025-05-16 Zehao Su , Helene Charlotte Rytgaard , Henrik Ravn , Frank Eriksson

Building accurate models for rare skin diseases remains challenging due to the lack of sufficient labeled data and the inherently long-tailed distribution of available samples. These issues are further complicated by inconsistencies in how…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Zeynep Özdemir , Hacer Yalim Keles , Ömer Özgür Tanrıöver

Deep learning models have proven to be effective on medical datasets for accurate diagnostic predictions from images. However, medical datasets often contain noisy, mislabeled, or poorly generalizable images, particularly for edge cases and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Ruhaan Singh , Sreelekha Guggilam

This paper introduces an efficient sub-model ensemble framework aimed at enhancing the interpretability of medical deep learning models, thus increasing their clinical applicability. By generating uncertainty maps, this framework enables…

Machine Learning · Computer Science 2024-11-11 Weijie Chen , Alan McMillan

Robust estimation of heterogeneous treatment effects is a fundamental challenge for optimal decision-making in domains ranging from personalized medicine to educational policy. In recent years, predictive machine learning has emerged as a…

Machine Learning · Statistics 2025-06-23 Maximilian Schuessler , Erik Sverdrup , Robert Tibshirani

Machine learning (ML) holds great potential for accurately forecasting treatment outcomes over time, which could ultimately enable the adoption of more individualized treatment strategies in many practical applications. However, a…

Machine Learning · Statistics 2023-06-08 Toon Vanderschueren , Alicia Curth , Wouter Verbeke , Mihaela van der Schaar

Estimating the conditional average treatment effect (CATE) from observational data is relevant for many applications such as personalized medicine. Here, we focus on the widespread setting where the observational data come from multiple…

Machine Learning · Computer Science 2024-06-05 Jonas Schweisthal , Dennis Frauen , Mihaela van der Schaar , Stefan Feuerriegel

We present a new approach for transferring knowledge from groups to individuals that comprise them. We evaluate our method in text, by inferring the ratings of individual sentences using full-review ratings. This approach, which combines…

Machine Learning · Computer Science 2014-12-11 Dimitrios Kotzias , Misha Denil , Phil Blunsom , Nando de Freitas

Ensemble Adversarial Training (EAT) attempts to enhance the robustness of models against adversarial attacks by leveraging multiple models. However, current EAT strategies tend to train the sub-models independently, ignoring the cooperative…

Machine Learning · Computer Science 2025-09-03 Li Dengjin , Guo Yanming , Xie Yuxiang , Li Zheng , Chen Jiangming , Li Xiaolong , Lao Mingrui
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